Maria Céu Sousa (Sousa MC)
Integrated member
Group at CNC

Personal Information
Name: Maria do Céu Rodrigues de Sousa
Nationality: Portuguese
Institutional address: Faculdade de Farmácia da Universidade de Coimbra,
Pólo das Ciências da Saúde, Azinhaga de Santa Comba,
3000-548 Coimbra, Portugal.

Academic Degree
Ph. D. in Pharmacy, Microbiology and Parasitology specialty, Faculty of Pharmacy, University of Coimbra, Portugal, 19th December, 2002.

Proof of Pedagogic Aptitude and Scientific Capacity (the same academic level in Portugal as a Master degree), 15th January, 1993.

Graduated in Pharmaceutical Sciences (6 years degree), Faculty of Pharmacy,
University of Coimbra, Portugal, July, 1987.

Work experience
Teaching Assistant (Biological Sciences group), Faculty of Pharmacy of University of Coimbra (FFUC) (1988-1993). Teaching laboratory classes of General Microbiology, General Parasitology.

Assistant (Biological Sciences group), Faculty of Pharmacy of University of Coimbra (FFUC) (1993-2002). Teaching laboratory classes of General Microbiology and General Parasitology.

Assistant Professor (Biological Sciences group), Faculty of Pharmacy of University of Coimbra (FFUC) (2002- ).Teaching laboratory classes of Microbiology and Immunology, Hygiene and Public Health; Teaching of theoretical and laboratory classes at undergraduate and postgraduate courses: Parasitology and Parasitological Analysis; General Microbiology; Clinical Microbiology, Microbiology and Public Health; Food Microbiology; Clinical Mycology; Teacher in charge and coordination of Parasitology and Parasitological Analysis; Clinical Microbiology; Clinical Parasitology.

Coordinator of Doctoral thesis: five thesis (one finished and four on course)

Coordinator of Master thesis: ten thesis (8 finished and two in course)

Coordinator of Post-Doc: three post-graduate internships with a CNPq grants, Brasil.



Area of Research: 

Clinical parasitology and epidemiology:
- Giardia lamblia infections (giardiasis): molecular epidemiology studies and molecular mechanisms involved in pathogenesis.

Antiparasitic drugs
-Treatment of giardiasis, leishmaniasis and trypanosomiasis: drug discovery.

Research Summary:
Selected Publications: 

- Sousa M.C, Varandas R., Santos R.C., Santos-Rosa M, Alves V. Salvador J.A.R. “Antileismanial activity of semisynthetic lupane triterpenoids betulin and betulinic acid derivatives: synergistic effects with miltefosine” Plos One 2014, 18; 9(3):e89939. doi: 10.1371/journal.pone.0089939 (Impact factor: )

- Machado M, Dinis AM; Santos-Rosa M, Alves V Salgueiro L Cavaleiro C., Sousa MC. “Activity of Thymus capitellatus volatile extract, 1,8-cineole and borneol against Leishmania species” Veterinary Parasitology 2014, 200 (1-2):39-49. doi: 10.1016/j.vetpar.2013.11.016. (Impact factor:

- Machado M, Dinis AM, Salgueiro L, Cavaleiro C, Custódio JBA, Sousa MC. “Anti-Giardia activity of phenolic-rich essential oils: effects of Thymbra capitata, Origanum virens, Thymus zygis subsp. sylvestris and Lippia graveolens on trophozoites growth, viability, adherence and ultrastructure.” Parasitology Research 2010, 106 (5): 1205-15. (Impact factor:)

- Sousa, M. C., C. A. Gonçalves, V. A. Bairos, and J. Poiares-da-Silva. Adherence of Giardia lamblia trophozoites to Int-407 Human Intestinal Cell Line. Clinical and Diagnostic Laboratory Immunology 2001, 8: 258-265.(Impact factor:

- Sousa, M. C. and J. Poiares-da-Silva. A new method for assessing metronidazole susceptibility of Giardia lamblia trophozoites. Antimicrobial Agents and Chemotherapy 1999, 43: 2939-2942. (Impact factor:)

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