Lipids under stress
2016.6.30
Tiago Oliveira Life and Health Sciences Research Institute (ICVS), University of Minho, Braga
14:00h
CNC Auditorium (2nd floor)
University of Coimbra, POLO I
Host: Ana Cristina Rego


“Lipids under stress”
 
The emerging field of lipidomics has identified lipids as key players in disease physiology. Their physicochemical diversity allows precise control of cell structure and signaling events through modulation of membrane properties and trafficking of proteins. As such, lipids are important regulators of brain function and have been implicated in neurodegenerative and mood disorders. Importantly, environmental chronic stress has been associated with anxiety and depression and its exposure in rodents has been extensively used as a model to study these diseases. With the accessibility to modern mass-spectrometry lipidomic platforms, it is now possible to snapshot the extensively interconnected lipid network. Thus, lipid profiling provides an exciting avenue for the identification of disease signatures with important implications for diagnosis and treatment of mood disorders
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Funded by ERDF - European Regional Development Fund through COMPETE 2020 and National Funds via FCT - Fundação para a Ciência e Tecnologia, under projects POCI-01-0145-FEDER-007440 e UIDB/04539/2020.

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