Mariana Botelho
(+351) 239 820 190
PhD Student
Group at CNC

Mariana Botelho has a master degree in Pharmaceutical Sciences in 2010 by the Faculty of Pharmacy of the University of Coimbra, with the final mark of 17 in 20. Later in 2011, received a FCT grant to develop her PhD project under the scientific supervision of Professor Cláudia Cavadas, at the CNC -Center for Neuroscience and Cell Biology, University of Coimbra. Between 2011 and 2012, Mariana Botelho was at Yale University, USA, to develop part of PhD project under the supervision of Professor Tamas Horvath. In  2015, Mariana Botelho will present her doctoral thesis to the Faculty of Pharmacy, University of Coimbra, with specialization in Pharmacology and Pharmacotherapy.



Area of Research: 

Neuropeptide Y, Aging, Hypothalamus and Synaptic Plasticity

Research Summary:
Selected Publications: 

Botelho M, Cavadas C. Neuropeptide Y: an anti-aging player? (2015, Trends in Neurosciences, in press) - IF: 13.555

Aveleira C A*, Botelho M*, Cavadas C. NPY/neuropeptide Y enhances autophagy in the hypothalamus: a mechanism to delay aging? (2015, Autophagy, in press) * equally contribution - IF: 11.42

Aveleira C A*, Botelho M*, Carmo-Silva S, Pascoal J, Ferreira-Marques M, Nóbrega C, Cortes L, Valero J, Sousa-Ferreira L, Álvaro A R, Santana M, Kügler S, Pereira de Almeida L, Cavadas C. Neuropeptide Y stimulates autophagy in hypothalamic neurons. (2015, PNAS, 112(13):E1642-51) * equally contribution - IF: 9.674

Sousa‐Ferreira L, Aveleira CA, Botelho M, Álvaro AR, de Almeida LP, Cavadas C. Fluoxetine Induces Proliferation and Inhibits Differentiation of Hypothalamic Neuroprogenitor Cells In Vitro. (2014, PlosOne 2014 Mar 5;9(3):e88917).- IF: 3.534

Other information: 
Financiado por Fundos FEDER através do Programa Operacional Factores de Competitividade – COMPETE 2020 e por Fundos Nacionais através da FCT – Fundação para a Ciência e a Tecnologia no âmbito do projecto Estratégico com referência atribuida pelo COMPETE: POCI-01-0145-FEDER-007440

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