CNC Internal Newsletter
Issue 26 | August 2019
 
Publications July | August

Synaptogenesis Stimulates a Proteasome-Mediated Ribosome Reduction in Axons.
L, Jaffrey SR, et al, Cell Rep. 2019 Jul 23

The Administration of Chitosan-Tripolyphosphate-DNA Nanoparticles to Express Exogenous SREBP1a Enhances Conversion of Dietary Carbohydrates into Lipids in the Liver of Sparus aurata.
Silva-Marrero JI, et al, Biomolecules. 2019 Jul 24

FA-SAT ncRNA interacts with PKM2 protein: depletion of this complex induces a switch from cell proliferation to apoptosis.
Ferreira D, et all, Cell Mol Life Sci. 2019 Jul 25

Pre-analytical stability of novel cerebrospinal fluid biomarkers.
Willemse EAJ, et al, Clin Chim Acta. 2019 Oct; Epub 2019 Jul 23.

Nanostructuring lipid carriers using Ridolfia segetum (L.) Moris essential oil.
Miranda M, et al, Epub 2019 May 30

Biological Functions of Connexin43 Beyond Intercellular Communication.
Martins-Marques T, et al, Trends Cell Biol. 2019 Jul 26

The Kinetics of Small Extracellular Vesicle Delivery Impacts Skin Tissue Regeneration.
Henriques-Antunes H, et al, ACS Nano. 2019 Aug 27

Synaptic and memory dysfunction in a β-amyloid model of early Alzheimer's disease depends on increased formation of ATP-derived extracellular adenosine.
Gonçalves FQ, et al, Neurobiol Dis. 2019 Aug 5

Validation of an LC-MS/MS Method for the Quantification of Caffeine and Theobromine Using Non-Matched Matrix Calibration Curve.
Mendes VM, et al, Molecules. 2019 Aug 7

The dipeptidyl peptidase 4 inhibitor sitagliptin improves oxidative stress and ameliorates glomerular lesions in a rat model of type 1 diabetes.
Marques C, et al, Life Sci. 2019 Aug 6

The chemistry toolbox of multitarget-directed ligands for Alzheimer's disease.
Mesiti F, et al, Eur J Med Chem. 2019 Aug 1

SLMP53-2 Restores Wild-Type-Like Function to Mutant p53 through Hsp70: Promising Activity in Hepatocellular Carcinoma.
Gomes S, et al, Cancers (Basel). 2019 Aug 10

Language Predictors in Autism Spectrum Disorder: Insights from Neurodevelopmental Profile in a Longitudinal Perspective.
Mouga S, et al, J Abnorm Child Psychol. 2019 Aug 13

Shaping the Nrf2-ARE-related pathways in Alzheimer's and Parkinson's diseases.
Fão L, et al, Epub 2019 Aug 12. Review. PMID:31415806

Functional and Phenotypic Characterization of Tumor-Infiltrating Leukocyte Subsets and Their Contribution to the Pathogenesis of Hepatocellular Carcinoma and Cholangiocarcinoma.
Martín-Sierra C, et al, Transl Oncol. 2019 Aug 16

Antioxidant Versus Pro-Apoptotic Effects of Mushroom-Enriched Diets on Mitochondria in Liver Disease.
Fontes A, et al, Int J Mol Sci. 2019 Aug 16

SWATH Mass Spectrometry Applied to Cerebrospinal Fluid Differential Proteomics: Establishment of a Sample-Specific Method.
Anjo SI, et al, Methods Mol Biol. 2019

Untargeted Metabolomics Relative Quantification by SWATH Mass Spectrometry Applied to Cerebrospinal Fluid.
Mendes VM, et al, Methods Mol Biol. 2019

Targeted siRNA Delivery Using Lipid Nanoparticles.
Jorge A, et al, Methods Mol Biol. 2020

Use of recombinant proteins as a simple and robust normalization method for untargeted proteomics screening: exhaustive performance assessment.
Anjo SI, et al, Epub 2019 Jul 18.

Microglia cytoarchitecture in the brain of adenosine A2A receptor knockout mice: brain region and sex specificities.
Henriques CFS, et al, Eur J Neurosci. 2019 Aug 27

Poly(β-amino ester)-based gene delivery systems: From discovery to therapeutic applications.
Cordeiro RA, et al, J Control Release. 2019 Aug 24;

A Mitochondrial Approach to Cardiovascular Risk and Disease.
Veloso CD, et al, Curr Protein Pept Sci. 2019 Aug 30

Advances in biomarker detection: Alternative approaches for blood-based biomarker detection.
Rosado M, et al Adv Clin Chem. 2019

The Two Faces of Tumor-Associated Macrophages and Their Clinical Significance in Colorectal Cancer.
Pinto ML, et al, Front Immunol. 2019 Aug 20

Draft Genome Sequence of Brevundimonas sp. Strain T2.26MG-97, Isolated from a Rock Core Sample from 492.6 Meters Deep on the Subsurface of the Iberian Pyrite Belt.
Rodríguez-Robles E, et al, Microbiol Resour Announc. 2019 Aug 8

Synthesis and Antiproliferative Activity of Novel A-Ring Cleaved Glycyrrhetinic Acid Derivatives.
Alho DPS, et al, Molecules. 2019 Aug 14

A photodynamic antibacterial spray-coating based on the host-guest immobilization of the photosensitizer methylene blue.
Yao TT, et al, J Mater Chem B. 2019 Aug 21

Determining contributions of exogenous glucose and fructose to de novo fatty acid and glycerol synthesis in liver and adipose tissue.
Silva JCP, et al, etab Eng. 2019 Aug 29

The Brain Buskers Project: taking science to the streets
Barros-Viegas Ana Teresa , et all, The Biochemist, 2019 August

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Awards

EIT Health PhD Translational Fellowship Program

CNCResearcher and PhD student Fábio Rosa was awarded the judges' prize in the EIT Health PhD Translational Fellowship Program, in Oxford.
Fábio's project is focused on reprogramming skin cells (or fibroblasts) in immune cells for cancer therapy.

More on his research project [see here]







Fábio Rosa
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CNC on the News

News about “Why slim people have fatty liver?”
Público | August 28 (in press)
Público online | August 29 [see here]

News about “Scientific Occupation of young students in holidays time comes back to CNC”
Diário As Beiras | August 27 (in press)
Diário de Coimbra | August 27 (in press)

News about “ Doctoral Program student from CNC, wins European award”

Jornal de Notícias | August 23 (in press)
Jornal de Leiria | August 22 (in press)
Diário As Beiras | August 20 (in press)
Diário As Beiras Online | August 20 [see here]
Diário de Coimbra | August 20
Campeão das Províncias Online | August 19 [see here]
Notícias de Coimbra Online | August 19 [see here]

News about “It was deciphered the regulatory mechanism of the central nervous system”
Incentivo | August 16 (in press)
Jornal de Leiria | August 15 (in press)
Diário de Viseu | August 14 (in press)
Alert Online | August 13 [see here]
Mundo Português Online | August 11 [see here]
Diário de Coimbra | August 10 (in press)
Correio da Manhã | August 9 (in press)
Diário As Beiras | August 9 (in press)
S+ Online | August 8 [see here]
Saúde Online | August 8 [see here]
AEIOU.pt Online - ZAP AEIOU Online | August 8 [see here]
Campeão das Províncias Online | August 8 [see here]
Diário As Beiras Online | August 8 [see here]
Estrategizando Online | August 8 [see here]

Estrategizando Online | August 8 [see here]
Impala Online | August 8 [see here]
Informa+ Online | August 8 [see here]
JM Online | August 8 [see here]
Jornal Médico.pt Online | August 8 [see here]
Lusa Online | August 8 [see here]
Notícias ao Minuto Online | August 8 [see here]
Notícias de Coimbra Online | August 8 [see here]
Notícias de Coimbra Online | August 8 [see here]
Observador Online | August 8 [see here]
PT Jornal Online | August 8 [see here]
Público Online | August 8 [see here]
Sapo Online - Sapo 24 Online | August 8 [see here]
Sapo Online - Sapo Lifestyle Online | August 8 [see here]

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Opportunities

CNC Research Opportunities:

Master-holder Fellowship @ CNC
Job/Fellowship Reference: BIM POCI-01-0145-FEDER-029002
Main research field: Neurosciences
Deadline: October 7, 2019
More information: www.eracareers.pt/opportunities/index.aspx?task=global&jobId=117386





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Science Communication Office | Ana Teresa Viegas, João Cardoso, Lia Lopes, Sandra Pereira and Sara Varela Amaral
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