Maria Teresa Cruz
239 480 200
Principal Investigator at CNC, Assistant Professor, FFUC
Group at CNC

PhD in Pharmacology, Univ. Coimbra, 2004
Researcher (FCT Fellowship), FFUC, CNC, 1994-1996
MsC in Tecnologias do Medicamento (Univ. Coimbra, 1996)
PharmD in Pharmaceutical Sciences, Faculty of Pharmacy, Univ. Lisboa, 1992



Area of Research: 

in vitro toxicology, inflammation, immunopharmacology

Research Summary:
Selected Publications: 

Development of a dendritic cell-derived in vitro test to detect skin sensitizers (patent PCT/PT2012/000018)

Autophagy. 2016 Jan 2;12(1):1-222. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Silva A, Nunes C, Martins J, Dinis TC, Lopes C, Neves B, Cruz MT. Respiratory sensitizer hexamethylene diisocyanate inhibits SOD 1 and induces ERK-dependent detoxifying and maturation pathways on dendritic-like cells". Free Radical Biology and Medicine, 2014, 72:238-246.

Francisco V, Figueirinha A, Costa G, Liberal J, Lopes MC, García-Rodríguez C, Geraldes C. F.G.C., Cruz MT, Batista MT. Chemical characterization and anti-inflammatory activity of luteolin glycosides isolated from lemongrass. Journal of Functional Foods, 10, 2014, 436–443.

Resende M, Moreira D, Augusto J, Cunha J, Neves B, Cruz MT, Estaquier J, Cordeiro-da-Silva A, Silvestre R. Leishmania-Infected MHC Class IIhigh Dendritic Cells Polarize CD4+ T Cells toward a Nonprotective T-bet+ IFN-g+ IL-10+ Phenotype. J Immunol. 2013, 191, 262-73.

Financiado por Fundos FEDER através do Programa Operacional Factores de Competitividade – COMPETE 2020 e por Fundos Nacionais através da FCT – Fundação para a Ciência e a Tecnologia no âmbito do projecto Estratégico com referência atribuida pelo COMPETE: POCI-01-0145-FEDER-007440

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