Magda M Santana (Santana MM; Santana M)
Post-doctoral researcher
Group at CNC

Magda M Santana has been in charge of translational research in the field of Neurosciences and aging-related diseases.  As undergraduate student, she was in the ranking of the 3% Best Students of Pharmaceutical Sciences. Magda Santana finished her Integrated Master in Pharmaceutical Sciences, in 2008, at the Faculty of Pharmacy, University of Coimbra, Portugal.
In the same year, Magda Santana received a PhD fellowship from Fundação para a Ciência e Tecnologia (FCT) to develop her PhD, under the supervision of Prof. Cláudia Cavadas, from the Neuroendocrinology and Aging Group, Center for Neuroscience and Cell Biology, University of Coimbra, Portugal and under the co-supervision of Monika Ehrhart-Bornstein, from the Molecular Endocrinology Group, Medical Clinic III, Carl Gustav Carus University Medical School, University of Technology, Dresden, Germany.
In 2013, Magda Santana got her Doctoral degree in Pharmacy at the University of Coimbra, Portugal.  Magda Santana has international scientific experience acquired as undergraduate student, being enrolled in the Erasmus Program (Pharmaceutical and Biological Chemistry Department, School of Pharmacy, London, UK) and as PhD student (Dresden, Germany).  
Since 2013 until present, Magda Santana is a postdoctoral researcher at Center for Neuroscience and Cell Biology, being responsible for the development of pre-clinical studies.



Area of Research: 

Neuroscience Translational Research; Pre-clinical development; Pre-clinical models of disease; Stress, Aging and related diseases

Research Summary:
Selected Publications: 

Santana MM, Rosmaninho-Salgado J, Cortez V, Pereira FC, Kaster MP, Aveleira CA, Ferreira M, Alvaro AR, Cavadas C. Impaired adrenal medullary function in a mouse model of  depression induced by chronic unpredictable stress. Eur Neuropsychopharmacol. 2015 Jul 2. [In press; Impact factor.4.37]

Kaster MP, Machado NJ, Silva BH, Nunes A, Ardais AP, Santana MM, Baqi Y, Müller CE, Rodrigues AL, Porciúncula LO, Chen JF, Tomé AR, Agostinho PM, Canas PM, Cunha RA. Neuronal adenosine A2A receptors control behavioral and synaptic dysfunction triggered by chronic unpredictable stress. Proc Natl Acad Sci U S A. 2015 Jun 23;112(25):7833-8. (Impact factor: 9.67)

Aveleira CA, Botelho M, Carmo-Silva S, Pascoal JF, Ferreira-Marques M, Nóbrega C, Cortes L, Valero J, SousaFerreira L, Álvaro RA, Santana M, Kügler S, Pereira-de-Almeida L, Cavadas C. Neuropeptide Y stimulates autophagy in hypothalamic neurons. Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):E1642-51 (Impact factor: 9.67)

Santana MM, Chung KF, Vukicevic V, Rosmaninho-Salgado J, Kanczkowski W, Cortez V, Hackmann K, Bastos CA, Mota A, Schrock E, Bornstein SR, Cavadas C, Ehrhart-Bornstein M. Isolation, characterization and differentiation of progenitor cells from human adult adrenal medulla. Stem Cells Transl Med. 2012 Nov;1(11):783-91 (Impact factor: 5.71)

Sousa-Ferreira L, Álvaro AR, Aveleira C, Santana M, Brandão I, Kügler S, de Almeida LP, Cavadas C. Proliferative hypothalamic neurospheres express NPY, AGRP, POMC, CART and Orexin-A and differentiate to functional neurons. PloS One. 2011 May 11;6(5):e19745. (Impact factor: 3.23)

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