CNC Internal Newsletter
Issue 9 | March 2018
 
  Publications February | March

Efficacy Analysis of Capsaicin 8% Patch in Neuropathic Peripheral Pain Treatment.
Tenreiro Pinto J, et al. Pharmacology. 2018 Mar 27

Adenosine A2A receptors modulate the dopamine D2 receptor-mediated inhibition of synaptic transmission in the mouse prefrontal cortex.
Real JI, et al. Eur J Neurosci. 2018 Mar 23

Cell-autonomous and cell non-autonomous downregulation of tumor suppressor DAB2IP by microRNA-149-3p promotes aggressiveness of cancer cells.
Bellazzo A, et al. Cell Death Differ. 2018 Mar 22

Sweet Mitochondria: A Shortcut to Alzheimer's Disease.
Moreira PI. J Alzheimers Dis. 2018

Mitochondrial Biology and Experimental Therapeutics
Oliveira, Paulo J. (editor). Springer. 2018 Mar 21

MiR-16 regulates the pro-tumorigenic potential of lung fibroblasts through the inhibition of HGF production in an FGFR-1- and MEK1-dependent manner.
Andriani F, et al. J Hematol Oncol. 2018 Mar 20

Hexavalent chromium, a lung carcinogen, confers resistance to thermal stress and interferes with heat shock protein expression in human bronchial epithelial cells.
Abreu PL, et al. Biometals. 2018 Mar 16

Data.
Ramalho-Santos J. Nature. 2018 Mar 15

 

 

CYP2D6 Pharmacogenetics Testing and Post-Cesarean Section Pain Scores-a Preliminary Study.
Ribeiro C, et al. Pain Med. 2018 Mar 12

Considerations and Pitfalls in Selecting the Drug Vehicles for Evaluation of New Drug Candidates: Focus on in vivo Pharmaco-Toxicological Assays Based on the Rotarod Performance Test.
Matias M, et al. J Pharm Pharm Sci. 2018

Release kinetics and cell viability of ibuprofen nanocrystals produced by melt-emulsification.
Fernandes AR, et al. Colloids Surf B Biointerfaces. 2018 Mar 5

In silico studies targeting G-protein coupled receptors for drug research against Parkinson's disease.
Lemos A, et al. Curr Neuropharmacol. 2018 Mar 8

Intravenous administration of retinoic acid-loaded polymeric nanoparticles prevents ischemic injury in the immature brain.
Machado-Pereira M, et al. Neurosci Lett. 2018 Mar 5

MicroRNA-124-loaded nanoparticles increase survival and neuronal differentiation of neural stem cells in vitro but do not contribute to stroke outcome in vivo.
Saraiva C, et al. PLoS One. 2018 Mar 1

Novel Tacrine-Hydroxyphenylbenzimidazole hybrids as potential multitarget drug candidates for Alzheimer's disease.
Hiremathad A, et al. Eur J Med Chem. 2018 Mar 25

 

 

 

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Awards / Honors

Best Oral Communication in Basic Research | 14º Congresso Português de Diabetes | 11 March, 2018 [see here]

Susana P. Pereira – Mitochondrial Toxicology and Experimental Therapeutics Group (P.I.: Paulo Oliveira)
Title: “Diabetes e doença cardíaca: uma herança da vida intrauterina?”

S.P. Pereira, M. Nijland, L. Tavares, A. Duarte, I. Baldeiras, T. Cunha-Oliveira, M. Santos, A. Moreno, L. Cox, P. Nathanielsz e P. Oliveira



Travel Grant to participate in the 52nd Annual Scientific Meeting of the European Society for Clinical Investigation – “Precision medicine for healthy ageing” | 30 May – 1 June, 2018, Barcelona, Spain [see here]

Tiffany Pinho – Metabolism, Aging and Disease – Cell Metabolism and Quality Control Group (P.I.: Paula I. Moreira)

Best Oral Communication in Basic Research
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Events @ CNC
11st Beer for Thought | 1 March 2018, CNC, Coimbra 2018

11st Beer for Thought
Let us know if you have more information to add to this section.
Scientific Meetings and Events


Biomedical Research: Post-Doctoral Forum @UC – “Overcoming Challenges in Scientific Research” 2018 | 23 March, 2018, Faculty of Medicine of University of Coimbra (Pólo III), Coimbra, Portugal
Organized by CNC and IBILI post-doctoral researchers.


Meet.Lab Coimbra | 3 March, 2018, Departamento Ciências da Vida, University of Coimbra, Coimbra, Portugal
Participation of:

- Ana Rita Álvaro - “Acertar o ritmo biológico para parar o tempo" (oral communication)

- Carlos Matos - “Edição génica em doenças neurodegenerativas” (oral communication)

- Nuno Empadinhas - “Viver com os micróbios: resistências a antibióticos e microbioma humano” (oral communication)

- Alexandra Carvalho - "Criopreservação de Gâmetas e Tecido Gonadal" (workshop)

- Renata Tavares - "Avaliação da Qualidade Seminal & Estratégias Contracetivas" (workshop)

- Sara Amaral - “Comunicação Científica” (workshop)



Biomedical Research: Post-Doctoral Forum @UC
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Public Engagement in Science

• Brain Awareness Week | 1 – 30 March, 2018

o Neuroaventuras no Laboratório – Open Labs

o Neuroaventuras nas Escolas – Researchers’ visits to kindergartens, elementary, middle and high schools, associations, seniors’ centers and universities (Photo by Tiffany Pinho)

o Official Inauguration of the MicroScience Photo Gallery – “The Beauty in Our Cells” | 13 March – Exploratório CCV Coimbra

o 7th PubhD Coimbra | 22 February, Aqui Base Tango, Coimbra, Portugal
- Participation of Laetitia Gaspar

o Dormir será uma perda de tempo? - Dia Mundial do Sono | 16 March, Exploratório CCV, Coimbra, Portugal
- Participation of Ana Rita Álvaro

o Demência e Stress – Public event | 18 March, Fnac – Fórum Coimbra
- Moderated by Cristina Rego


o Brain Buskers | Jardim Botânico - Postponed event due to weather conditions. More information coming soon

o Selfie Science – Lunch of monthly videos
- David Ramos [see here]
- Tiffany Pinho [see here]
- Dominique Fernandes [see here]
- Ana Rita Álvaro [see here]
- Tiago Reis (José Pedro Sampaio collaboration) [see here]

Special thanks to Tiago Reis for video editing.

Let us know if you are interested in participating in the next editions.

The Science Communication Office would like to thank all the CNC members who participated in these initiatives.

Neuroaventuras no Laboratório
Neuroaventuras nas Escolas
Official Inauguration of the MicroScience Photo Gallery
Selfie Science

• Cafés com Ciência | 27 March, Sertã, Portugal [see here]
Participation of Cláudia Cavadas – “À procura do elixir da juventude?”

• Ciência às Seis | 21 March, Rómulo – Centro de Ciência Viva, University of Coimbra, Portugal
Participation of Manuela Grazina – “Doenças Raras: acordar, pestanejar e as avarias das fábricas de energia”.

• FameLab Portugal – Semi-final | 18 March, Pavilhão do Conhecimento – Centro de Ciência Viva, Lisboa, Portugal
Participation of Ricardo Neves and João Cardoso (national finalists)
Final: 12 April | Coliseu dos Recreios, Lisbon, Portugal

• Talk “ALTA VOLTAGEM ou Histórias da Mitocôndria” | 16 March, Escola Secundária D. Duarte, Coimbra, Portugal | Paulo Oliveira

• International Women Day | 8 March, Pavilhão do Conhecimento – Centro de Ciência Viva, Lisbon, Portugal | Participation of Cláudia Cavadas

7th PubhD Coimbra
 
Demência e Stress
 
FameLab Portugal – Semi-final
Let us know if you have more information to add to this section.
CNC on the Media

• News about genetic alterations of CYP2D6 enzyme and a new medical approach for a personalized treatment of post-cesarean pain – research from the Genetic Biochemistry Laboratory

o Postal [see here] | 28 March

o ElvasNews [see here] | 24 March

o Notícias de Viseu [see here] | 24 March

o Campeão das Províncias – Column “Figuras da Semana” – Manuela Grazina | 22 March

o Boas Notícias [see here] | 22 March

o Rua Direira [see here] | 20 March

o Atlas da Saúde [see here] | 19 March

o Beira News [see here] | 19 March

o Campeão das Pronvíncias [see here] | 19 March

o Green Savers [see here] | 19 March

o Jornal É Notícia [see here] | 19 March

o Mood Magazine [see here] | 19 March

o Notícias de Coimbra [see here] | 19 March

o Saúde Online [see here] | 19 March


• Interview with Luís Pereira de Almeida about Machado-Joseph disease
o Sábado (in press) | 28 March


• News about the Marie-Curie Fellowship won by Catarina Seabra

o Diário dos Açores (in press) | 27 March

o VerPortugal [see here] | 24 March

o Alert [see here] | 23 March

o Diário as Beiras (in press) | 23 March

o Diário de Coimbra (in press) | 22 March

o Diário de Leiria (in press) | 22 March

o i9 Magazine [see here] | 22 March

o Público [see here] | 22 March

o Rua Direita [see here] | 22 March

o Índice.eu [see here] | 22 March

o AEIOU [see here] | 21 March

o Atlas da Saúde [see here] | 21 March

o Campeão das Províncias [see here] | 21 March

o Destak [see here] | 21 March

o Diário de Notícias [see here] | 21 March

o Douro Hoje (in press) | 21 March

o Expresso [see here] | 21 March

o Figueira TV [see here] | 21 March

o Green Savers [see here] | 21 March

o Impala [see here] | 21 March

o JM [see here] | 21 March

o Jornal É Notícia [see here] | 21 March

o Notícias ao Minuto [see here] | 21 March

o Notícias de Coimbra [see here] | 21 March

o Notícias Saúde [see here] | 21 March

o Observador [see here] | 21 March

o Pontos de Vista [see here] | 21 March

o Porto Canal [see here] | 21 March

o PT Jornal [see here] | 21 March

o RTP [see here] | 21 March

o Sapo 24 [see here] | 21 March

o Sapo Lifestyle [see here] | 21 March

o Terras de Sicó [see here] | 21 March

o TSF [see here] | 21 March

o TV Europa [see here] | 21 March

o TVI 24 [see here] | 21 March

o Visão [see here] | 21 March

o Diário dos Açores (in press) | 20 March

o Plus 40 news in the Spanish media


• News about World Sleep Day (collaboration with Associação Portuguesa do Sono):

o Ovar News [see here] | 25 March

o Raio X [see here] | 22 and 19 March

o Diário as Beiras [see here] | 19 and 17 March

o AEIOU [see here] | 19 March

o TVI – TV show “A Tarde é Sua” - interview with Ana Rita Álvaro [see here – @1:06:41] | 16 March

o A Bola [see here] | 16 March

o Observador [see here] | 16 March

o Público (in press and online) [see here and here] | 16 March

o Lunch of the Science Communication comics “Viagens sem Insónias” [see here] | 16 March

o Sapo Lifestyle [see here] | 16 March

o Sábado [see here] | 16 March

o BeiraNews [see here] | 16 March

o NewsPharma [see here] | 16 March

o Notícias de Vouzela (in press) | 15 March

o Índice.eu [see here] | 14 March

o Atlas Saúde [see here] | 13 March

o Vital Health [see here] | 13 March


• Interview with João Ramalho-Santos about CNC research and science communication activities

o Diário as Beiras (in press) | 24 March


• News about the inauguration of the MicroScience Photo Gallery “The Beauty in Our Cells”

o Diário as Beiras (in press) | 14, 13 and 12 March

o Diário de Coimbra (in press) | 14 and 12 March

o AuriNegra [see here] | 13 March


• News about Brain Awareness Week activities

o A Cabra [see here] | 13 March

o Campeão das Províncias [see here] | 13 March

o BeiraNews [see here] | 11 March

o Diário de Coimbra (in press) | 11 March

o Rua Direita [see here] | 11 March

o Diário as Berias (in press) | 10 March

• News about the internships in collaboration with IEC (Instituto de Educação e Cidadania)

o Jornal da Bairrada (in press) | 1 March
Let us know if you have more information to add to this section.
Opportunities
Research Grants:

One Post-Doctoral Position at MCG [see here]

Senior Scientist or Associate Scientist or Assistant Scientist at University of Wisconsin-Madison [see here]

Lecturer, Kinesiology, University of Massachusetts-Amherst [see here]

Posdoctoral Fellow Position in Johns Hopkins University [see here]




 
Let us know if you have more information to add to this section.
Don’t miss out

FameLab Portugal – International Science Communication Competition [see here]

o 12 April – National Final at Coliseu dos Recreios, Lisbon, Portugal
The Science Communication Office would like to thank the researchers who participated in this competition.
(foto 13)



GPS (Global Portuguese Scientists) – Online Network that connects Portuguese researchers around the world [see here]

The Science Communication Office would like to encourage the researchers to join this online scientific network.

 

FameLab Portugal
• Brain Buskers

Project financed by the Biochemical Society (UK).


The Science Communication Office would like to encourage the researchers to join us in this initiative.
Let us know if you have more information to add to this section.
PhD Defenses
 
 
Mariline Silva | 6 March, 2018
Thesis: "Unveiling the role of miRNAs in synaptic plasticity.”
Supervisors: Ana Luísa Carvalho (Faculdade de Ciências e Tecnologia, Universidade de Coimbra)
 
 
Let us know if you have more information to add to this section.
 
Get Involved
CNC Seminars
Winter Series - Next talks

@CNC, UC - Pólo I, Coimbra – 14h

• “Visual binding: how brain oscillations shape perception”
Gabriel Costa (IBILI and CIBIT, University of Coimbra)
Host: Emília Duarte
April 6

• “DNA methylation players in memory formation”
Ana M. M. Oliveira (Interdisciplinary Center for Neurosciences, University of Heidelberg, Germany)
Host: Carlos B. Duarte
April 13

• “Principled views on synapses and circuits: statistical and deep learning”
Rui Ponte Costa (Department of Physiology, Anatomy and Genetics, University of Oxford, UK and Department of Physiology, University of Bern, Switzerland)
Host: Carlos B. Duarte
April 13 (15h30)


@CNC / UC-Biotech, Cantanhede – 11h30

• “Impaired neural development restricts organism recovery upon reversible loss of cohesion and consequent aneuploidy”
Leonardo Gaston Guilgur (IGC, Oeiras)
Host: John Jones
April 4

• To be announced
Marta Mendes (IBMC/i3S, University of Porto)
Host: Ricardo Pires
April 11

• “Mitochondrial and lysosomes – a fight for power”
Nuno Raimundo (Institute of Cellular Biochemistry, University Medical Center Goettingen, Germany)
Host: Paulo Oliveira
April 12 (Thursday)

• “Linking obesity and cancer through angiogenesis”
Raquel Soares (i3S and Faculty of Medicine, University of Porto)
Host: Armindo Salvador
April 18




PDBEB Advanced Courses 2017/2018 [see here]




Synapses, Neuronal Circuits and Behavior - Supported by FENS/IBRO-PERC
April 9 - 20, 2018
FENS and IBRO-PERC provides 4 stipends of 750 EUR for master and/or PhD students interested in attending this course.


Neurodegenerative disorders
April 23 - 27, 2018


Advanced Therapies
May 7 - 11, 2018


Drug Development
May 21 - June 1, 2018


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Let us know if you have more informations or any suggestions, to improve "Synergies"
Credits

Contents:

Science Communication Office | Ana Teresa Viegas, Sara Varela Amaral, Adalberto Fernandes, Claudia Cavadas (Coordinator)
Design and Layout:

Lia Lopes and Ana Sofia Mergulhão