Lígia Sousa-Ferreira
239 820 190 
Post-doctoral researcher
Group at CNC

Lígia Sousa-Ferreira got her degree in Pharmaceutical Sciences in 2006 at the Faculty of Pharmacy, University of Coimbra, Portugal.
In 2006, she got a FCT PhD Fellowship to develop her PhD research with the project entitled “Modulation of Neuropeptide Y in the adult hypothalamus and hypothalamic progenitor cells: Effects on feeding behavior and neuropeptides regulation”. This work was developed at the Center for Neuroscience and Cell Biology (Group of Vectors and Gene Therapy and Group of Neuroendocrinology and Aging), University of Coimbra, Portugal, and at the Viral Vector Laboratory at the University of Göttingen, Germany.
Lígia got her PhD degree in Pharmacology at Faculty of Pharmacy, University of Coimbra, in 2011.
Currently, she is a postdoctoral researcher at Center for Neuroscience and Cell Biology, University of Coimbra and was granted with a FCT Post-Doc fellowship to study the involvement of microRNAs in food intake and obesity.




Area of Research: 

- Hypothalamus and feeding regulation;
- Obesity and aging;
- Endocrinology and Metabolism
- Neurogenesis;
- MicroRNAs and gene delivery

Research Summary: 
Selected Publications: 

L. Sousa-Ferreira, L. Pereira de Almeida, C. Cavadas; “Role of hypothalamic neurogenesis in feeding regulation”; Trends in Endocrinology and Metabolism, 25 (2), 80-8, 2014. (IF=9.4)
L. Sousa-Ferreira, M. Garrido, I. Nascimento-Ferreira, C. Nobrega, A. Santos-Carvalho, A.R. Álvaro, J. Rosmaninho-Salgado, M. Kaster, S. Kügler, L. Pereira de Almeida, C. Cavadas. “Moderate long-term modulation of Neuropeptide Y in the Arcuate Nucleus induces energy balance alterations in adult rats”; PLoS One 6(7):e22333, 2011. (IF=3.7)
L. Sousa-Ferreira, A.R. Álvaro, C. Aveleira, M. Santana, I. Brandão, S. Kügler, L. Pereira de Almeida, C. Cavadas; “Proliferative hypothalamic neurospheres express NPY, AGRP, POMC, CART and Orexin-A and differentiate to functional neurons expressing appetite-related neuropeptides”; PLoS One 6(5):e19745, 2011 . (IF=3.7)
L. Sousa-Ferreira, C. Aveleira, M. Botelho, A. R. Álvaro, L. Pereira de Almeida, C. Cavadas; “Fluoxetine induces proliferation and inhibits differentiation of hypothalamic neuroprogenitor cells mediating alterations in appetite neuropeptides levels” ; PLoS One 9(3):e88917, 2014. (IF=3.7)
C. Aveleira, M. Botelho, S. Carmo-Silva, J. Pascoal, M. Ferreira-Marques, C. Nóbrega, L. Cortes, J. Valero, L. Sousa-Ferreira, A. R. Álvaro, M. Santana, S. Kügler, L.Pereira de Almeida, C. Cavadas; “Neuropeptide Y stimulates autophagy in hypothalamic neurons”; PNAS, 112(13), 2015. (IF=9.674)

Other information: 


Financiado por Fundos FEDER através do Programa Operacional Factores de Competitividade – COMPETE 2020 e por Fundos Nacionais através da FCT – Fundação para a Ciência e a Tecnologia no âmbito do projecto Estratégico com referência atribuida pelo COMPETE: POCI-01-0145-FEDER-007440

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