CNC Internal Newsletter
Issue 21 | March 2019
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Publications February | March

Abnormal mGluR-mediated synaptic plasticity and autism-like behaviours in Gprasp2 mutant mice.
Edfawy M et al, Nat Commun. 2019 Mar 29

Alterations in GABAA-Receptor Trafficking and Synaptic Dysfunction in Brain Disorders.

Mele M, et al, Front Cell Neurosci. 2019 Mar 7

Studies of antimicrobial resistance in rare mycobacteria from a nosocomial environment.
Pereira SG, et al, BMC Microbiol. 2019 Mar 19

A Pathogen and a Non-pathogen Spotted Fever Group Rickettsia Trigger Differential Proteome Signatures in Macrophages.
Curto P, et al, Front Cell Infect Microbiol. 2019 Mar 6

Studies of antimicrobial resistance in rare mycobacteria from a nosocomial environment.
Pereira SG, et al, BMC Microbiol. 2019 Mar 19

Hippocampal mossy fibers synapses in CA3 pyramidal cells are altered at an early stage in a mouse model of Alzheimer's disease.
Viana da Silva S, et al, J Neurosci. 2019 Mar 18

Synthesis and process optimization of symmetric and unsymmetric barbiturates C5-coupled with 2,1-benzisoxazoles.
Serrano JL, et al, Mol Divers. 2019 Mar 14

Functional characterization of iPSC-derived arterial- and venous-like endothelial cells.
Rosa S, et al, Sci Rep. 2019 Mar 7

Disrupted AMPA Receptor Function upon Genetic- or Antibody-Mediated Loss of Autism-Associated CASPR2.
Fernandes D, et al, Cereb Cortex. 2019 Mar 4.

A longitudinal multimodal in vivo molecular imaging study of the 3xTg-AD mouse model shows progressive early hippocampal and taurine loss.
Chiquita S, et al, Hum Mol Genet. 2019 Feb 28

MicroRNA-186-5p controls GluA2 surface expression and synaptic scaling in hippocampal neurons.
Silva MM, et al, Proc Natl Acad Sci U S A. 2019 Mar 19

Chronic adenosine A2A receptor blockade induces locomotor sensitization and potentiates striatal LTD IN GPR37-deficient mice.
Morató X, et al, J Neurochem. 2019 Mar

MicroRNAs at the Host-Bacteria Interface: Host Defense or Bacterial Offense.
Aguilar C, et al, Trends Microbiol. 2019 Mar



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Events & Meetings


III Meet.lab
| March 16, organized by Núcleo de Estudantes de Biologia da AAC

Speakers:
João Nuno Moreira: | Biomarkers and Drug Targeting
Paulo Oliveira | From the Mitochondria to Business: The example of MitoTag

Workshops:
João Cardoso |
Talking science with your Granny
Ana Luísa Carvalho & Gladys Caldeira | Cognitive Improvement: Truth or Myth
Teresa Oliveira | Introduction to Automatic Learning: Practical Session
Sara Rebelo | Male Gamete: What do we know just by looking at it?



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Events @ CNC
17th Beer for Thought | March 28, 2019 CNC Library, Pólo I
17th Beer for Thought
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Public Engagement in Science
Brain Awareness Week 2019 (BAW2019):

• “Brain O’Clock – time to make it right!” | March 1 – 30, 2019 [see here]

• Lab Time – Open Labs at CNC and iCBR | March 1 – 30, 2019

• School Time – Researchers’ visits to kindergartens, elementary, middle and high schools, associations, seniors’ centers and universities | March 1 – 30, 2019

• Travel Time – Researchers’ took science to the city’s buses | March 18 – 22, 2019

• Debate time – “Quando o cérebro fica dependente” – Public event | March 17, 2019 Fnac – Fórum Coimbra 
Moderated by Cristina Rego 

• Radio time – Scientists on the radio “Ciência aos Domingos” at RUC
Nuno Empadinhas [see here]
Sandra Morais Cardoso [see here]

• Selfie Time – “Selfie Science” videos
Ana Duarte [see here]
Filomena Silva [see here]
Ana Luísa Cardoso [see here]
Anna Pliássova [see here]

• Movie Time – “Inside Out” movie at the 17th Beer for Thought | March 28, 2019, CNC Library, Pólo I

• Game Time – “Braindemic” game at the Games’ night | March 28, 2019, Casa das Artes

• Pub Time - 16th PubhD Coimbra | March 28, 2019, Aqui Base Tango, Coimbra, Portugal
Participation of Francisco Queiroz and Mariline Silva

• Sleep Time – World Sleep Day | March 15, 2019
Awareness video [see here]
“Dormir bem, envelhecer melhor” – Public event | Auditório do Conservatório de Música de Coimbra



Pub Time - 16th PubhD Coimbra
The Brain Awareness Week was coordinated by CNC in collaboration with ICBR.
The Science Communication Office would like to acknowledge all the researchers who participated during this initiative, helping to promote and disseminate scientific culture and literacy.
Let us know how was your BAW experience by filling in this questionnaire [see here]

Launch of the monthly videos “ASK (Always Seeking Knowledge) Researchers”
Catarina Seabra [see here]

Escola Ciência Viva | 19 March, Rómulo – Centro de Ciência Viva da Universidade de Coimbra
Participation of Inês Albino and Francesca Tomatis

UniStem Day | 13-15 March, CNC
Participation of the Molecular Therapy of Brain Disorders group

World Tuberculosis Day | 24 March
Publication of the comic strip “Viagens na Tuberculose” at Público [see here]
Participation of the Molecular Mycobacteriology and Microbiome group

UniStem Day World Sleep Day
Escola Ciência Viva
Let us know if you have more information to add to this section.
CNC on the News

News about World Sleep Day:
Vital Health Online | March 4 [see here]
Tempo Medicina Online | March 4 [see here]
Atlas da Saúde Online | March 3 [see here]
Índice.eu Online | March 4 [see here]
Coolectiva Online | March 7 [see here]
News Farma Online - My Pneumologia Online | March 8 [see here]
Notícias de Coimbra Online | March 9 [see here]
Raio X Online | March 11 [see here]
Diário da Saúde Online | March 11 [see here]
Diário de Coimbra | March 12 (in Press)
Diário As Beiras | March 12 (in Press)
Atlas da Saúde Online | March 12 [see here]
AEIOU.pt Online - ZAP AEIOU Online | March 14 [see here]
Índice.eu Online | March 15 [see here]
Minho Digital Online | March 15 [see here]
Expresso Online | March 15 [see here]
Envelhecer Online | March 15 [see here]
Raio X Online | March 22 [see here]

News about the involvement of molecule in the regulation of brain balance:
Público Online | March 6 [see here]
Público Online | March 6 (in press)

News about Brain Awareness Week:
Notícias de Coimbra Online | March 11 [see here]
Diário de Coimbra | March 12 (in press)
Cabra Online (A) | March 13 [see here]

News about protocol between CNC and CMC
Campeão das Províncias Online | March 14 [see here]

News About Convenção do Ensino Superior
Público Online | March 15 [see here]
Diário de Coimbra | March 15 (in press)

News about discovery about method that facilitate the diagnosis of neurodegenerative disorders:
TVI 24 Online | March 20 [see here]
TSF Online | March 20 [see here]
Saúde Online | March 20 [see here]
Sapo Online - Sapo Lifestyle Online | March 20 [see here]
Sapo Online - Sapo 24 Online | March 20 [see here]
Notícias de Coimbra Online | March 20 [see here]
Notícias ao Minuto Online | March 20 [see here]
Jornal Médico.pt Online | March 20 [see here]
Diário de Notícias Online | March 20 [see here]
Diário da Saúde Online | March 20 [see here]
Diário As Beiras Online | March 20 [see here]
Campeão das Províncias Online | March 20 [see here]
Tech em Português Online | March 21 [see here]
Diário de Coimbra | March 21 (in Press)
Diário As Beiras | March 21 (in Press)
ALERT® Online | March 22 | [see here]
Índice.eu Online | March 25 [see here]
Incentivo (PT) | March 25 (in Press)

News about seminar at CNC about Cibersecurity:
Notícias de Coimbra Online | March 20 [see here]
Notícias de Coimbra Online | March 22 [see here]
Jogo Online (O) March 22 [see here]
Diário de Notícias Online | March 22 [see here]
Diário As Beiras | March 22 & March 23 (in press)
TSF Online | March 22 [see here]

News about Tuberculosis world day:
Público Online | March 24 [see here]
Publico | March 24 (in Press)

Interview with President of CNC:
Diário de Coimbra Online | March 25 [see here]
Diário de Coimbra | March 25 (in Press)

Interview with Carlos Filipe Pereira:
Program "Saúde em Dia" (Season 3, episode 4), Channel NOS Saúde+ [see here]

Let us know if you have more information to add to this section.
Opportunities

CNC Research Opportunities:

14 Early Stage Researcher positions @ Syn2psy
Research Field: MSc degree in Biochemistry, Biology, Biological chemistry, Biomedical sciences, Pharmacy, Bio-informatics
Deadline: May 15, 2019
More Information: www.syn2psy.eu/

1 PhD position | Reference: INV JR 2019.47 N º 28160
Biological sciences field [see here]
Application deadline: May 2, 2019

1 PhD position | Reference: INV JR 2019.46 nº 028607
Biological sciences field [see here]
Application deadline: May 2, 2019

1 PhD position | Reference: INV JR 2019.48 n. º 029716
Health and Medical Sciences field [see here]
Application deadline: May 8, 2019





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Don't miss Out

Below you can find the text and the publicizing rules to the eligibility of the research projects. You should use this text in all the materials that you publish under your project and CNC umbrella. 

The affiliation that all the CNC researchers should use is CNC - Center for Neuroscience and Cell Biology

EN: «This work was financed by the European Regional Development Fund (ERDF), through the Centro 2020 Regional Operational Programme under project CENTRO-##-####-FEDER-###### (insert acronym)* and through the COMPETE 2020 - Operational Programme for Competitiveness and Internationalisation and Portuguese national funds via FCT – Fundação para a Ciência e a Tecnologia, under project[s] POCI-##-####-FEDER-######* and UID/NEU/04539/2019

The reference UID/NEU/04539/2019 is mandatory (Strategic Plan CNC.IBILI).  

*references of your funding project(s)

All the rules are available at:

CENTRO 2020: http://www.centro.portugal2020.pt/index.php/regras-de-comunicacao
COMPETE 2020: http://www.poci-compete2020.pt/sobre-nos/comunicacaoFCT: https://www.fct.pt/apoios/projectos/regulamentos.phtml.pt 
        https://www.fct.pt/logotipos/index.phtml.pt

Regarding the BID and individual fellowships (directly funded by FCT) the rules are available at: 
https://www.fct.pt/apoios/bolsas/docs/RegulamentoBolsasFCT2018.pdf, article 35º.

.................

PT: «[...] co-financiado por Fundos FEDER, através do Programa Operacional Regional Centro 2020 no âmbito do projecto CENTRO-##-####-FEDER-###### (inserir acrónimo)*, e através do Programa Operacional Competitividade e Internacionalização COMPETE 2020 e de fundos nacionais via FCT – Fundação para a Ciência e a Tecnologia, no âmbito do(s) projecto(s) POCI-##-####-FEDER-######  (inserir acrónimo(s))* e UID/NEU/04539/2019.»;

A referência UID/NEU/04539/2019 é obrigatória (Plano Estratégico CNC.IBILI)

*referências dos projetos que vos financiam 

As normas de Informação e Publicitação de Apoios para Beneficiários estão disponíveis em: 

CENTRO 2020: http://www.centro.portugal2020.pt/index.php/regras-de-comunicacao
COMPETE 2020: http://www.poci-compete2020.pt/sobre-nos/comunicacao
FCT: https://www.fct.pt/apoios/projectos/regulamentos.phtml.pt 
        https://www.fct.pt/logotipos/index.phtml.pt

Quanto às bolsas BID ou BD individuais (directamente atribuídas pela FCT), ver: 
https://www.fct.pt/apoios/bolsas/docs/RegulamentoBolsasFCT2018.pdf, artigo 35º


Let us know if you have more information to add to this section.

Get Involved
CNC Seminars
Spring Series - Next talks

@CNC, Pólo I, Coimbra


"The role of the hippocampal CA2 area in social memory (dys)function"
Torcato Meira (ICVS, School of Medicine, University of Minho, Portugal & Department of Neuroscience, Zuckerman and Kavli Institutes, Vagelos College of Physicians and Surgeons, Columbia University, New York, USA)
Host: Ângela Inácio
May 3, 14h00


"Design and optimization of potent, CNS-penetrant transthyretin stabilizers with a little help from Machine Learning"
Carlos Simões (Chief Technology Officer, BSIM Therapeutics)
Host: João Nuno Moreira
May 17, 14h00


"Micronutrient Sensing and Intestinal Immune Defence"
Manuela Ferreira (CNC, UC-Biotech & Champalimaud Foundation)
Host: Paulo Oliveira
May 31, 14:00

"Neuronal KCNQ channelopathies: a paradigm for rare developmental disorders highlighting therapeutic targets for more common diseases"
Maurizio Taglialatela (Department of Neuroscience, University of Naples Federico II, Naples, Italy)
Host: Ana Luísa Carvalho
June 21, 14:00


@CNC / UC-Biotech, Cantanhede


"The peculiarities of prostate cancer metabolism"
Silvia Socorro (CICS-UBI-Health Sciences Research Centre, Faculty of Health Sciences, University of Beira Interior)
Host: Paulo Oliveira
April 17, 11h30


"Evolution and functional relevance of protein phosphorylation"
Pedro Beltrao (European Bioinformatics Institute EMBL-EBI)
Host: Bruno Manadas
May 19, 11:30

"Protease networks in skin inflammation and repair"
Ulrich auf dem Keller (European Bioinformatics Institute EMBL-EBI)
Host: Isaura Simões
May 10, 11:30




PDBEB Advanced Courses 2018/2019 [see here]

Registration by email to srocha@cnc.uc.pt


PDBEB Courses 2018/2019 - Advanced Therapies
April 22 - 26, 2019

PDBEB Courses 2018/2019 - Synapse structure and function
April 29 - May 3, 2019

PDBEB Courses 2018/2019 - Proteomics Approaches in Life Sciences
May 6 - 10, 2019

PDBEB Courses 2018/2019
- Drug development
May 13 - 24, 2019

Registration [here
till May 3, 2019
Registration [here]
Registration of high school students [here] Abstract submission:
April 15, 2019 [see here]


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Let us know if you have more informations or any suggestions, to improve "Synergies"
Credits

Science Communication Office | Ana Teresa Viegas, João Cardoso, Lia Lopes, Sara Varela Amaral