CNC Internal Newsletter
Issue 11 | May 2018
  Publications April | May

O-GlcNAcylation and neuronal energy status: implications for Alzheimer's disease.
Pinho TS, et al. Ageing Res Rev. 2018 May 19

In vitro susceptibility of Trypanosoma brucei brucei to selected essential oils and their major components.
Costa S, et al. Exp Parasitol. 2018 May 17

Analysis of respiratory capacity in brain tissue preparations: high-resolution respirometry for intact hippocampal slices.
Dias C, et al. Anal Biochem. 2018 May 17

Anticancer activity and antibody-dependent cell-mediated cytotoxicity of novel anti-nucleolin antibodies.
Romano S, et al. Sci Rep. 2018 May 10






Osmotic modulation of chromatin impacts on efficiency and kinetics of cell fate modulation.
Lima AF, et al. Sci Rep. 2018 May 8

Repurposing drugs for glioblastoma: From bench to bedside.
Basso J, et al. Cancer Lett. 2018 May 3

Meeting the needs of breast cancer: A nucleolin's perspective.
Gregório AC, Lacerda M, Figueiredo P, Simões S, Dias S, Moreira JN.
Crit Rev Oncol Hematol. 2018 May






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Awards / Honors

Science Flash Contest (European Molecular Biology Laboratory – EMBL) – 3rd prize | May 16
Fábio Sousa (Watch here Fábio’s video about his work in Alzheimer’s disease)

Janssen Innovation Award – 2nd prize | May 9, Porto, Portugal
Sara Carmo Silva, Clévio Nóbrega, Marisa Ferreira-Marques, Mariana Botelho, Célia A. Aveleira, Cláudia Cavadas (Neuroendrocrinology and Aging Group, CNC) and Luís Pereira de Almeida (Vectos and Gene Therapy, CNC) in collaboration with Clévio Nóbrega (CBMR – Centre for Bio-Medical Research, UAlg)

Assembly of National Sleep Societies – 2nd prize | May 4-5, Parma, Italy
World Sleep Day Project - Associação Portuguesa do Sono and CNC partnership (activities: Comics “Viagens sem Insónia”, PubhD Coimbra (6th edition) and talk “Dormir é uma perda de tempo?” at Exploratório – CCV)

EIT Wild Card Tournament | April 16-20, Galway, Ireland
Ricardo Vieira-Pires (listed in the 30 selected finalists)

Janssen Innovation Award – 2nd prize
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Events @ CNC

• 13th Beer for Thought | May 17th, UC-Biotech Gardens, Cantanhede
13th Beer for Thought
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Scientific Meetings and Events

20th European Testis Workshop (ETW Portugal) | May 24-27, Praia D’El Rey, Óbidos, Portugal
o Organized by the “Biology of Reproduction and Stem Cells” CNC group

EIT Wild Card Tournament | April 16-20, Galway, Ireland
o Participartion of Ricardo Vieira-Pires
Read Ricardo’s opinion article on LinkedIn [see here]

EIT Wild Card Tournament

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Public Engagement in Science

Selfie Science | 30 May
Ana Filipa Cruz [see here]

A special thanks to Tiago Reis for the video editing.

Conversas Sistemáticas | May 2, Rómulo Centro de Ciência Viva, Coimbra
Ana Luísa Cardoso

Brain Buskers

Queima das Fitas, Coimbra | May 10
o Ana Teresa Viegas, Bibiana Silva, João Calmeiro, João Cardoso, Marcos Gomes, Mariana Laranjo, Marta Pereira, Sara Amaral, Tiago Reis and Tiffany Pinho

Jardim Botânico, Coimbra
| May 11
o Ana Teresa Viegas, Catarina Seabra, Fábio Sousa, Ricardo Moreira, Rita Amado Dias, Mireia Alemany, Sara Amaral

Teatro Académico Gil Vicente (TAGV), Coimbra | May 29
o Ana Rita Jesus, Bibiana Silva, Fábio Sousa, João Cardoso, Rita Amado, Tiago Reis)

Selfie Science
Conversas Sistemáticas
Brain Buskers - Jardim Botânico
Brain Buskers - Queima das Fitas
Brain Buskers - TAGV
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CNC on the Media

• News about the Janssen Innovation Award (2nd prize)
o Rádio Universidade de Coimbra | May 24
Interview with Sara Carmo Silva and Cláudia Cavadas

• News about Manifesto Ciência Portugal 2018 signed by several researchers, including João Ramalho Santos
o Expresso | May 22 [see here]

• News about the 20th European Testis Workshop (ETW) taking place in Portugal and organized by the Biology of Reproduction and Stem Cells group.
o Diário as Beiras | May 21 (in press)
o Rua Direita | May 22 [see here]
o Beira News | May 22 [see here]
o Diário de Coimbra | May 23 (in press)

• News about the scientific innovation schoolarships awarded to the Laboratory of Biochemical Genetics
o Campeão das Províncias | May 14 [see here]
o Diário As Beiras | May 16 (in press)

• News about CNC research regarding Photodynamic Therapy in the treatment of dental infections (Medical Microbiology group - P.I.: Teresa Gonçalves)
o PT Jornal | May 14 [see here]
o Postal do Algarve | May 14 [see here]
o Notícias de Coimbra | May 14 [see here]
o Jornal É Notícia | May 14 [see here]
o Jornal Dentistry | May 14 [see here]
o Boas Notícias | May 14 [see here]
o Beira News | May 14 [see here]
o AuriNegra | May 14 [see here]
o GreenSavers | May 15 [see here]
o Campeão das Províncias | May 17 (in press)

• Patrícia Diogo in “Figuras da Semana” column
o Tribuna da Madeira | May 18 (in press)

• Article about gene therapy approaches – Interview with Luís Pereira de Almeida
o Sábado | May 3 [see here]

• Interview with Catarina Seabra about the ProTeAn project and Marie Sktodowska-Curie Individual Fellowship
o “Mentes que Brilham” in Porto Canal | May 1 [see here]
o “Ciência” in Antena 2 | May 14 [see here]

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Research Opportunities:

One Postdoctoral Position at CNC:
o Cell Reprogramming and Developmental Hematopoiesis Research Group, at UC-Biotech in Cantanhede [see here]
Interested candidates should email CV, motivation letter and the contacts of 2 references to Filipe Pereira:

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New Faces | New Roles
Emanuel Melo
Science and Technology Management
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Don’t miss out

Rotors inspection day – Check the condition of your rotors with the Technical Service of Izasa Scientific | June 6 at 10am – Pólo I - CNC Auditorium (2nd floor)

GPS (Global Portuguese Scientists) – Online Network that connects Portuguese researchers around the world [see here]

The Science Communication Office would like to encourage the researchers to join this online scientific network.


Let us know if you have more information to add to this section.
PhD Defenses
Francisco Queiroz | May 16, 2018
Thesis: "Physio-pathological role of ecto-5’-nucleotidase – a new target for neuroprotection"
Supervisors: Ângelo R. Tomé & Rodrigo A. Cunha
Get Involved
CNC Seminars
Spring Series - Next talks

@CNC, UC - Pólo I, Coimbra – 14h

• “Physical cues to guide vascular differentiation and assembly”
Sharon Gerecht (Johns Hopkins Institute for NanoBiotechnology, Baltimore, USA))
Host: Lino Ferreira
June 7

“Mammalian sperm motility: fertility, metabolism and selfish genes
Alexandra Amaral (Max Planck Institute for Molecular Genetics, Berlin, Germany)
Host: João Ramalho Santos
June 8

“Suppression of proteotoxicity by serotonergic signaling: impact on neurodegenerative diseases
Andreia Teixeira-Castro (ICVS, University of Minho)
Host: Ana Luísa Carvalho
June 15

“Neuroinflammation in Multiple Sclerosis: from target discovery to development of a therapeutic strategy”
Adelaide Fernandes (iMed.ULisboa, University of Lisbon)
Host: Ana Paula Silva
June 22

To be defined
Host: Luís. P. Almeida
June 29


@CNC / UC-Biotech, Cantanhede – 11h30

“Horizontal transfer of whole mitochondria restores tumorigenic potential in mtDNA-deficient cancer cells”
La-Fend Dong (School of Medical Science, Griffith University, Australia)
Host: Paulo Oliveira
June 8

“Oxidation of uric acid in inflammatory conditions: the underlying cause of uric acid-related pathologies”
Flávia Meotti (University of São Paulo, Brazil)
Host: Armindo Salvador
June 11

“What drives cytokinesis in bacterial cells?”
Mariana Gomes de Pinho (ITQB, NOVA University, Lisbon)
Host: Ana Eulálio
June 20

“Molecular Imaging with PET: from bench to bedside... and back”
Antero Abrunhosa (ICNAS, University of Coimbra)
Host: Lino Ferreira
June 27



Science Communication project financed by the Biochemical Society (UK)
The Science Communication Office would like to encourage the researchers to join us in this initiative. To participate send an email to

Science Communication monthly videos
If you are passionate about science and if you would like to share your work, we encourage you to participate in this project! Please fill out the registration form [here]
The Postdoctoral Representatives of CNC.IBILI present two Workshops on Career Development
Let us know if you have more informations or any suggestions, to improve "Synergies"


Science Communication Office | Ana Teresa Viegas, Sara Varela Amaral, Adalberto Fernandes, Claudia Cavadas (Coordinator)
Design and Layout:

Lia Lopes and Ana Sofia Mergulhão