CNC Internal Newsletter
Issue 19 | January 2019
 
Publications December | January

c-Src regulates Nrf2 activity through PKC? after oxidant stimulus.
Fão L, et al, Biochim Biophys Acta Mol Cell Res. 2019 Jan 24

Caffeine and cannabinoid receptors modulate impulsive behavior in an animal model of Attentional Deficit and Hyperactivity Disorder.
Leffa DT, et al, Eur J Neurosci. 2019 Jan 22.

Quercetin dual interaction at the membrane level.
de Granada-Flor A, et al, Chem Commun (Camb). 2019 Jan 21

The Role of Beclin-1 Acetylation on Autophagic Flux in Alzheimer's Disease.
Esteves AR, et al, Mol Neurobiol. 2019 Jan 19.

Unveiling the molecular crosstalk in a Human Induced Pluripotent Stem Cell Derived Cardiac Model.
Abecasis B, et al, Biotechnol Bioeng. 2019 Jan 19.

Biosynthesis of mycobacterial methylmannose polysaccharides requires a unique 1-O-methyltransferase specific for 3-O-methylated mannosides.
Ripoll-Rozada J, et al, Proc Natl Acad Sci U S A. 2019 Jan 15

The Retina as a Window or Mirror of the Brain Changes Detected in Alzheimer's Disease: Critical Aspects to Unravel.
Chiquita S, et al, Mol Neurobiol. 2019 Jan 5

Nose-to-brain delivery of lipid-based nanosystems for epileptic seizures and anxiety crisis.
Costa C, et al, J Control Release. 2019 Jan 2

Suicide Gene Therapy for Oral Squamous Cell Carcinoma.
Faneca H, et al, Methods Mol Biol. 2019

Region-specific control of microglia by adenosine A2A receptors: uncoupling anxiety and associated cognitive deficits in female rats.
Duarte JM, et al, Glia. 2019 Jan

Rethinking carbamazepine oral delivery using polymer-lipid hybrid nanoparticles.
Ana R, et al, Int J Pharm. 2019 Jan 10

Preparation of gentamicin sulfate eluting fiber mats by emulsion and by suspension electrospinning.
Coimbra P, et al, Mater Sci Eng C Mater Biol Appl. 2019 Jan 1

Process analytical technologies and injectable drug products: Is there a future?
Henriques J, et al, Int J Pharm. 2019 Jan 10

Impact of Caffeine Consumption on Type 2 Diabetes-Induced Spatial Memory Impairment and Neurochemical Alterations in the Hippocampus
Duarte JMN, et al, Front Neurosci. 2019 Jan 9

Early Cardiac Mitochondrial Molecular and Functional Responses to Acute Anthracycline Treatment in Wistar Rats
Pereira GC, et al, Toxicol Sci. 2019 Jan 24

Association between Adipokines and Biomarkers of Alzheimer's Disease: A Cross-Sectional Study
Letra L, et al, J Alzheimers Dis. 2019

Shedding light on microRNA function via microscopy-based screening
.
Rodrigues Lopes I, et al, Methods. 2019 Jan 1

Cordycepin activates autophagy through AMPK phosphorylation to reduce abnormalities in Machado-Joseph disease models.
Marcelo A, et al, Hum Mol Genet. 2019 Jan 1

Machado-Joseph disease/spinocerebellar ataxia type 3: lessons from disease pathogenesis and clues into therapy.
Matos CA, et al, J Neurochem. 2019 Jan

Toxicity of lupane derivatives on anionic membrane models, isolated rat mitochondria and selected human cell lines: Role of terminal alkyl chains.
Carvalho FS, et al, Chem Biol Interact. 2018 Dec 25

Neuronal Adenosine A2A Receptors Are Critical Mediators of Neurodegeneration Triggered by Convulsions.
Canas PM, et al eNeuro. 2018 Dec 26.

Adenosine A2A Receptors in the Rat Prelimbic Medial Prefrontal Cortex Control Delay-Based Cost-Benefit Decision Making.
Leffa DT, et al, Front Mol Neurosci. 2018 Dec 20

Multimodal highly fluorescent-magnetic nanoplatform to target transferrin receptors in cancer cells.
Cabral Filho PE, et al, Biochim Biophys Acta Gen Subj. 2018 Dec

Mechanistic study of the adjuvant effect of chitosan-aluminum nanoparticles.
Lebre F,et al, Int J Pharm. 2018 Dec 1

Donepezil structure-based hybrids as potential multifunctional anti-Alzheimer's drug candidates.
Piemontese L, et al, J Enzyme Inhib Med Chem. 2018 Dec

Loss of hierarchical imprinting regulation at the Prader-Willi/Angelman syndrome locus in human iPSCs.
Pólvora-Brandão D, et al, Hum Mol Genet. 2018 Dec 1

A translational view of cells' secretome analysis - from untargeted proteomics to potential circulating biomarkers.
Anjo SI, et al, Biochimie. 2018 Dec

cIAP1 regulates the EGFR/Snai2 axis in triple-negative breast cancer cells.
Majorini MT, et al, Cell Death Differ. 2018 Dec

Cooperative Transcription Factor Induction Mediates Hemogenic Reprogramming
Gomes AM., et al, Cell Reports 2018 Dec 4

Let us know if you have more information to add to this section.
 
Events & Meetings

1st Microbiome-Gut-Brain Axis Joint Meeting
December 7, 2018 @ Coimbra









Nanogateway Winter School
January 16-18, 2019 @ Braga

Participation of:
- Paulo Oliveira: "Mitochondria as a Pharmacological and Toxicological Target in Drug Development"

- Lino Ferreira: "Triggerable meterials for regenerative medicine"

1st Microbiome-Gut-Brain Axis Joint Meeting
Nanogateway Winter School
Let us know if you have more information to add to this section.
 
Public Engagement in Science
Workshop "Dar Corpo ao Cérebro" | January 26, 2019 @ Convento S. Francisco, Coimbra
Science & art workshop in collaboration with Marionet and following the theatre play "Glândula Secreta".
Participation of Ana Teresa Viegas, Bárbara Santos and Laetitia Gaspar | 20 children and families reached



Escola Ciência Viva
| January, 2019
Science communication activities with students from 3rd cycle education – collaboration with Rómulo – Centro de Ciência Viva da Universidade de Coimbra:

• 7 January | Participation of Ana Teresa Viegas, João Cardoso and Luísa Cortes | 27 children reached

• 14 January | Participation of Catarina Seabra, Jéssica Costa and Mariana Laranjo [see here] | 25 children reached

• 21 January | Participation of Caroline Veloso, Inês Simões, Mireia Alemany Pàges, Paulo Oliveira and Vilma Sardão [see here] | 20 children reached

• 28 January | Participation of Ana Rita Álvaro, Bárbara Santos, Catarina Pacheco, Laetitia Gaspar, Marisa Ferreira and Rafael Daganha | 23 children reached



Escola Ciência Viva 2019
Launch of the CNC Calendar 2019:
If you wish to purchase your calendar, ask for it at the Science Communication Office, or at the Secretariat of the Board of Directors (pólo I - 1st floor)
2019 CNC Calendar Cover
Let us know if you have more information to add to this section.
 
CNC on the News

News about  João Nuno Moreira Presentation on the 1st Portuguese symposium on Urology Investigation and Innovation:

Jornal Médico.pt Online  | December 28 [see here]
Jornal Medico | December 31 (in Press)

News about Integration on B2B:

Diário de Coimbra |  January 20 (in Press)

News about new targets for fighting bacteria that cause lung infections:

TSF Online | January 23 [see here]
Sapo Online - Sapo 24 Online | January 23 [see here]
Notícias Saúde Online | January 23 [see here]
Notícias de Coimbra Online | January 23 [see here]
Notícias ao Minuto Online | January 23  [see here]
Mundo Português Online | January 23  [see here]
Jornal Médico.pt Online | January 23 [see here]
Diário de Notícias Online | January 23 [see here]
Diário da Saúde Online | January 23 [see here]
Atlas da Saúde Online | January 23 [see here]
Índice.eu Online | January 24 [see here]
Sapo Online - Sapo Lifestyle Online | January 24 [see here]
Diário de Coimbra | January 24 (in Press)
Diário As Beiras January 24 (in Press)
Campeão das Províncias Online January 24 [see here]
News Farma Online - My Pneumologia Online | January 25 [see here]
O Despertar | January 31 [see here]

News about Protocol with APELA:

Campeão das Províncias Online | January 28 [see here]
Diário de Coimbra | January 29 (in Press)
Diario As Beiras | January 30 (in Press)
Diário de Coimbra online | January 31 [see here]

Let us know if you have more information to add to this section.
 
Opportunities

CNC Research Opportunities:


Master Positions
:
1 Master Fellowship
Project BIM: "Distúrbios afetivos: biomarcadores e deteção precoce” [see here]
Application deadline: February 8, 2019

1 Master Fellowship
Project BIM: BIOINFORMATICIAN Metafluidics [see here]
Application deadline : February 6, 2019

1 Master Fellowship
Project BIM: MICROBIOLOGY Metafluidics [see here]
Application deadline: February 6, 2019




PhD Positions:


1 PhD position | Reference: INV JR 2018 Nº 38. 029414
Biological sciences field [see here]
Application deadline:February 25, 2019

1 PhD position | Reference :INV JR 2019 Nº 40. 029002
Biological sciences field [see here]
Application deadline:February 26, 2019


1 PhD position | Reference: INV JR 2019.39 N º 0288599
Biological sciences field [see here]
Application deadline:February 26, 2019


1 PhD position | Reference: INV JR 2019.41-Nº 030712
Biological sciences field [see here]
Application deadline: March 1, 2019


1 PhD position | Reference: INV JR 2019.43- n. º 030943
Biological sciences field [see here]
Application deadline: March 8, 2019


1 PhD position | Reference: INV JR 2019.42 Nº 030737
Biological sciences field [see here]
Application deadline: March 4, 2019








Let us know if you have more information to add to this section.

 
PhD Defenses
Sofia Ferreira | 29 January, 2019
Thesis: "The role of P2 receptors in the migration of medial ganglionic eminence-derived interneurons”
Supervisors: Ricardo J. Rodrigues (Center for Neuroscience and Cell Biology) and Rodrigo A. Cunha (Faculty of Medicine, University of Coimbra & Center for Neuroscience and Cell Biology)
Let us know if you have more information to add to this section.
 
New faces | New Roles
João Cardoso
Science Communication Office
Public Information Officer
 
Don't miss Out

FameLab 2019 International Science Communication Competition [see here]
Application deadline: February 9, 2019
Regional Final at Rómulo Centro Ciência Viva, University of Coimbra: February 20 (2.30pm)

Brain Awareness Week 2019 is coming!
If you want to be involved in this science communication experience, please fill in the form

If you know any group of people (schools, associations, or other) that wish to enroll in our activities, please share this form






Let us know
if you have more information to add to this section.

BAW 2019
 
Get Involved
CNC Seminars
Winter Series - Next talks

@CNC, Pólo I, Coimbra


"Deregulation of BDNF signalling in Alzheimer´s Disease: new opportunities for treatment "
Maria José Diógenes (IMM, University of Lisbon)
Host: Ana Cristina Rego
February 15, 14h00


"Jornalistas e cientistas: como comunicar? "
Teresa Firmino ( Jornal Público)
Host: Sara Amaral
February 19, 14h00


"Science Communication in Portugal - how far are we? "
Joana Lobo Antunes (ITQB-UNL and Rede SciComPT)
Host: Sara Amaral
February 22, 11h00


"Fine Timescale Coordination of Thalamic Activity with mPFC and CA1 non-REM Oscilations"
Carmen Varela (Psychology Department Florida Atlantic University)
Host: Ana Luisa Carvalho
February 22, 14h00

@CNC / UC-Biotech, Cantanhede


"Rational Protein Engineering"
Alexandra Carvalho (CNC, UC-Biotech)
Host: Lino Ferreira
February 6 , 11h30

"Blockchain. What is it? Good for?"
Paulo Rupino (CISUC, Department of Informatics Engineering, University of Coimbra)
Host: Ricardo Pires
February 20 , 14h00

 
PDBEB Advanced Courses 2018/2019 [see here]

PDBEB Courses 2018/2019 - Connecting the Researchers with the society
Registration here
February 18 - 22, 2019

PDBEB Courses 2018/2019 - Computational Biology
February 25 - March 1, 2019

PDBEB Courses 2018/2019 - Metabolism
March 11 - 15, 2019

PDBEB Courses 2018/2019 - Fighting Infection
March 18 - 22, 2019

PDBEB Courses 2018/2019 - Synapse structure and function
March 25 - 29, 2019

PDBEB Courses 2018/2019 - Neuronal circuits & behavior
April 1 - 5, 2019

PDBEB Courses 2018/2019 - Advanced Therapies
April 22 - 26, 2019

PDBEB Courses 2018/2019 - Proteomics Approaches in Life Sciences
May 6 - 10, 2019

PDBEB Courses 2018/2019 - Drug development
May 13 - 24, 2019

 
 
 
Let us know if you have more informations or any suggestions, to improve "Synergies"
Credits:

Science Communication Office | Ana Teresa Viegas, João Cardoso, Lia Lopes, Sara Varela Amaral