2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007
Publications 2013
Barosa C, Jones JG, Rizza R and Basu R. (2013) Acetaminophen glucuronide and plasma glucose report identical estimates of gluconeogenesis and glycogenolysis for healthy and pre-diabetic subjects using the deuterated water method. Magn. Res. Med. 70:315-319. IF: 3.27, Q1

Basu R, Barosa C Norby B, Dicke B, Jones JG, Basu A & Rizza RA. (2013) Pathogenesis of prediabetes: Role of the liver in isolated fasting hyperglycemia and combined fasting and postprandial hyperglycemia. J. Clin. Endo. & Metab. 98, E409-E417. IF: 6.43, Q1

Carvalho F, Duarte J, Simoes A, Cruz P and Jones JG. (2013) Noninvasive measurement of murine hepatic acetyl-CoA 13C-enrichment following overnight feeding with 13C-enriched fructose and glucose. BioMed Research International (formerly  Journal of Biomedicine and Biotechnology. Article Number: 638085 DOI: 10.1155/2013/638085. IF: 2.88, Q2

Cerofolini L, Fields G, Fragai M, Geraldes CFGC, Luchinat C, Parigi G, Ravera E, Svergun DI, Teixeira JMC. (2013) Examination of matrix metalloproteinase-1 (MMP-1) in solution: a preference for the pre-collagenolysis state. (2013) J. Biol.Chem., 288, 30659-30671. IF: 5.023, Q1

de Sá A, Bonnet CS, Geraldes CFGC, Tóth É, Ferreira PMT, André JP. (2013)     Thermodynamic stability and relaxation studies of small, triaza-macrocylic Mn(II) chelates. Dalton Trans., 42, 4522-4532. IF: 3.806, Q1

Delgado TC, Martins FO, Carvalho F, Gonçalves A, Scott,DK, O’Doherty RM, Macedo MP and Jones JG. (2013) 2H-enrichment distribution of hepatic glycogen from 2H2O reveals the contribution of dietary fructose to glycogen synthesis.  Am. J. Physiol. 304, 384-391. IF: 4.51, Q1

Ferreira MF, Martins AF, Martins C, Tóth E, Rodrigues TB, Calle D, Cerdan S, López-Larrubia P, Martins JA, Geraldes CFGC. (2013) Amide conjugates of the DO3A-N-(a-amino)propionate ligand: leads for stable, high relaxivity Contrast Agents for MRI? Contrast Media Mol. Imaging, 8, 40-49. IF: 3.221, Q2

Fonseca CP, Montezinho LP, Castro MMC, Fonseca LL, Alves PM, Santos H, Geraldes CFGC. (2013) 23Na Multiple Quantum Filtered NMR Characterization of Na+ Binding and Dynamics in Animal Cells – a Comparative Study and Effect of Na+/Li+ Competition. Eur. Biophys. J., 42, 503-519. IF: 2.274,  Q3

Gonçalves C, Lalatonne Y, Melro L, Badino G, Ferreira MFM, David L, Geraldes CFGC, Motte L, MJA, GFM. (2013) New dextrin nanomagnetogels as contrast agents for Magnetic Resonance Imaging. J. Mater. Chem. B, 1, 5853-5864. IF: 6.108, Q1

Leitão HS, Doblas S, d’Assignies G, Garteiser P, Daire Jean-L, Paradis V, Geraldes CFGC, Vilgrain V, Beers BEV. (2013) Fat deposition decreases diffusion parameters at MRI: a study in phantoms and patients with liver steatosis. European Radiology, 23, 461-467. IF: 3.548, Q1

Leitão HS, Paulino C, Rodrigues D, Gonçalves SI, Marques Cr, Carvalheiro M, Geraldes CFGC & Caseiro-Alves F. (2013) MR fat fraction mapping: a simple biomarker for liver steatosis quantification in nonalcoholic fatty liver disease patients. Acad. Radiol., 20, 957-961. IF: 3.221, Q2

Martins AF, Morfin J-F, Kubíčková A, Kubíček V, Buron F, Suzenet F,  Salerno M, Lazar AN, Duyckaerts C, Arlicot N, Guilloteau D, Geraldes CFGC, Tóth É. (2013) PiB-conjugated, metal-based imaging probes: multimodal approaches for the diagnostics of b-amyloid plaques. ACS Med. Chem. Lett., 4, 436-440. IF: 3.311, Q2

Martins AF, Prata MIM, Rodrigues SPJ, Geraldes CFGC, Riss PJ, Coarasa AA, Burchardt C, Kroll C, Roesch Frank. (2013)     Spectroscopic, radiochemical, and theoretical studies of the Ga3+-N-2-hydroxyethyl piperazine-N’-2-ethanesulfonic acid (HEPES buffer) system: Evidence for the formation of Ga3+- HEPES complexes in 68Ga labeling reactions. Contrast Media Mol. Imaging, 8, 265-273. IF: 3.221, Q2

Martins FO, Rito J, Jarak I, ViegasI, Pardal MA, Macedo MP and Jones JG. (2013) Disposition of [U-2H7]glucose into hepatic glycogen in rat and in seabass. Comp. Biochem & Physiol. A. 166: 316-322. IF: 2.18, Q1

Mendonça AC, Martins AF, Melchior A, Marques Sérgio M, Chaves S, Villette S, Petoud S, Zanonato PL, Tolazzi M, Bonnet CS, Tóth É, Bernardo P, Geraldes CFGC, Santos MA.     (2013) New Tris-3,4-HOPO lanthanide complexes as potential imaging probes: complex stability and magnetic properties. Dalton Trans., 42, 6046 – 6057. IF: 3.806, Q1

Ramos ML, Sousa ARE, Justino LLG, Fonseca SM, Geraldes CFGC, Burrows HD. (2013) Structural and photophysical studies on Gallium(III) 8-hydroxyquiniline-5-sulphonates. Does excited state decay involve ligand photolabilization? Dalton Trans., 42, 3682-3694. IF: 3.806, Q1

Rajpal A, Dube S, Carvalho F, Simoes AR, Basu A, Figueiredo A, Jones J and Basu R. (2013) Effects of transaldolase on estimates of gluconeogenesis in type 2 diabetes.  Am. J. Physiol. 305: 465-474. IF: 4.51, Q1

Viegas I, Rito J, Gonzalez JD, Jarak I, Carvalho, RA, Meton I, Pardal MA, Baanante IV and Jones JG. (2013) Effects of food-deprivation and refeeding on the regulation and sources of blood glucose appearance in European seabass (Dicentrarchus labrax L.) Comp. Biochem & Physiol. A. 166: 399-405. IF: 2.18, Q1
Abu-Darwish MS, Cabral C, Ferreira IV, Gonçalves MJ, Cavaleiro C, Cruz MT, Al-bdour TH, Salgueiro L. (2013) Essential oil of common sage (Salvia officinalis L.) from Jordan: assessment of safety in mammalian cells and its antifungal and anti-inflammatory potential. Biomed Res Int. 2013:538940. IF: 2,88, Q2

Alçada-Morais S, Sousa AP, Paiva A, Almeida-Santos T & Ramalho-Santos J. (2013) Anterior positioning of sex chromosomes on the head of human sperm sorted using visible wavelengths. Systems Biology in Reproductive Medicine 59: 223-226. IF: 1.9, Q1

Amaral A, Castillo J, Estanyol JM, Ballescà JL, Ramalho-Santos J & Oliva R. (2013) Human sperm tail proteome suggests new endogenous metabolic pathways. Molecular & Cellular Proteomics 12: 330-342. IF: 7.4, Q1

Amaral A, Lourenço B, Marques M & Ramalho-Santos J. (2013) Mitochondria functionality and sperm quality. Reproduction 146: R163–R174. IF: 3.6, Q1

Amaral A & Ramalho-Santos J. (2013) The male gamete is not a somatic cell - the possible meaning of varying sperm RNA levels. Antioxidants & Redox Signaling 18:179-185. IF: 8.5, Q1

Amaral S, Amaral A & Ramalho-Santos J. (2013) Aging and male reproductive function: A mitochondrial perspective Frontiers in Bioscience (Scholar Edition) S5: 181-197. Q1

Amaral S, Redmann K, Sánchez V, Mallidis C, Ramalho-Santos J  & Schlatt S. (2013) UVB irradiation as a tool to assess ROS-induced damage in human sperm. Andrology 1: 707-714. IF: 3, Q1

Baptista M, Publicover SJ  & Ramalho-Santos J. (2013) In vitro effects of cationic compounds on functional human sperm parameters (2013) Fertility and Sterility 99: 705-712. IF:3.8, Q1

Bouzabata A, Bazzali O, Cabral C, Gonçalves MJ, Cruz MT, Bighelli A, Cavaleiro C, Casanova J, Salgueiro L, Tomi F. (2013) New compounds, chemical composition, antifungal activity and cytotoxicity of the essential oil from Myrtus nivellei Batt. & Trab., an endemic species of Central Sahara. J. Ethnopharmacol. 149(3):613-20. IF: 2,755, Q1

Bufalo MC, Ferreira I, Costa G, Francisco V, Liberal J, Cruz MT, Lopes MC, Batista MT, Sforcin JM. (2013) Propolis and its constituent caffeic acid suppress LPS-stimulated pro-inflammatory response by blocking NF-κB and MAPK activation in macrophages. J. Ethnopharmacol. 149(1):84-92. IF: 2,755, Q1

Cabral C, Cavaleiro C, Gonçalves MJ, Cruz MT, Lopes MC, Salgueiro L. (2013) Otanthus maritimus (L.) Hoffmanns. & Link as a source of a bioactive and fragrant oil. Industrial Crops and Products. 43:484-489. IF: 2,468, Q1

Carmo A, Balça-Silva J, Matias D, Lopes MC. (2013). PKC signaling in glioblastomas. Cancer Biology & Therapy, 14 (4): 1-8. IF: 3.287, Q2

Carvalho AS & Ramalho-Santos J. (2013) How can ethics relate to science? The case of stem cell research. European Journal of Human Genetics 21: 591-595. IF: 4.4, Q1

Domingues PH, Teodósio C, Otero A, Sousa P, Gonçalves JM, Nieto AB, Lopes MC, Oliveira CR, Orfao A, Tabernero MD (2013). Association between Inflammatory Infiltrates and Isolated Monosomy 22/del(22q) in Meningiomas. PLOS ONE 8(19): e74798. IF:3,73, Q1

Francisco V, Costa G, Figueirinha A, Marques C, Pereira P, Neves MB, Lopes CeM, García-Rodríguez C, Cruz TM, Batista TM. (2013) Anti-inflammatory activity of Cymbopogon citratus leaves infusion via proteasome and nuclear factor-κB pathway inhibition: contribution of chlorogenic acid. J. Ethnopharmacol.;148(1):126-34. IF: 2,755, Q1

Freitas M, Alves V, Sarmento-Ribeiro AB, Mota-Pinto A. (2013) Polycyclic Aromatic Hydrocarbons May Contribute For Prostate Cancer Progression. J. Cancer Therapy, 4: 37-46.

Gonçalves AC, Alves V, Silva T, Oliveira CR, Sarmento-Ribeiro AB. (2013). Ascorbic and dehydroascorbic acid induce cell death through Oxidative Stress in a human Myelodysplastic Syndrome cell line. Toxicol. in Vitro, 27: 1542–1549.

Gonçalves AC, Ribeiro AB, Alves V, Silva T and Sarmento-Ribeiro AB (2013). Selenium compounds induced ROS-dependent apoptosis in myelodysplasia cells. Biol. Trace Elem. Res.,154:440-447.

Inácio A, Costa G, Santos MS, Moreno AJM, Vaz WLC and Vieira1 OV. (2013) Mitochondrial Dysfunction is the Focus of Quaternary Ammonium Surfactant Toxicity to Mammalian Epithelial Cells. Antimicrobial Agents and Chemotherapy. 57 (6):2631-9. 1Autor de correspondência. IF: 4.565, Q1

Laranjo M, Serra AC., Abrantesa M, Pinheiro M, Gonçalves AC, Casalta-Lopes J, Carvalho L, Sarmento-Ribeiro AB, Rocha-Gonsalves A, Botelho F (2013). 2-Bromo-5-hydroxyphenylporphyrins for photodynamic therapy: Photosensitization efficiency, subcellular localization and in vivo studies. Photodiagnosis and Photodynamic Therapy; 10:51-61.

Mobasheri A, Mendes AF. (2013) Physiology and pathophysiology of musculoskeletal aging: current research trends and future priorities. Front Physiol.;4:73. doi: 10.3389/fphys.2013.00073.

Moura J, da Silva L, Cruz MT, Carvalho E. (2013) Molecular and cellular mechanisms of bone morphogenetic proteins and activins in the skin: potential benefits for wound healing. Arch. Dermatol. Res. 305(7):557-69. IF: 2.7, Q1

Moura LI, Dias AM, Carvalho E*, de Sousa HC*. (2013) Recent advances on the development of wound dressings for diabetic foot ulcer treatment--a review. Acta Biomater. 9(7):7093-114. FI: 5.1, Q1

Moura L, Silva L, Leal EC, Tellechea A, Cruz MT, Carvalho E. (2013) Neurotensin Modulates the Migratory and Inflammatory Response of Macrophages under Hyperglycemic Conditions. Biomed Res. Int. 2013:941764. IF: 2.9, Q2

Neves BM, Rosa SC, Martins JD, Silva A, Gonçalo M, Lopes MC, Cruz MT. (2013) Development of an in vitro dendritic cell-based test for skin sensitizers identification. Chem. Res. Toxicol. 26(3):368-78. IF: 3,667, Q1

Nunes S, Soares E, Fernandes J, Viana S, Carvalho E, Pereira FC, Reis F. (2013) Early cardiac changes in a rat model of prediabetes: brain natriuretic peptide overexpression seems to be the best marker. Cardiovasc Diabetol. 12(1):44. IF: 4.2, Q1

Pereira SL, Grãos M, Rodrigues AS, Anjo SI, Carvalho RA, Oliveira PJ , Arenas E  & Ramalho-Santos J. (2013) Inhibition of mitochondrial complex III blocks neuronal differentiation and maintains embryonic stem cell pluripotency. PLoS ONE 8:e82095. IF: 4.4, Q1

Pereira SP, Pereira GC, Pereira CV, Carvalho FS, Cordeiro M, Mota PC,  Ramalho-Santos J, Moreno AJ & Oliveira PJ. (2013) In vivo effects of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) on heart and liver mitochondria: Role of ATP-dependent potassium channels. Environmental Pollution 180: 281-290. IF: 3.7, Q1

Ramalho-Santos J & Amaral S. (2013) Mitochondria and mammalian reproduction. Molecular and Cellular Endocrinology 379: 74-84. IF: 4.0, Q1

Resende M, Moreira D, Augusto J, Cunha J, Neves B, Cruz MT, Estaquier J, Cordeiro-da-Silva A, Silvestre R. (2013) Leishmania-Infected MHC Class IIhigh Dendritic Cells Polarize CD4+ T Cells toward a Nonprotective T-bet+ IFN-γ+ IL-10+ Phenotype. J. Immunol. 191(1):262-73. IF: 5,52, Q1

Rufino AT, Rosa SC, Judas F, Mobasheri A, Lopes MC, Mendes AF. (2013) Expression and function of K(ATP) channels in normal and osteoarthritic human chondrocytes: possible role in glucose sensing. J Cell. Biochem. 114:1879–1889. IF: 3.062, Q2

Santinha D. Dória ML, Neves BM, Maciel EA, Martins J, Helguero L, Domingues P, Cruz MT, Domingues MR. (2013) Prospective phospholipid markers for skin sensitization prediction in keratinocytes: A phospholipidomic approach. Archives of Biochemistry and Biophysics 533, 33–41. IF: 3,37, Q2

Tavares RS, Mansell S, Barratt CL, Wilson SM, Publicover SJ & Ramalho-Santos J. (2013) p,p’-DDE activates CatSper and compromises human sperm function at environmentally-relevant concentrations. Human Reproduction 28: 3167-3177. IF: 4.7, Q1

Tavares RS, Silva AF, Lourenço B, Almeida-Santos T, Sousa AP & Ramalho-Santos J. (2013) Evaluation of human sperm chromatin status after selection using a modified Diff-Quik stain indicates embryo quality and pregnancy outcomes following in vitro fertilization. Andrology 1: 830-837. IF: 3, Q1

Tecilazich F, Dinh T, Pradhan L, Leal E, Tellechea A, Kafanas A, Gnardellis C, Toxavidis V, Tigges C, Carvalho E, Lyons T, Veves A. (2013) Role of Endothelial Progenitor Cells and Inflammatory Cytokines in Healing of Diabetic Foot Ulcers. PLoS One. 8(12):e83314. IF: 3.7, Q1

Valente J, Zuzarte M, Gonçalves MJ, Lopes MC, Cavaleiro C, Salgueiro L, Cruz MT. (2013) Antifungal, antioxidant and anti-inflammatory activities of Oenanthe crocata L. essential oil. Food Chem. Toxicol.;62C:349-354. IF: 3,01, Q1

Valente J, Zuzarte M, Liberal J, Gonçalves MJ, Lopes MC, Cavaleiro C, Cruz MT, Salgueiro L. (2013) Margotia gummifera essential oil as a source of anti-inflammatory drugs. Industrial Crops and Products. 47: 86– 91. IF: 2,468, Q1

Wardah Alasmari, Sarah Costello, João Correia, Senga Oxenham, Jennifer Morris, Leonor Fernandes, João Ramalho-Santos, Jackson Kirkman-Brown, Francesco Michelangeli, Stephen Publicover & Christopher Barratt. (2013) Ca2+ signalling through CatSper and Ca2+ stores generate different behaviours in human sperm. Journal of Biological Chemistry 288: 6248-6258. IF: 4.8, Q1

Zuzarte M, Gonçalves MJ, Cavaleiro C, Cruz MT, Benzarti A, Marongiu B, Maxia A, Piras A, Salgueiro L. (2013) Antifungal and anti-inflammatory potential of Lavandula stoechas and Thymus herba-barona essential oils. Industrial Crops and Products, 44, 97-103. IF: 2,468, Q1
Almeida L, Rocha JF, Falcão AC, Palma PN, Loureiro AI, Pinto R, Bonifácio MJ, Wright LC,  Nunes T. Soares-da-Silva P. (2013) Pharmacokinetics, Pharmacodynamics and Tolerability of Opicapone, a Novel Catechol-O-Methyltransferase Inhibitor, in Healthy Subjects: Prediction of Slow Enzyme-Inhibitor Complex Dissociation of a Short-Living and Very Long-Acting Inhibitor. Clinical Pharmacokinetics, 52(2):139-151. Q1

Alves G, Rodrigues M, Fortuna A, Falcão AC, Queiroz J (2013) A critical review of microextraction by packed sorbent as a sample preparation approach in drug bioanalysis. Bioanalysis, 5(11): 1409-1442. Q1

Bento D, Borchard G, Gonçalves T, Borges O. (2013) Validation of a new spectrophotometric method for the qualification of compound 48/80 associated with nanoparticles. AAPS PharSciTech. 14(2):649-655. IF: 1.9, Q1
Bicker J, Fortuna A, Alves G, Falcão AC. (2013) Liquid chromatographic methods for the quantification of catecholamines and their metabolites in several biological samples–A review. Analytica Chimica Acta, 768: 12-34. Q1

Calejo MT, Cardoso AMS, Kjøniksena AL, Zhub K, Morais CM, Sandea SA, Cardoso AL, Pedroso de Lima MC,  Jurado A, Nyström B. (2013) Temperature-Responsive Cationic Block Copolymers as Nanocarriers for Gene Delivery. International Journal of Pharmaceutics 448 (1), 105-14. IF: 3.45, Q1

Calejo MT, Cardoso AMS, Marques EF, Araújo MJ, Kjøniksen AL, Sande SA, de Lima MCP, Jurado AS, and Nyström B. (2013) In vitro cytotoxicity of a thermoresponsive gel system combining ethyl(hydroxyethyl) cellulose and lysine-based surfactants. Colloids and Surfaces B: Biointerfaces 102 (0), 682-686. IF: 3.35, Q2

Cardoso AM, Trabulo S, Cardoso AL, Maia S, Gomes P, Jurado AlS, and Pedroso de Lima MC. (2013) Comparison of the Efficiency of Complexes Based on S413-PV Cell-Penetrating Peptides in Plasmid DNA and siRNA Delivery. Molecular Pharmaceutics 10 (7), 2653-2666. IF: 4.57, Q1

Correia D, Pereira C, Veríssimo P, Dourado A. (2013) A Platform for Peptidase Detection Based on Text Mining Techniques and Support Vector Machines. Computational Intelligence and Decision Making, 449-459.

Costa PM, Cardoso AL, Mendonça LS, Serani A, Custódia C, Conceição M, Simões S, Moreira JN, Pereira de Almeida L, Pedroso de Lima MC. (2013) Tumor-targeted chlorotoxin-coupled nanoparticles for nucleic acid delivery to glioblastoma cells: a promising system for glioblastoma treatment. Molecular Therapy  2:e100.  IF: 7.04, Q1

Costa PM, Cardoso AL, Nóbrega C, Pereira de Almeida LF, Bruce JN, Canoll P, and Pedroso de Lima MC. (2013) microRNA-21 silencing enhances the cytotoxic effect of the antiangiogenic drug sunitinib in glioblastoma. Human Molecular Genetics,  22 (5) 904-18. IF: 7.69; Q1

Costa PM and Pedroso de Lima MC. (2013) MicroRNAs as molecular targets for cancer therapy: on the modulation of miRNA expression. Pharmaceuticals, 6(10):1195-1220.

Costa PM and Pedroso de Lima MC. (2013) Viral and non-viral gene therapy for glioblastoma: new insights into the treatment of malignant brain tumors. Journal of Genetic Syndromes & Gene Therapy, 4:161 .

Duarte S, Momier D, Baqué P, Casanova V, Loubat A, Samson M, Guigonis JM, Staccini P, Saint-Paul MC , Pedroso de Lima MC, Carle GF and Pierrefite Carle V.  (2013) Preventive cancer stem cell-based vaccination reduces liver metastasis development in a rat colon carcinoma syngeneic model. Stem Cells, 31 423-432. IF: 7.7, Q1

Duarte SC, Almeida AM, Teixeira AS, Pereira AL, Falcão AC, Pena A, Lino CM. (2013) Aflatoxin M1 in marketed milk in Portugal: assessment of human and animal exposure. Food Control, 30:411-417. Q1

Falcão AC, Lima R, Sousa R, Nunes T, Soares-da-Silva P. (2013) Bioequivalence of Eslicarbazepine Acetate from Two Different Sources of its Active Product Ingredient in Healthy Subjects. Drugs in R&D, 13: 137-143.

Falcão AC, Pinto R, Nunes T, Soares-da-Silva P. (2013) Effect of repeated administration of eslicarbazepine acetate on the pharmacokinetics of simvastatin in healthy subjects. Epilepsy Research, 106: 244-249.

Falcão AC, Vaz-da-Silva M, Gama H, Nunes T,  Almeida L, Soares-da-Silva P. (2013) Effect of eslicarbazepine acetate on the pharmacokinetics of a combined ethinylestradiol/levonorgestrel oral contraceptive in healthy women. Epilepsy Research, 105: 368-376.

Figueiredo S, Cutri JC, Rizzitelli S, De Luca E, Geraldes CF, Moreira JN, Aime S, Terreno E. (2012) MRI tracking of macrophages labeled with glucan particles entrapping a Water Insoluble Paramagnetic Gd-Based Agent. Molecular Imaging and Biology, (3):307-15 (2013).  IF: 3.844, Q1

Gil-Nager A, Elger C, Ben-Menachem E, Haláz P, Lopes-Lima J, Gabbai AA, Nunes T, Falcão AC, Almeida L, Soares-da-Silva P. (2013) Efficacy and safety of eslicarbazepine acetate as add‐on treatment in patients with focal‐onset seizures: Integrated analysis of pooled data from double‐blind phase III clinical studies. Epilepsia, 54(1):98-107. Q1

Gomes CP, Gomes-da-Silva LC, Ramalho JS, Pedroso de Lima MC, Simões S, Moreira JN. (2013) Impact of PLK-1 silencing on endothelial cells and cancer cells of diverse histological origin. Current Gene Therapy, 13(3):189-201. IF: 5.318; Q1

Gomes-da-Silva LC, Ramalho JS, Pedroso de Lima MC, Simões S, Moreira JN. (2013) Efficient intracellular delivery of siRNA with a safe multitargeted lipid-based nanoplatform. European Journal of Pharmaceutics and Biopharmaceutics, 85(3 Pt A):356-364. IF: 3.826, Q1

Gomes-da-Silva LC, Fernández Y, Abasolo I, Schwartz Jr S, Ramalho JS, Pedroso de Lima MC, Simões S, Moreira JN. (2013) Efficient intracellular delivery of siRNA with a safe multitargeted lipid-based nanoplatform. Nanomedicine, 8(9):1397-413.  IF: 5.26, Q1

Gomes RSM, Neves R, Cochlin L, Lima AF, Carvalho R, Korpisalo P, Dragneva G, Turunen M, Liimatainen T, Clarke K, Yla-Herttuala S, Carr CA, Ferreira L. (2013) Nanoparticles for simultaneous cell tracking and pro-survival/angiogenic miRNA delivery in an ischemic animal model. ACS Nano, 7(4), 3362-3372. IF: 12.0, Q1

Gonçalves D, Alves G, Fortuna A, Soares-da-Silva P, Falcão AC. (2013) HPLC-DAD method for the simultaneous quantification of opicapone (BIA 9-1067) and its active metabolite in human plasma. Analyst, 138(8): 2463-2469. Q1
Guedes J, Cardoso AL, Pedroso de Lima MC. (2013) MicroRNA involvement in microglia-mediated immune response. Clinical and Developmental Immunology – Special Issue “Microglia in Development and Disease”.  article ID 186872. IF: 3.06, Q2

Hufnagel A, Menachem B, Gabbai AA, Falcão AC, Almeida L, Soares-da-Silva P. (2013) Long-term safety and efficacy of eslicarbazepine acetate as adjunctive therapy in the treatment of partial-onset seizures in adults with epilepsy: Results of a 1-year open-label extension study. Epilepsy Research, 103(2-3):262-269.

Jesus S, Borchard G, Borges O. (2013) Freeze dried chitosan/poly-epsilon-caprolactone and poly-epsilon-caprolactone nanoparticles: evaluation of their potential as DNA and antigen delivery system. Journal of Genetic Syndromes & Gene Therapy, 4:164.

Leal AS, Wang R, Salvador JAR, Jing YK. (2013) Synthesis of novel heterocyclic oleanolic acid derivatives with improved antiproliferative activity in solid tumor cells. Org. Biomol. Chem. 11, 1726-1738. IF: 3.568, Q1

Lino MM*, Paulo CSO*, Vale AC, Vaz MF, Ferreira LS. (2013) Antifungal activity of dental resins containing amphotericin B-functionalized silica nanoparticles. Dental Materials, 29(10): e252-62. *Authors contributed equally. IF: 3.7, Q1

Monteiro JP, Martins AF, Nunes C, Morais CM, Lúcio, M, Reis S, Pinheiro TJT, Geraldes CFGC, Oliveira PJ, and Jurado AS. (2013) A biophysical approach to menadione membrane interactions: Relevance for menadione-induced mitochondria dysfunction and related deleterious/therapeutic effects. Biochimica et Biophysica Acta (BBA) - Biomembranes 1828 (8), 1899-1908. IF: 3.38, Q1

Monteiro JP, Oliveira PJ, and Jurado AS. (2013) Mitochondrial membrane lipid remodeling in pathophysiology: A new target for diet and therapeutic interventions. Progress in Lipid Research 52 (4), 513-528. IF: 10.25, Q1

Moreira VM, Salvador JA, Simões S, Destro F, Gavioli R. (2013) Novel oleanolic vinyl boronates: synthesis and antitumor activity. Eur. J. Med. Chem. 63:46-56. IF:3,499, Q1

Morgado L, Pereira C, Veríssimo P, Dourado A. (2013) Efficient Discriminative Models for Proteomics with Simple and Optimized Features. Computational Intelligence and Decision Making, 89-98.

Nascimento-Ferreira I, Nóbrega C, Vasconcelos-Ferreira A, Onofre I, Albuquerque D, Aveleira C, Hirai H, Déglon N, Pereira de Almeida L. (2013) Beclin-1 mitigates motor and neuropathological deficits in genetic mouse models of Machado-Joseph disease. Brain DOI: 10.1093/brain/awt144. IF: 9.9, Q1

Nóbrega C*, Nascimento-Ferreira I*, Onofre I, Albuquerque D,  Hirai H, Déglon N,  Pereira de Almeida L.  (2013) Silencing Mutant Ataxin-3 Rescues Motor Deficits and Neuropathology in Machado-Joseph Disease Transgenic Mice. PLoS ONE 8(1): e52396. doi:10.1371/journal.pone.0052396 *Equal contribution. DOI: 10.1371/journal.pone.0052396. IF: 3.7, Q1

Nóbrega C*, Nascimento-Ferreira I*, Onofre I, Albuquerque D, Conceição M, Déglon N,  Pereira de Almeida L. (2013) Overexpression of mutant ataxin-3 in mouse cerebellum induces ataxia and cerebellar neuropathology. Cerebellum 12(4):441-55 doi:10.1007/s12311-012-0432-0. *Equal contribution. IF: 2.6, Q3

Nunes T, Rocha JF, Falcão AC, Almeida L, Soares-da-Silva P. (2013) Steady-state plasma and cerebrospinal fluid pharmacokinetics and tolerability of eslicarbazepine acetate and oxcarbazepine in healthy volunteers. Epilepsia, 54(1):108-116. Q1

Oliveira J, Correia D, Pereira C, Veríssimo P, Dourado A. (2013)A Tool for Biomedical–Documents Classification Using Support Vector Machines. Computational Intelligence and Decision Making, 407-416.

Paiva G, Proença DN, Francisco R,Veríssimo P, Santos S, Fonseca L, Abrantes IMO, Morais PV. (2013) Nematicidal Bacteria Associated to Pinewood Nematode Produce Extracellular Proteases. PLoS One 8(11):e79705 DOI: 10.1371/journal.pone.0079705.

Paulo CSO*, Lino MM*, Matos AA, Ferreira LS. (2013) Nanoparticles conjugated with amphotericin B are differentially taken up by human cells and after internalization increase the expression of heat shock protein. Biomaterials, 34(21), 5281-5293. *Authors contributed equally. IF: 7.6, Q1

Pereira MJ, Oyuang B, Sarkar D, Lang N, Sunbdback C, Fiehs I, Mureli S, Pometantseva I, McFaden J, Sehn JD, Mwizerwa O, del Nido P, Masiakos P, Langer R, Ferreira LS*, Karp JM*. (2013) A highly tunable elastomer for local and controlled release of macromolecular therapeutics. Advanced Materials, 25(8), 1209-1215. *Authors contributed equally. IF: 14.8, Q1

Ricotti L, Fujie T, Vazão H, Ciofani G, Filippeschi C, Corradini I, Matteoli M, Mattoli V, Ferreira L, Menciassi A. (2013) Boron nitride nanotube-mediated stimulation of cell co-culture on microengineered hydrogels. PLoS One 8(8), e71707. IF: 3.7, Q1

Rocha JF, Almeida L, Falcão AC, Nuno P, Loureiro AI,  Pinto R, Bonifácio MJ, Wright L, Nunes T, Soares-da-Silva P. (2013) Opicapone: a short lived and very long acting novel catechol-O-methyltransferase inhibitor following multiple dose administration in healthy subjects. British Journal of Clinical Pharmacology, 76(5): 763-775. Q1

Rodrigues AT, Roque F, Abrantes J, Falcão AC, Figueiras A, Herdeiro MT. (2013) Understanding physician antibiotic prescribing behaviour: a systematic review of qualitative studies. International Journal of Antimicrobial Agents, 41(3): 203-212.

Rodrigues M, Alves G, Abrantes J, Falcão AC. (2013) Herb-drug interaction of Fucus vesiculosus extract and amiodarone in rats: a potential risk for reduced bioavailability of amiodarone in clinical practice. Food and Chemical Toxicology, 52: 121-128. Q1

Rodrigues M, Alves G, Falcão AC. (2013) Investigating herb-drug interactions: the effect of Citrus aurantium fruit extract on the pharmacokinetics of amiodarone in rats. Food and Chemical Toxicology, 60: 153–159. Q1

Rodrigues M, Alves G, Rocha M, Queiroz J, Falcão AC. (2013) First liquid chromatographic method for the simultaneous determination of amiodarone and desethylamiodarone in human plasma using microextraction by packed sorbent (MEPS) as sample preparation procedure. Journal of Chromatographic B, 913-914: 90-97.

Salvador JAR, Carvalho JFS,  Neves MAC, Silvestre MS, Leitão A J, Silva MMC,  Sá e Melo M L (2013) Anticancer steroids: linking natural and semi-synthetic compounds. Nat. Prod. Rep., 30 (2), 324-374. IF: 10.178, Q1

Salvador JAR, Pinto RMA, Silvestre SM. (2013) Steroidal 5 alpha-reductase and 17 alpha-hydroxylase/17,20-lyase (CYP17) inhibitors useful in the treatment of prostatic diseases. J. Steroid Biochem. Mol. Biol. 137, 199-222. IF: 3.984, Q2

Santos SM, Dinis AM, Peixoto F, Ferreira L, Jurado AlS, and Videira RA. (2013) Interaction of fullerene nanoparticles with biomembranes: from the partition in lipid membranes to effects on mitochondrial bioenergetics. Toxicological Sciences, IF: 4.32, Q1

Santos SM, Dinis AM, Rodrigues DM, Peixoto F, Videira RA, and Jurado AS. (2013) Studies on the toxicity of an aqueous suspension of C60 nanoparticles using a bacterium (gen. Bacillus) and an aquatic plant (Lemna gibba) as in vitro model systems. Aquat. Toxicol. 142-143 347-354. IF: 3.73, Q1

Silva SG, Alves C, Cardoso AMS, Jurado AS, Pedroso de Lima MC, Vale MLC, and Marques EF. (2013) Synthesis of Gemini Surfactants and Evaluation of Their Interfacial and Cytotoxic Properties: Exploring the Multifunctionality of Serine as Headgroup. European Journal of Organic Chemistry, (9), 1758-1769. IF: 3,4, Q1

Sousa J, Alves G, Campos G, Fortuna A, Falcão AC. (2013) First liquid chromatography method for the simultaneous determination of levofloxacin, pazufloxacin, gatifloxacin, moxifloxacin and trovafloxacin in human plasma. Journal of Chromatography B, 930: 104-111.

Toubarro D, Avila MM, Hao YJ, Balasubramanian N, Jing Y, Montiel R, Faria TQ. Brito RMM, and Simões N. (2013) A Serpin Released by an Entomopathogen Impairs Clot Formation in Insect Defense System. PLoS One 8(7): e69161. IF: 3.730, Q1

Trabulo S, Cardoso AL, Cardoso AM, Morais CM, Jurado AS, and Pedroso de Lima MC. (2013) Cell penetrating peptides as nucleic acid delivery systems: from biophysics to biological applications. Current Pharmaceutical Design, 19 (16) 2895-923. IF: 3.3, Q1
Alves MG, Rato L, Carvalho RA, Moreira PI, Socorro S, Oliveira PF. (2013) Hormonal control of Sertoli cell metabolism regulates spermatogenesis. Cell. Mol. Life Sci. 70 (5), 777-793. IF: 5.6, Q1

Burgeiro A, Gajate C, Oliveira PJ, Mollinedo F. (2013) Rapid Human Melanoma Cell Death Induced by Sanguinarine Through Oxidative Stress. Eur. J. Pharmacol. 705 (1-3):109-118. IF: 2.6, Q2

Ferreira NR, Santos RM, Laranjinha J and Barbosa RM (2013) Real time in vivo measurement of ascorbate in the brain using carbon nanotube-modified microelectrodes. Electroanalysis 25, 1757-1763.

Figueiras E, Oliveira R, Lourenço CF, Campos R, Humeau-Heurtier A, Barbosa RM, Laranjinha J, Requicha Ferreira LF, de Mul FF. (2013) Self-mixing microprobe for monitoring microvascular perfusion in rat brain. Med Biol. Eng. Comput. 51, 103-112.

Gomes AP, Price NL, Ling AJ, Moslehi JJ, Montgomery MK, Rajman L, White JP, Teodoro JS, Wrann CD, Hubbard BP, Mercken EM, Palmeira CM, de Cabo R, Rolo AP, Turner N, Bell EL, Sinclair DA. (2013) Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging.  Cell 155(7):1624-38. IF: 31.957, Q1

Hubbard BP, Gomes AP, Dai H, Li J, Case AW, Considine T, Riera TV, Lee JE, E SY, Lamming DW, Pentelute BL, Schuman ER, Stevens LA, Ling AJ, Armour SM, Michan S, Zhao H, Jiang Y, Sweitzer SM, Blum CA, Disch JS, Ng PY, Howitz KT, Rolo AP, Hamuro Y, Moss J, Perni RB, Ellis JL, Vlasuk GP, Sinclair DA. (2013) Evidence for a common mechanism of SIRT1 regulation by allosteric activators.  Science 339(6124):1216-9. IF: 31.03, Q1

Lebiedzinska M, Karkucinska-Wieckowska A, Wojtala A, Suski JM, Szabadkai G, Wilczyński G, Wlodarczyk J, Diogo CV, Oliveira PJ, Tauber J, Ježek P, Pronicki P, Duszynski J, Pinton P, Wieckowski MR. (2013) Disrupted ATP Synthase Activity and Mitochondrial Hyperpolarisation- dependent Oxidative Stress is Associated with p66Shc Phosphorylation in Fibroblasts of NARP patients. Int. J. Biochem. Cell Biol. 45(1):141-150. IF: 4.2, Q2

Lino FMA, de Sá LZ, Torres IMS, Rocha ML, Dinis TCP, Ghedini PC, Somerset VS, Gil ES. (2013) Voltammetric and spectrometric determination of antioxidant capacity of selected wines. Electrochim. Acta 128: 25-31. IF: 3.777, Q1

Magalhães J, Falcão-Pires I, Gonçalves IO, Lumini-Oliveira J, Marques-Aleixo I, Passos E, Rocha-Rodrigues S, Machado NG, Moreira AC, Miranda-Silva D, Moura C, Leite-Moreira A, Oliveira PJ, Torrella JR, Ascensão A. (2013) Synergistic Impact of Endurance Training and Intermittent Hypobaric Hypoxia on Cardiac Function and Mitochondrial Energetic and Signaling. Int. J. Cardiol., 168(6):5363-71. IF: 5.5, Q1

Monteiro JP, Maciel E, Peixoto F, Domingues MR, Jurado AS, Oliveira PJ. (2013) Rapeseed Oil-rich Diet Alters Hepatic Mitochondrial Membrane Lipid Composition and Disrupts Bioenergetics. Arch. Toxicol., 87 (12): 2151-2163. IF: 5.2, Q1

Monteiro JP, Silva AM, Jurado AS, Oliveira PJ. (2013) Rapeseed Oil-rich Diet Alters in vitro Menadione and Nimesulide Hepatic Mitochondrial Toxicity. Food Chem. Toxicol. 60: 479-487. IF: 3.0, Q1

Moreira AC, Silva AM, Santos MS, Sardao VA. (2013) Resveratrol Affects Differently Rat Liver and Brain Mitochondrial Bioenergetics and Oxidative Stress in vitro: Investigation of the Role of Gender. Food and Chemical Toxicology 53:18-26. IF: 3.0, Q1

Nunes C, Ferreira E, Freitas V, Almeida L, Barbosa RM, Laranjinha J. (2013) Intestinal anti-inflammatory activity of red wine extract: unveiling the mechanisms in colonic epithelial cells. Food and Function 4, 373-383.

Oliveira SC, Santarino IB, Enache TA, Nunes C, Laranjinha J, Barbosa RM and Oliveira-Brett AM (2013) Human cólon adenocarcinoma HT-29 cell: electrochemistry and nicotine stimulation. Bioelectrochemistry 94c, 30-38.

Pereira C, Ferreira NR, Rocha BS, Barbosa RM, and Laranjinha J (2013) The redox interplay between nitrite and nitric oxide: from the gut to the brain. Redox Biol. 1, 276-284.

Pereira SP, Pereira GC, Pereira CV, Carvalho FS, Cordeiro MH, Mota PC, Ramalho-Santos J, Moreno AJ, Oliveira PJ. (2013) Dioxin-induced Cardiac Mitochondrial Oxidative Damage and Increased Activity of ATP-sensitive Potassium Channels. Environm. Polut. 180:281-90. IF: 3.7, Q1

Pereira RFP, Valente AJM, Burrows HD, Bermudez VZ, Carvalho RA, Castro RAE. (2013) Structural characterization of solid trivalent metal dodecyl sulfates: from aqueous solution to lamellar superstructures. RSC Advances 3 (5), 1420-1433. IF: 2.6, Q1

Ribeiro MP, Santos AE, Santos MS, Custódio JB. (2013) Effects of all-trans-retinoic acid on the permeability transition and bioenergetic functions of rat liver mitochondria in combination with endoxifen. Life Sci., 93 (2-3): 96-107. IF: 2.6, Q2

Ribeiro MP, Silva FS, Santos AE, Santos MS, Custódio JB. (2013) The antiestrogen endoxifen protects rat liver mitochondria from permeability transition pore opening and oxidative stress at concentrations that do not affect the phosphorylation efficiency. Toxicol. Appl. Pharmacol., 267 (1): 104-112. IF: 4.0, Q1

Ribeiro MP, Silva FS, Paixão J, Santos AE, Custódio JB. (2013) The combination of the antiestrogen endoxifen with all-trans-retinoic acid has anti-proliferative and anti-migration effects on melanoma cells without inducing significant toxicity in non-neoplasic cells. Eur. J. Pharmacol., 715 (1-3): 354-362. IF: 2.6, Q2

Rocha BS, Gago B, Barbosa RM, Lundberg JO, Mann GE, Radi R, Laranjinha J. (2013) Pepsin is nitrated in the rat stomach acquiring antiulcerogenic activity: a novel interaction between dietary nitrate and gut proteins. Free Radic. Biol. Med. 58, 26-34.

Rossato LG, Costa VM, de Pinho PG, Arbo MD, de Freitas V, Vilain L, de Lourdes Bastos M, Palmeira C, Remião F. (2013) The metabolic profile of mitoxantrone and its relation with mitoxantrone-induced cardiotoxicity. Arch. Toxicol. 87(10):1809-20. IF: 5.215, Q1

Santos RM, Rodrigues MS, Laranjinha J and Barbosa RM (2013) Biomimetic sensor based on hemin/carbon nanotubes/chitosan modified microelectrode for nitric oxide measurement in the brain. Biosensors and Bioelectronics 44, 152-159.

Serra D, Paixão J, Nunes C, Dinis TCP, Almeida LM, Cyanidin-3-glucoside suppresses cytokine-induced inflammatory response in human intestinal cells: comparison with 5-aminosalicylic acid. PLoS One (2013) 8(9):e73001, 9pg. IF: 5.271, Q1

Silva FS, Ribeiro MP, Santos MS, Rocha-Pereira P, Santos-Silva A, Custódio JB. (2013) Acitretin affects bioenergetics of liver mitochondria and promotes mitochondrial permeability transition: Potential mechanisms of hepatotoxicity. Toxicology 306: 93-100. IF: 4.0, Q1
Alarico S, Empadinhas N, da Costa MS. (2013) A new bacterial hydrolase specific for the compatible solutes alpha-D-mannopyranosyl-(1→2)-D-glycerate and alpha-D-glucopyranosyl-(1→2)-D-glycerate. Enzyme and Microbial Technology 52(2):77-83. IF: 2.59, Q1

Albuquerque L, Rainey FA, Nobre MF & da Costa MS.  (2013) Oceanicella artignis gen. nov., sp. nov., A Halophilic Slightly Thermophilic Member of the Alphaproteobacteria. Systematic and Applied Microbiology 35:385-389.

Albuquerque L, Taborda M, La Cono V, Yakimov M & da Costa MS. (2013) Natrinema salaciae sp. nov., a halophilic archaeon isolated from the deep, hypersaline anoxic Lake Medee in the Eastern Mediterranean Sea. Systematic and Applied Microbiology, 35:368-373.

Albuquerque L, Tiago I, Nobre MF, Veríssimo A & da Costa MS. (2013) Cecembia calidifontis sp. nov., a novel bacterium from a hot spring runoff in the Azores and emended description of the genus Cecembia. International Journal of Systematic and Evolutionary Microbiology, 63:1431-1436.

Bowman KS, Nobre MF, da Costa MS, Rainey FA & Moe WM. (2013) Dehalogenimonas alkenigignens sp. nov., a chlorinated alkane dehalogenating bacterium isolated from groundwater. International Journal of Systematic and Evolutionary Microbiology, 63:1492-1498.

Cunha S, d’Avó AF, Mingote A, Lamosa P, da Costa MS, & Costa J. (2013) Mannosylglucosylglycerate biosynthesis in the deep-branching phylum Planctomycetes: characterization of the uncommon enzymes from Rhodopirellula baltica. Scientific Reports, 3: 2378, doi:10.1038/srep02378.

d’Avó AF, Cunha S,  Mingote A, Lamosa P, da Costa MS, & Costa J. (2013) A unique pool of compatible solutes on Rhodopirellula baltica, member of the deep branching phylum Planctomycetes. PloS One, 27: e68289.

Leandro T, França L, Nobre MF, Rainey FA, & da Costa MS.  (2013) Heliimonas saccharivorans gen. nov., sp. nov., a member of the family Chitinophagaceae isolated from a mineral water aquifer and emended description of Filimonas lacunae. International Journal of Systematic and Evolutionary Microbiology, 63: 3793-3799.

Marques J, Paula A, Gonçalves T, Ferreira M, Carrilho E. (2013) Ozone action on Streptococcus mutans and Lactobacillus fermentum: A pilot study. World J. Stomatol. 2(1): 18-23. doi:10.5321/wjs.v2.i1.18.

Miranda I, Silva-Dias A, Rocha R, Teixeira-Santos R, Coelho C, Gonçalves T, Santos MAS, Pina-Vaz C, Solis NV, Filler SG, Rodrigues AG. (2013) Candida albicans CUG Mistranslation Is a Mechanism To Create Cell Surface Variation. mBio 4(4). pii: e00285-13. doi: 10.1128/mBio.00285-13. IF: 5.6, Q1

Nobre A, Empadinhas N, Nobre MF, Lourenço EC, Maycock CD, Ventura MR, Mingote A, & da Costa MS.  (2013) The plant Selaginella moellendorffii possesses enzymes for the synthesis and hydrolysis of the compatible solutes mannosylglycerate and glucosylglycerate. Planta, 237:891-901

Pereira SG, Albuquerque L, Nobre MF, Tiago I, Veríssimo A, Pereira A, and da Costa MS. (2013). Pullulanibacillus uraniitolerans sp. nov., a new acidophilic, U (VI)-resistant species isolated from an acid uranium mill tailing effluent and emended description of the genus Pullulanibacillus. Int. J. Syst. Evol. Microbiol. 63:158-162. 

Silva BMA, Prados-Rosales R, Espadas-Moreno J, Wolf JM, Luque-Garcia JL, Gonçalves T, Casadevall A. (2013) Characterization of Alternaria infectoria extracellular vesicles. Medical Mycology 52 (2): 202-210. doi: 10.1093/mmy/myt003. IF: 2.168, Q1

Tiago I and Verissimo A. (2013) Microbial and functional diversity of a subterrestrial high pH groundwater associated to serpentinization. Environ. Microbiology 15(6), 1687–1706.
Aguiar ASJr, Moreira ELG, Hoeller AA, Oliveira PA, Córdova FM, Glazer V, Walz R, Cunha RA, Leal RB, Latini A, Prediger RD. (2013) Exercise attenuates L-DOPA-induced dyskinesias in 6-OHDA-lesioned mice. Neuroscience 243, 46-53. IF: 3.122, Q2

Alves MG, Martins AD, Rato L, Moreira PI, Socorro S, Oliveira PF. (2013) Molecular mechanisms beyond glucose transport in diabetes-related male infertility. Biochim. Biophys. Acta 1832(5):626-35. doi: 10.1016/j.bbadis.2013.01.011. Review, IF:4.91, Q1

Alves MG, Neuhaus-Oliveira A, Moreira PI, Socorro S, Oliveira PF. (2013) Exposure to 2,4-dichlorophenoxyacetic acid alters glucose metabolism in immature rat Sertoli cells. Reprod. Toxicol. 38:81-8. IF: 3.141, Q2

Arduino DM, Esteves AR, Cardoso SM. (2013) Mitochondria drive autophagy pathology via microtubule disassembly: a new hypothesis for Parkinson disease. Autophagy 9(1):112-4. IF: 12.042, Q1

Augusto E, Matos M, Sévigny J, El-Tayeb A, Bynoe MS, Muller CE, Cunha RA, Chen JF. (2013) Ecto-5´-nucleotidase (CD73)-mediated formation of adenosine is critical for the striatal adenosine A2A receptor functions. J. Neurosci. 33, 11390-11399. IF: 6.908, Q1

Baptista FI, Pinto MJ, Elvas F, Almeida RD, Ambrósio AF. (2013) Diabetes alters KIF1A and KIF5B motor proteins in the hippocampus. PLoS One 12;8(6):e65515. IF: 3.730, Q1

Caldeira GL, Ferreira IL, Rego AC. (2013) Impaired transcription in Alzheimer´s disease – key role in mitochondrial dysfunction and oxidative stress. J Alzheimers Dis. 34, 115-131. Review, IF: 4.174, Q2

Caldeira MV, Curcio M, Leal G, Salazar IL, Mele M, Santos AR, Melo CV, Pereira P, Canzoniero LM, Duarte CB. (2013) Excitotoxic stimulation downregulates the ubiquitin-proteasome system through activation of NMDA receptors in cultured hippocampal neurons. Biochim. Biophys. Acta 1832, 263-274. IF: 4.910, Q1

Cardoso S, Correia SC, Santos RX, Carvalho C, Candeias E, Duarte AI, Plácido AI, Santos MS, Moreira PI. (2013) Hyperglycemia, hypoglycemia and dementia: role of mitochondria and uncoupling proteins. Curr. Mol. Med. 13(4):586-601. Review, IF: 4.197, Q1

Cardoso S, Santos MS, Moreno A, Moreira PI. (2013) UCP2 and ANT differently modulate proton-leak in brain mitochondria of long-term hyperglycemic and recurrent hypoglycemic rats. J. Bioenerg. Biomembr. 45(4):397-407. IF: 1.604, Q4

Carreira BP, Morte MI, Lourenço AS, Santos AI, Inácio Â, Ambrósio AF, Carvalho CM, Araújo IM (2013) Differential contribution of the guanylyl cyclase-cyclic GMP-Protein kinase G pathway to the proliferation of neural stem cells stimulated by nitric oxide. Neurosignals 21:1-13. IF: 2.561, Q2

Carvalheiro H, da Silva JA, Souto-Carneiro MM. (2013) Potential roles for CD8(+) T cells in rheumatoid arthritis. Autoimmun. Rev. 12(3):401-9.

Carvalho C, Machado N, Mota PC, Correia SC, Cardoso S, Santos RX, Santos MS, Oliveira CR, Moreira PI. (2013) Type 2 diabetic and Alzheimer´s disease mice present similar behavioral, cognitive, and vascular anomalies. J. Alzheimers Dis. 35(3):623-35. IF: 4.17), Q2

Catarino T, Ribeiro L, Santos SD, Carvalho AL. (2013) Regulation of synapse composition by protein acetylation: the role of acetylated cortactin. J Cell Sci., 126:149-162. IF: 5.877, Q1

Correia SC, Carvalho C, Cardoso S, Santos RX, Plácido AI, Candeias E, Duarte AI, Moreira PI. (2013) Defective HIF signaling pathway and brain response to hypoxia in neurodegenerative diseases: not an "iffy" question! Curr. Pharm. Des. 19(38):6809-22. IF: 3.311, Q1

Correia SC, Perry G, Castellani R, Moreira PI. (2013) Is exercise-in-a-bottle likely to proffer new insights into Alzheimer´s disease? J. Neurochem. 127(1):4-6. IF: 3.973, Q2

Correia SC, Santos RX, Santos MS, Casadesus G, Lamanna JC, Perry G, Smith MA, Moreira PI. (2013) Mitochondrial abnormalities in a streptozotocin-induced rat model of sporadic Alzheimer´s disease. Curr. Alzheimer Res. 10(4):406-19. IF: 3.676, Q1

Costa RO, Ferreiro E, Oliveira CR, Pereira CM. (2013) Inhibition of mitochondrial cytochrome c oxidase potentiates Aβ-induced ER stress and cell death in cortical neurons. Mol Cell Neurosci. 52, 1-8. IF: 3.837, Q2

Costa RO, Ferreiro E, Oliveira CR, Pereira CF. (2013) Inhibition of mitochondrial cytochrome c oxidase potentiates Aβ-induced ER stress and cell death in cortical neurons. Mol. Cell. Neurosci. 52, 1-8. IF: 3.837, Q2

Cunha-Oliveira T, Rego AC, Oliveira CR. (2013) Oxidative stress and drugs of abuse: an update. Mini Rev. Org. Chem. 10, 321-334. Review, IF: 1.063, Q3

Duarte AI, Candeias E, Correia SC, Santos RX, Carvalho C, Cardoso S, Plácido A, Santos MS, Oliveira CR, Moreira PI. (2013) Crosstalk between diabetes and brain: glucagon-like peptide-1 mimetics as a promising therapy against neurodegeneration. Biochim. Biophys Acta. 1832(4):527-41. IF: 4.91, Q1

Espinosa J, Rocha A, Nunes F, Costa MS, Schein V, Kazlauckas V, Kalinine E, Souza DO, Cunha RA, Porciúncula LO. (2013) Caffeine consumption prevents memory impairment, neuronal damage and adenosine A2a receptors up-regulation in the hippocampus of a rat model of sporadic dementia. J. Alzheimer Dis. 34, 509-518. IF: 4.174, Q1

Fonseca AC, Ferreiro E, Oliveira CR, Cardoso SM, Pereira CF. (2013) Activation of the endoplasmic reticulum stress response by the amyloid-beta 1-40 peptide in brain endothelial cells. Biochim Biophys Acta. 1832, 2191-2203. IF: 4.910, Q1

Garção P, Szabó EC, Wopereis S, Castro AA, Tomé AR, Prediger RD, Cunha RA, Agostinho P, Köfalvi A. (2013) Functional interaction between presynaptic α6β2-containing nicotinic and adenosine A2A receptors in the control of dopamine release in the rat striatum. Br. J .Pharmacol. 169, 1600-1611. IF: 5.067, Q1

Gomes CA, Ferreira R, George J, Sanches R, Rodrigues DI, Gonçalves N, Cunha RA. (2013) Activation of microglial cells triggers a release of brain-derived neurotrophic factor (BDNF) inducing their proliferation in an adenosine A2A receptor-dependent manner. J. Neuroinflamm. 10, 16. IF: 4.351, Q1

Gonçalves N, Simões AT, Cunha RA, Pereira de Almeida L. (2013) Caffeine and adenosine A2A receptor inactivation decrease striatal neuropathology in a lentiviral-based model of Machado-Joseph disease. Ann. Neurol. 73, 655-666. IF: 11.193, Q1

González-Burgos E, Duarte AI, Carretero ME, Moreira PI, Gómez-Serranillos MP. (2013) Mitochondrial-targeted protective properties of isolated diterpenoids from sideritis spp. in response to the deleterious changes induced by H2O2. J. Nat. Prod. 76(5):933-8. IF: 3.285, Q1

Keri RS, Quintanova C, Marques SM, Esteves AR, Cardoso SM, Santos MA (2013) Design, synthesis and pharmacological evaluation of novel tacrine-benzothiazole hybrids as multi-targeted compounds against Alzheimer´s disease. Bioorganic and Medicinal Chemistry 21(15):4559-69. IF: 2.903, Q2

Köles L, Garção P, Zádori ZS, Ferreira SG, Pinheiro BS, da Silva-Santos CS, Ledent C, Köfalvi A. (2013) Presynaptic TRPV1 vanilloid receptor function is age- but not CB1 cannabinoid receptor-dependent in the rodent forebrain. Brain Res. Bull. 97, 126-135. IF: 2.935, Q2

Martins AD, Alves MG, Simões VL, Dias TR, Rato L, Moreira PI, Socorro S, Cavaco JE, Oliveira PF. (2013) Control of Sertoli cell metabolism by sex steroid hormones is mediated through modulation in glycolysis-related transporters and enzymes. Cell Tissue Res. 354(3):861-8. IF: 3.677, Q2

Martins I, Gomes S, Costa RO, Otvos L, Oliveira CR, Resende R, Pereira CM. (2013) Leptin and ghrelin prevent hippocampal dysfunction induced by Aβ oligomers. Neuroscience 241, 41-51. IF: 3.122, Q2

Matos M, Augusto E, Agostinho P, Cunha RA, Chen JF. (2013) Antagonistic interaction between adenosine A2A receptors and Na+/K+-ATPase-α2 controlling glutamate uptake in astrocytes. J. Neurosci. 33, 18492-18502. IF: 6.908, Q1

Melo CV, Okumoto S, Gomes JR, Baptista MS, Bahr BA, Frommer WB, Duarte CB. (2013) Spatiotemporal resolution of BDNF neuroprotection against glutamate excitotoxicity in cultured hippocampal neurons. Neurosci. 237, 66-86. IF: 3.122, Q2

Melo CV, Mele M, Curcio M, Comprido D, Silva CG, Duarte CB. (2013) BDNF regulates the expression and distribution of vesicular glutamate transporters in cultured hippocampal neurons. PLoS One 8, e53793. IF: 3.730, Q1

Mondragón-Rodríguez S, Perry G, Zhu X, Moreira PI, Acevedo-Aquino MC, Williams S. (2013) Phosphorylation of tau protein as the link between oxidative stress, mitochondrial dysfunction, and connectivity failure: implications for Alzheimer´s disease. Oxid. Med. Cell Longev. 2013:940603. IF: 3.393, Q2

Moreira PI. (2013) High-sugar diets, type 2 diabetes and Alzheimer´s disease. Curr. Opin. Clin. Nutr. Metab. Care. 16(4):440-5. IF: 4.519, Q1

Moreno AJ, Moreira PI, Custódio JB, Santos MS. (2013) Mechanism of inhibition of mitochondrial ATP synthase by 17β-estradiol. J. Bioenerg. Biomembr. 45(3):261-70. IF: 1.604, Q4

Morte MI, Carreira BP, Falcão MJ, Ambrósio AF, Soares-da-Silva P,  Araújo I M and Carvalho CM. (2013). Evaluation of neurotoxic and neuroprotective pathways affected by antiepileptic drugs in cultured hippocampal neurons. Toxicology in Vitro 27: 2193-2202 IF: 2.65

Morte MI, Carreira BP, Machado V, Carmo A, Nunes-Correia I. Carvalho CM and Araújo IM. (2013) Evaluation of proliferation of neural stem cells in vitro and in vivo. Curr. Protoc. Stem Cell Biol. 24:2D.14.1–2D.14.24.

Nunes A, Marques SM, Silva DF, Cardoso SM, Chaves S, Santos MA (2013) Multifunctional iron-chelators with protective roles against neurodegenerative diseases. Dalton Transactions 42(17):6058-73. IF: 3.806, Q1

Pandolfo P, Machado NJ, Köfalvi A, Takahashi RN, Cunha RA. (2013) Caffeine regulates frontocorticostriatal dopamine transporter density and improves attention and cognitive deficits in an animal model of attention deficit hyperactivity disorder. Eur. Neuropsychopharmacol. 23, 317-328. IF: 4.595, Q1

Pereira CMF. (2013) Crosstalk between endoplasmic reticulum stress and protein misfolding in neurodegenerative diseases. ISRN Cell Biol.  256404 (review- open access journal)

Perry EA, Castellani RJ, Moreira PI, Nunomura A, Lui Q, Harris PL, Sayre LM, Szweda PA, Szweda LI, Zhu X, Smith MA, Perry G. (2013) Neurofilaments are the major neuronal target of hydroxynonenal-mediated protein cross-links. Free Radic. Res. 47(6-7):507-10. IF: 3.279, Q2

Resende R, Marques SCF, Ferreiro E, Simões I, Oliveira CR, Pereira CMF. (2013) Effect of α-Synuclein on Amyloid β-Induced Toxicity: Relevance to Lewy Body Variant of Alzheimer Disease. Neurochem Res. 38, 797-806. IF: 2.125, Q3

Ribeiro M, Silva AC, Rodrigues J, Naia L, Rego AC. (2013) Oxidizing effects of exogenous stressors in Huntington´s disease knock-in striatal cells – protective effect of cystamine and creatine. Toxicol. Sci. 136, 487-499. IF: 4.328, Q1

Santana MM, Ehrhart-Bornstein M, Cavadas C. (2013) Progenitor cells in chromospheres: in response to Arthur S. Tischler. Stem Cells Transl. Med. 2(12):1020-1.

Santos-Carvalho A, Aveleira CA, Elvas F, Ambrósio AF, Cavadas C. (2013) Neuropeptide Y Receptors Y1 and Y2 are Present in Neurons and Glial Cells in Rat Retinal Cells in Culture. Invest. Ophthalmol. Vis. Sci. 54(1):429-43. IF: 3.6, Q1

Santos-Carvalho A, Álvaro AR, Ambrósio AF, Cavadas C. (2013) Neuropeptide Y receptors activation protects rat retinal neural cells against necrotic and apoptotic cell death induced by glutamate. Cell Death and Disease  4, e636. IF:6.044, Q1

Santos RX, Correia SC, Zhu X, Smith MA, Moreira PI, Castellani RJ, Nunomura A, Perry G. (2013) Mitochondrial DNA oxidative damage and repair in aging and Alzheimer´s disease. Antioxid. Redox Signal. 18(18):2444-57. doi: 10.1089/ars.2012.5039. Review, IF: 7.189, Q1

Shen HY, Canas PM, Garcia-Sanz P, Lan JQ, Boison D, Moratalla R, Cunha RA, Chen JF. (2013) Adenosine A2A receptors in striatal glutamatergic terminals and GABAergic neurons oppositely modulate psychostimulant action and DARPP-32 phosphorylation. PLoS One 8: e80902. IF: 3.73, Q1

Silva A, Almeida S, Laço M, Duarte AI, Domingues J, Oliveira CR, Januário C, Rego AC. (2013) Mitochondrial respiratory chain complex activity and bioenergetic alterations in human platelets derived from pre-symptomatic and symptomatic Huntington´s disease carriers. Mitochondrion 13, 801-809. IF: 4.025, Q2

Silva CG, Métin C, Fazeli W, Machado NJ, Darmopil S, Launay PS, Ghestem A, Nesa MP, Bassot E, Szabó E, Baqi Y, Müller CE, Tomé AR, Ivanov A, Isbrandt D, Zilberter Y, Cunha RA, Esclapez M, Bernard C. (2013) Adenosine receptor antagonists including caffeine alter fetal brain development in mice. Science Transl. Med. 5: 59-70. IF: 10.757, Q1

Silva DF, Selfridge JE, Lu J, E L, Cardoso SM, Swerdlow RH. (2013) Mitochondrial biogenesis an adaptive response to mitochondria dysfunction in MCI and AD cybrids. Human Molecular Genetics 22(19):3931-46. IF: 7.692, Q1

Silva DFF, Santana I, Esteves AR, Baldeiras I, Arduino DM, Oliveira CR, Cardoso SM. (2013) Prodromal metabolic phenotype in MCI cybrids: implications for Alzheimer´s disease. Current Alzheimer Research 10(2):180-90. IF: 3.676, Q1

Soares E, Prediger RD, Nunes S, Castro AA, Viana SD, Lemos C, Souza CM, Agostinho PM, Cunha RA, Carvalho E, Ribeiro CAF, Reis F, Pereira FC. (2013) Spatial memory impairments in a prediabetic rat model. Neuroscience 250, 565-577. IF: 3.122, Q2

Vindeirinho J, Costa GN, Correia MB, Cavadas C, Santos PF. (20139 Effect of diabetes/hyperglycemia on the rat retinal adenosinergic system. PLoS One 8(6):e67499. IF: 3.730, Q1
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