CNC Internal Newsletter
Issue 5 | November 2017
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Publications October | November

Medial Frontal Lobe Neurochemistry in Autism Spectrum Disorder is Marked by Reduced N-Acetylaspartate and Unchanged Gamma-Aminobutyric Acid and Glutamate + Glutamine Levels.
Carvalho Pereira A, et al. J Autism Dev Disord. 2017 Nov 24

Intracellular delivery of more than one protein with spatio-temporal control.
Lino MM, et al. Nanoscale. 2017 Nov 22.

Disruption of mitochondrial function as mechanism for anti-cancer activity of a novel mitochondriotropic menadione derivative.
Teixeira J, et al. Toxicology. 2017 Nov 12

IWR-1, a tankyrase inhibitor, attenuates Wnt/β-catenin signaling in cancer stem-like cells and inhibits in vivo the growth of a subcutaneous human osteosarcoma xenograft.
Martins-Neves SR, et al. Cancer Lett. 2017 Nov 8

The Use of Repetitive Transcranial Magnetic Stimulation for Stroke Rehabilitation: A Systematic Review.
Dionísio A, et al. J Stroke Cerebrovasc Dis. 2017 Oct 27




Lipophilic Fraction of Cultivated Bifurcaria bifurcata R. Ross: Detailed Composition and In Vitro Prospection of Current Challenging Bioactive Properties.
Santos SAO, et al. Mar Drugs. 2017 Nov 1

Combination of Anti-miRNAs Oligonucleotides with Low Amounts of Chemotherapeutic Agents for Pancreatic Cancer Therapy.
Passadouro M, Faneca H. Methods Mol Biol. 2017 Oct 31

The Influence of Adipose Tissue on Brain Development, Cognition, and Risk of Neurodegenerative Disorders.
Letra L, Santana I. Adv Neurobiol. 2017

Combination of Poly[(2-dimethylamino)ethyl methacrylate] and Poly(β-amino ester) Results in a Strong and Synergistic Transfection Activity.
Santo D, et al. Biomacromolecules. 2017 Oct 9


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Awards / Honors
International funding from Richard Chin and Lily Lock fund [see here]
Luís Pereira de Almeida’s group – Research on Machado-Joseph disease

Awards PhD Transition Fellowships [see here] (foto)
Sara Lopes e Patrícia Albuquerque (3rd award)

Award Thomé Villar/Boehringer Ingelheim 2017 from the Portuguese Society of Pneumonoly
Nuno Empadinhas – Research on the “Prevalence and Genetic Variability of Non-tuberculosis Mycotherapies in Domestic Environment”

International funding from Richard Chin and Lily Lock fund
Awards PhD Transition Fellowships
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Scientific Meetings and Events

“Ciência, Saúde e Comunicação” Meeting | 24 November 2017, Porto (Portugal)
CNC representation by João Ramalho-Santos, Sara Amaral and Ana Teresa Viegas

“Jornadas Cannadouro” | 18 – 19 November 2017, Porto (Portugal) [see here]
Participation of Atilla Kofalvi

XXXIII Congresso de Pneumonologia | 9 – 11, Albufeira (Portugal) [see here]
Participation of Nuno Empadinhas

“Ciência, Saúde e Comunicação” Meeting
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Public Engagement in Science

Semana da Ciência e Tecnologia | 14 – 24 November, Coimbra (Portugal) [see here]

“Diabetic Journeys” – Comics about Diabetes published in Público newspaper [see here]

Open Labs – Visits from students to CNC labs

Visits to schools – Hands-on activities with the students

Workshop for high-school teachers “A aprendizagem das células: Biologia Reprodutiva e Células Estaminais” (2nd edition)

2nd PubhD Coimbra | 23 November, Aqui Base Tango, Coimbra (Portugal) [see here]
Participation of João Silva – “Metabolismo”


“Diabetic Journeys”

Semana da Ciência e Tecnologia 2017 at the University of Trás-os-Montes and Alto Douro | 21 November 2017, Vila Real (Portugal)

Participation of Paulo Oliveira – “Mitochondrial Alterations in Non-alcoholic Fatty Liver Disease: A Tale of (Bad) Nutrition and Batteries”.


Reception of the event “Paisagens Neurológicas – arte & ciência” | 11 November, CNC, Coimbra (Portugal) [see here]

The Science Communication Office would like to thank everyone who have been involved in our activities.


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Visit to Schools
Workshop for high-school teachers
2nd PubhD Coimbra
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CNC on the Media

• News about the work coordinated by Ricardo Vieira-Pires. [see here]

• News about the funding received by Luís Pereira de Almeida’s team from the international fund Richard Chin and Lily Lock. [see here]

• Interview with Sara Amaral about Semana da Ciência e Tecnologia 2017 on RUC (Rádio Universidade de Coimbra. [see here]

• News about the international project coordinated by Lino Ferreira. The news can be found here and the paper here.

Work coordinated by Ricardo Vieira-Pires
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New faces | New roles

Marie Babková
Master’s student
Neuroendocrinology and Aging Group
José Pedro Sampaio
Master’s student
Neuronal Circuits and Behavior
Pedro António
Master’s student
Neuronal Circuits and Behavior Group
Catarina Seabra
Post-doctoral Research Fellow
Neuronal Circuits and Behavior Group
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Don’t miss out

Happy Birthday to us! On the 26th November we completed 27 years of scientific research. Watch here the video about CNC.

We invite you to fill out the Google Form to allow for the gathering of information regarding the CNC’s community. Please click here.

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27th Meeting Digest
• Discussion about the FCT Evaluation of Research Units for 2018 (call: January 31st) – Meeting with PI’s on November 29th.

• Announcement of the date of 2nd Meeting on Biomedical Research @ UC will take place December 21st at Pólo III Auditorium, University of Coimbra.
Registration until December 14th to Susana Rocha (
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Get Involved
CNC Seminars
Fall Series - Next talks

@CNC / UC-Biotech, Cantanhede

"Unexpected phenotypic variability of parasites occupying the adipose tissue"
Luísa Figueiredo (IMM, University of Lisbon)
Host: Ana Eulálio
December 6

“At the heart of stem cells in Regeneration and Repair”
Perpétua Pinto-do-Ó (I3S/INEB and ICBAS, University of Porto)
Host: Miguel Mano
December 13

@CNC, Pólo I, Coimbra

“Meet the Industry 3: Coimbra Genomics”
Bruno Soares (Coimbra Genomics)
Host: Ana Catarina Gomes
December 7

• “Proteasis and mitochondrial function in human epicardial adipose tissue”
Ana Catarina Fonseca (CNC, Coimbra)
Host: Ana Burgeiro
December 15


PDBEB Advanced Courses 2017/2018 [see here]

Core Facilities
December 4
Coordinators: Luísa Cortes, Isabel Nunes, Conceição Egas

January 8 -19

Connecting the Researchers with the society
January 22 – 26
Science Communication Office

Let us know if you have more informations or any suggestions, to improve "Synergies"


Science Communication Office | Ana Teresa Viegas, Sara Varela Amaral, Adalberto Fernandes, Claudia Cavadas (Coordinator)
Design and Layout:

Lia Lopes and Ana Sofia Mergulhão