Ângela Valério-Fernandes (Valério-Fernandes, Â.)
239 820190
PhD student
Group at CNC

I am graduated in Biology-scientific field from the University of Trás-os-Montes e Alto Douro (UTAD).
I obtained a MSc degree in Legal Medicine from the Institute of Biomedical Sciences Abel Salazar (ICBAS), University of Oporto.
Currently, I am Ph.D student from the Doctoral Program of Experimental Biology and Biomedicine (PDBEB) in the field of Nanomedicine and Oncobiology, in Vectors and Gene Therapy Group at the Centre for Neurosciences and Cell Biology (CNBC), University of Coimbra, under the supervision of Professor Doctor João Nuno Moreira and Professor Sérgio Simões.



Area of Research: 

Translational Medicine, Oncobiology, Cancer Cellular therapy, Nanomedicine, Pharmaceutical biotechnology

Research Summary: 
Selected Publications: 

1.    Fonseca, Nuno A.; Rodrigues, Ana S.; Rodrigues-Santos, Paulo; Alves, Vera; Gregório, Ana C.; Valério-Fernandes, Ângela; Gomes-da-Silva, Lígia C.; Rosa, Manuel Santos; Moura, Vera; Ramalho-Santos, João; Simões, Sérgio; Moreira, João Nuno. Nucleolin overexpression in breast cancer cell sub-populations with different stem-like phenotype enables targeted intracellular delivery of synergistic drug combination. Biomaterials, v. 69, n.  -, p. 76-88, 2015. (IF: 9.3)

2.    Fonseca, Nuno A.; Gregório, Ana C.; Valério-Fernandes, Ângela; Simões, Sérgio; Moreira, João N. Bridging cancer biology and the patients' needs with nanotechnology-based approaches. Cancer Treatment Reviews, v. 40, n. 5, p. 626-635, 2014. (IF: 7.6)

3.    Valério-Fernandes, A.; Fonseca, N.; Moura, V.; Ladeirinha, A.; Ferreira, T.; Alarcão, A.; Carvalho, L.; Simões, S.; Moreira, J.N. 600: Targeting nucleolin in lung cancer - an emerging strategy to overcome stroma-mediated anti-VEGF resistance. European Journal of Cancer, v. 50, n.  -, p. S145-S145, 2014.

4.    Valério-Fernandes, Â.; Fonseca, Nuno A.; Moura, Vera; Ladeirinha, A.; Ferreira, T.; Alarcão, A.; Carvalho, L.; Simões, Sérgio; Moreira, João Nuno. Targeting nucleolin: A potential strategy to overcome stroma-mediated bevacizumab resistance in lung cancer. The Journal of Cancer Research - AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA, n. 64, p. 1-2, 2013.

5.    Lemos, Cristina; Valério-Fernandes, Ângela; Ghisleni, Gabriele C.; Ferreira, Samira G.; Ledent, Catherine; de Ceballos, María L.; Köfalvi, Attila. Impaired hippocampal glucoregulation in the cannabinoid CB1 receptor knockout mice as revealed by an optimized in vitro experimental approach. Journal of Neuroscience Methods, v. 204, n. 2, p. 366-373, 2012.

Other information: 
Financiado por Fundos FEDER através do Programa Operacional Factores de Competitividade – COMPETE 2020 e por Fundos Nacionais através da FCT – Fundação para a Ciência e a Tecnologia no âmbito do projecto Estratégico com referência atribuida pelo COMPETE: POCI-01-0145-FEDER-007440

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