CNC Internal Newsletter
Issue 17 | November 2018
 









Draft genome sequence of Bacillus amyloliquefaciens subsp. plantarum strain Fito_F321, an endophyte microorganism from Vitis vinifera with biocontrol potential.

Pinto C, et al, Stand Genomic Sci. 2018 Nov 1

Cysteine proteases secreted by the pinewood nematode, Bursaphelenchus xylophilus: In silico analysis.
Cardoso JMS, et al, Comput Biol Chem. 2018 Oct 26

Stress-induced host membrane remodeling protects from infection by non-motile bacterial pathogens.
Tawk C, et al, EMBO J. 2018 Nov 2

Process analytical technologies and injectable drug products: Is there a future?
Henriques J, et al, Int J Pharm. 2018 Oct 30

Miniature cheeses made with blends of chymosin and a vegetable rennet from flowers of Silybum marianum: Enzymatic characterization of the flower-coagulant peptidase.
Colombo ML, et al, Food Chem. 2018 Nov 15

Can antidiabetic drugs improve male reproductive (dys)function associated with diabetes?
Amaral S, et al, Curr Med Chem. 2018 Nov 1

Highlighting the Role of DC-NK Cell Interplay in Immunobiology and Immunotherapy.
Calmeiro J, et al, IntechOpen, 2018 Nov 5

 

Publications October | November

Region-specific control of microglia by adenosine A2A receptors: uncoupling anxiety and associated cognitive deficits in female rats.
Duarte JM, et al, Glia. 2018 Nov 21

Spectral features of nuclear DNA in human sperm assessed by Raman Microspectroscopy: Effects of UV-irradiation and hydration.
Da Costa R, et al, PLoS One. 2018 Nov 20

The antifungal activity of extracts of Osmundea pinnatifida, an edible seaweed, indicates its usage as a safe environmental fungicide or as a food additive preventing post-harvest fungal food contamination.
Silva P, et al, Food Funct. 2018 Nov 20

Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells.
Bajzikova M, et al, Cell Metab. 2018 Nov 9

Rethinking carbamazepine oral delivery using polymer-lipid hybrid nanoparticles.
Ana R, et al, Int J Pharm. 2018 Nov 12

Orientation of nitro-group governs the fluorescence lifetime of nitrobenzoxadiazole (NBD)-labeled lipids in lipid bilayers.
Filipe HAL, et al, Phys Chem Chem Phys. 2018 Nov 12.

Diminished O-GlcNAcylation in Alzheimer's disease is strongly correlated with mitochondrial anomalies.
Pinho TS, et al, Biochim Biophys Acta Mol Basis Dis. 2018 Nov 6.

Polymeric nanoengineered HBsAg DNA vaccine designed in combination with β-glucan.
Soares E, et al, Int J Biol Macromol. 2018 Nov 6

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Awards

Ana Ledo awarded the 2019 SFRR Europe Leopold Flohé Redox Pioneer Lecture at the Society for Free Radical Research – Europe Meeting to be held in Ferrara, Italy, that will be held on19-21 June 2019


 

 



 
 
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Scientific Meetings and Events


Paulo Oliveira gave a talk entitled "Role of Mitochondrial Metabolism in Aging" | November 21, 2018, University of Southern California - School of Gerontology (USA)






 
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Public Engagement in Science

Science and Technology week 2018 | 19 – 30 November, 2018 [see here]

Visits to Schools | 19 – 30 November, 2018 – Coimbra, Curia, Pombal, Lousã, Alvalade do Sado
13 visits to schools: more than 430 students from kindergarten to secondary schools
Participation of 27 researchers (CNC researchers: Adriana Marques, Ana Rita Álvaro, Ana Teresa Viegas, André Barbosa, Caroline Veloso, Catarina Seabra, Emanuel Candeias, Flávia Vicente, Henrique Faneca, Jéssica Costa, Joana Marques, João Cardoso, João Magalhães, Judite Coimbra, Luís Grilo, Mariana Laranjo, Patrícia Moreira, Ricardo Rodrigues, Rose Cordeiro, Sara Amaral and Tiffany Pinho)

Open Labs | 19 – 30 November, 2018
5 open labs: 78 students from kindergarten to secondary schools
Participation of 12 researchers (CNC researchers: Ana Duarte, Carla Lopes, Catarina Seabra, Débora Mena, Inês Alves, Jéssica Costa, Mariana Laranjo, Margarida Beatriz and Vera Martinho)

Brain Buskers – Scientists on the bus | 19 – 24 November, 2018 – Coimbra
More than 180 people reached
Participation of 11 CNC researchers (Ana Rita Álvaro, Bárbara Santos, Carina Henriques, Carla Lopes, João Cardoso, Laetitia Gaspar, Mariana Laranjo, Margarida Beatriz, Tiago Reis, Tiffany Pinho and Vera Martinho)

PubhD Coimbra 12th edition | 22 November, 2018 – Aqui Base Tango, Coimbra
Participation of Maria Inês Martins
Public: more than 50 persons on the audience

National Science day | 25 November, Vila Nova de Tazem
Participation of Catarina Seabra
Public: more than 90 persons reached

TV show “Sociedade Civil” (RTP2)
Episode “Investigadores” - Participation of João Ramalho-Santos | 19 November, 2018 [see here]
Episode “Neurociências” - Participation of Cláudia Cavadas | 22 November, 2018 [see here]

Total Numbers:
More than 820 persons reached during this initiative
40 researchers participated in this initiative

The Science and Technology Week was coordinated by CNC in collaboration with ICBR.
The Science Communication Office would like to acknowledge all the researchers who participated during this initiative, helping to promote and disseminate scientific culture and literacy.


Escola Ciência Viva | 19 – 30 November, 2018 [see here]
Science communication activities with students from 3rd cycle education – collaboration with Rómulo – Centro de Ciência Viva da Universidade de Coimbra

Hands-on activities:
Ana Teresa Viegas and Sara Amaral – 13 students reached
Ana Duarte, Carla Lopes, Débora Mena, Inês Alves, Margarida Beatriz and Vera Martinho – 23 students reached

Talks “Conversa com o Cientista”:
João Cardoso – 16 students reached | 23 November, 2018
Mariana Laranjo – 23 students reached | 30 November, 2018

Radio show “Medicina Nuclear” (RUC)
Participation of Catarina Seabra | 29 November, 2018

Science and technology week 2018
Science and technology week 2018
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CNC on the News

News about Sociedade Civil: ciência-investigadores:

RTP 2 - Sociedade Civil | November 19 (on TV)


News about Science and Technology week:

Diário As Beiras | November 20 (in press)
Diário As Beiras Online | November 20 [see here]
Campeão das Províncias Online | November 19 [see here]
Diario de Coimbra | November15 (in press)
Diário As Beiras | November 19 (in press)

News about mushroom that increases the complexity of new neurons formed in the adult hippocampus, an area of the brain linked to memory:

Boas Notícias Online | November 25 [see here]
i9 Magazine Online | November 25 [see here]
Gazela Rural | November 15 (in press)
Diário de Viseu | November 14 (in press)
Douro Hoje | November 14 (in press)
ALERT® Online | November 12 [see here]
Cabra Online (A) | November 9 [see here]
Diário As Beiras | November 9 (in press)
Diário As Beiras Online | November 9 [see here]
Diário de Coimbra | November 9 (in press)
Jornal Incentivo | November 9 (in press)
Viver Saudável Online | November 9 [see here]
TVI 24 Online | November 8 [see here]
TSF Online | November 8 [see here]
Sábado Online | November 8 [see here]
Saúde Online | November 8 [see here]
Sapo Online - Sapo Lifestyle Online | November 8 [see here]
Sapo Online - Sapo 24 Online | November 8 [see here]
PT Jornal Online | November 8 [see here]
Observador Online | November 8 [see here]
Notícias de Coimbra Online | November 8 [see here]
Notícias ao Minuto Online | November 8 [see here]
Impala Online | November 8 [see here]
Diário de Notícias Online | November 8 [see here]
Diário da Saúde Online | November 8 [see here]
Campeão das Províncias Online | November 8 [see here]
BeiraNews Online | November 8 [see here]
Atlas da Saúde Online | November 8 [see here]


News about PostDoc@UC at Exploratório

Diário de Coimbra | October 29 (in press)

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Opportunities
CNC Research Opportunities:

Marie Curie Early Stage Researcher
Biological sciences field [see here]
Application deadline: December 15, 2018

5 Master’s Research Fellowships:

Project PTDC/BIM-MED/0075/2014, “Mecanismos da indução hemogénica em fibroblastos humanos” [see here]
Application deadline: December 17, 2018

Project PTDC/QUI-OUT/32243/2017 “Membrane proteins – development of new computational approaches and its application to G-Protein Coupled Receptors”, [see here]
Application deadline: December 19, 2018

Project Infect-ERA/0001/2015 “Intracellular Staphylococcus aureus: deciphering bacterial and cellular factors involved in host cell invasion by clinically relevant strains to define new therapeutic approaches” (StaphIN) [see here]
Application deadline: December 24, 2018


Project IPOCI-01-0145-FEDER-031173 “Desenvolvimento de ferramenta moleculares para a doença de Machado-Joseph: moduladores de conformações tóxicas em proteínas com poliglutaminas” , [see here]
Application deadline: December 31, 2018


Project European Huntington Disease Network (EHDN) - Ref. 948/ACREGO [see here]
Application deadline: December 19, 2018


Fellowship for Investigation Technician

Project POCI-01-0145-FEDER-030550 “Imunoterapias contra sistemas de efluxo para modulação de bactérias multiresistentes” [see here]
Application deadline: December 24, 2018

PHD POSITIONS

1 PhD position
Biological sciences field [see here]
Application deadline: December 17, 2018

1 PhD position
Biological sciences field (biotechnology) [see here]
Application deadline: December 18, 2018

1 PhD position
Biological sciences field [see here]
Application deadline: January 10, 2019




















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Don't miss Out


16th Beer for Thought! Christmas Party Edition!

19 December 2018 | 17h30 @UC meal room (FMUC, 1st floor, POLO I)
Bring some food and share with us in the form: goo.gl/SLm9k1
Santa Claus is Coming! Bring your kids!
Don't forget your mug to taste the delicious homemade beer kindly provided by John Jones




11th annual Dance Your Ph.D. Contest!

1. Turn your Ph.D. thesis into a dance
2. Post the video on YouTube
Deadline: 14 January 2019
More informations here



Let us know if you have more information to add to this section.
PhD Defenses
 
Ana Sofia Morais | 16 November, 2018
Thesis: "The role of adenosine A2A receptor in the migration of cortical principal neurons”
Supervisors: Ricardo J. Rodrigues (Center for Neuroscience and Cell Biology) and Rodrigo A. Cunha (Faculty of Medicine, University of Coimbra & Center for Neuroscience and Cell Biology)

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Get Involved
CNC Seminars
Fall Series - Next talks

@CNC, Pólo I, Coimbra

"Optical approaches to study striatal dopamine neurotransmission and corticostriatal plasticity"
Daniela Pereira (Champalimaud Foundation, Lisbon)
Host: Paulo Pinheiro
December 7

"Cortical principal neurons migration entails adenosine A2A receptor activation"
Sofia Morais (CNC, University of Coimbra)
Host: Ricardo Rodrigues
December 14

"The imaging of neuroinflammation and oxidative stress in psychotic pathology"
Tiago Reis Marques (Institute of Clinical Sciences, Imperial College London, UK)
Host: Cláudia Pereira
December 21

 

@CNC / UC-Biotech, Cantanhede

• "Genetic regulation of susceptibility to infection in stem-cell transplantation"
Agostinho Carvalho (ICVS, University Minho)
Host: Hugo Fernandes
December 5

“Effects of lifelong training on T lymphocytes senescence”
Ana Teixeira (FCDEF, University of Coimbra)
Host: Hugo Fernandes
December 12

“The setting up of an SPF flock of chickens for research: establishing the world's first germ-free chicken flock producing germ-free eggs”
Leonard Moran (Ovagen Group Limited, Ireland)
&
“Large scale production of recombinant proteins using a poultry transgenic system”
Iain Shaw (Ovagen Group Limited, Ireland)
Host: Ricardo Pires
December 19

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Let us know if you have more informations or any suggestions, to improve "Synergies"
Credits

Contents:

Science Communication Office | Ana Teresa Viegas, Sara Varela Amaral, Adalberto Fernandes, Claudia Cavadas (Coordinator)
Design and Layout:

Lia Lopes and Ana Sofia Mergulhão