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Publicações 2020

Protein tyrosine phosphatase 1B inhibition as a potential therapeutic target for chronic wounds in diabetes.
Figueiredo A, et al, Pharmacol Res. 2020 Sep

A new tetra-plex fluorimetric assay for the quantification of cerebrospinal fluid β-amyloid42, total-tau, phospho-tau and α-synuclein in the differential diagnosis of neurodegenerative dementia.
Diaz-Lucena D, et al, J Neurol. 2020 Sep

Activated double-negative T cells (CD3+CD4-CD8-HLA-DR+) define response to renal denervation for resistant hypertension.
Delgado Silva J, et al, Clin Immunol. 2020 Sep

Genetic variation in APOE, GRN, and TP53 are phenotype modifiers in frontotemporal dementia.
Rosas I, et al, Neurobiol Aging. 2020 Sep 2

Lauroylated Histidine-Enriched S413-PV Peptide as an Efficient Gene Silencing Mediator in Cancer Cells.
Morais CM, et al, Pharm Res. 2020 Sep 4

P-cadherin induces anoikis-resistance of matrix-detached breast cancer cells by promoting pentose phosphate pathway and decreasing oxidative stress.
Sousa B, et al, Biochim Biophys Acta Mol Basis Dis. 2020 Sep 10

NLRP3 Inflammasome and Allergic Contact Dermatitis: A Connection to Demystify.
Sebastião AI, et al, Pharmaceutics. 2020 Sep 11

Alzheimer´s disease: Recent treatment strategies.
Vaz M, et al, Eur J Pharmacol. 2020 Sep 15

Permeability of the blood-brain barrier through the phases of ischaemic stroke and relation with clinical outcome: protocol for a systematic review.
Bernardo-Castro S, et al, BMJ Open. 2020 Sep 18

Phlorotannins from Fucus vesiculosus: Modulation of Inflammatory Response by Blocking NF-κB Signaling Pathway.
Catarino MD, et al, Int J Mol Sci. 2020 Sep 20

Role of Neuropeptide S on behavioural and neurochemical changes of an animal model of attention-deficit/hyperactivity disorder.
de Santana Souza L, et al, Neuroscience. 2020 Sep 22

Bacterial vaginosis: Standard treatments and alternative strategies.
Tomás M, et al, Int J Pharm. 2020 Sep 25

Biomimeting ultra-small lipid nanoconstructs for glioblastoma treatment: A computationally guided experimental approach.
Mendes M, et al, Int J Pharm. 2020 Sep 25

Fluorescent probes for the detection of reactive oxygen species in human spermatozoa.
Escada-Rebelo S, et al, Asian J Androl. 2020 Sep-Oct

Aging-related mitochondrial alterations in bovine oocytes.
Soares M, Sousa AP, et al, Theriogenology. 2020 Aug

Differential protein expression in diverse brain areas of Parkinson´s and Alzheimer´s disease patients.
Esteves AR, et al, 2020 Aug 4

Malespecific features are reduced in Mecp2null mice: analyses of vasopressinergic innervation, pheromone production and social behaviour
MartínezRodríguez E, et al, Brain Structure and Function August 4, 2020

Environmental Impact on Male (In)Fertility via Epigenetic Route.
Cescon M, et al, J Clin Med. 2020 Aug 5

Editorial: Interplay Between Nutrition, the Intestinal Microbiota and the Immune System.
Oriá RB, et al, Front Immunol. 2020 Aug 6

Neuronal adenosine A2A receptors signal ergogenic effects of caffeine.
Aguiar AS Jr, et al, Sci Rep. 2020 Aug 7

ATP Signaling Controlling Dyskinesia Through P2X7 Receptors.
Fonteles AA, et al, Front Mol Neurosci. 2020 Aug 7

Prolonged caffeine intake decreases alveolar bone damage induced by binge-like ethanol consumption in adolescent female rats.
Maia C, et al, Biomed Pharmacother. 2020 Aug 8

Isolation and Culture of Chick Ciliary Ganglion Neurons.
Costa FJ, et al, J Vis Exp. 2020 Aug 8

Lysosomal Storage Disease-Associated Neuropathy: Targeting Stable Nucleic Acid Lipid Particle (SNALP)-Formulated siRNAs to the Brain as a Therapeutic Approach.
Coutinho MF, et al, Int J Mol Sci. 2020 Aug 10

Maternal obesity in sheep impairs fetal hepatic respiratory chain capacity.
Serafim TL, et al, Eur J Clin Invest. 2020 Aug 11

Face-Specific Perceptual Distortions Reveal A View- and Orientation-Independent Face Template.
Almeida J, Freixo A, et al, Curr Biol. 2020 Aug 11

An optimized spectrophotometric assay reveals increased activity of enzymes involved in 2-arachidonoyl glycerol turnover in the cerebral cortex of a rat model of Alzheimer´s disease.
Rodrigues MS, et al, Eur J Neurosci. 2020 Aug 19

Associations between Trace Elements and Cognitive Decline: An Exploratory 5-Year Follow-Up Study of an Elderly Cohort.
Gerardo B, et al, Int J Environ Res Public Health. 2020 Aug 20

Decidual NK Cells Transfer Granulysin to Selectively Kill Bacteria in Trophoblasts.
Crespo ÂC, et al, Cell. 2020 August 20

Peptide-lipid nanoconstructs act site-specifically towards glioblastoma growth impairment.
Basso J, et al, Eur J Pharm Biopharm. 2020 Aug 20

Understanding the Binding Specificity of G-Protein Coupled Receptors toward G-Proteins and Arrestins: Application to the Dopamine Receptor Family.
Preto AJ, et al, J Chem Inf Model. 2020 Aug 24

Advances and challenges in retinoid delivery systems in regenerative and therapeutic medicine.
Ferreira R, et al, Nat Commun. 2020 Aug 26

Rheology by Design: A Regulatory Tutorial for Analytical Method Validation.
Simões A, et al, Pharmaceutics. 2020 Aug 28

Recurrent vulvovaginal Candida spp isolates phenotypically express less virulence traits.
Faria-Gonçalves P, et al, Microb Pathog. 2020 Aug 29

The blood-brain barrier is disrupted in Machado-Joseph disease/spinocerebellar ataxia type 3: evidence from transgenic mice and human post-mortem samples.
Duarte Lobo D, et al, Acta Neuropathol Commun. 2020 Aug 31

Activated double-negative T cells (CD3+CD4-CD8-HLA-DR+) define response to renal denervation for resistant hypertension.
Delgado Silva J, et al,  Clin Immunol. 2020 Jun 30

Caffeine Consumption plus Physical Exercise Improves Behavioral Impairments and Stimulates Neuroplasticity in Spontaneously Hypertensive Rats (SHR): an Animal Model of Attention Deficit Hyperactivity Disorder.
França AP, et al, Mol Neurobiol. 2020 Jul 3.

Progressing Towards the Sustainable Development of Cream Formulations.
Simões A, et al, Pharmaceutics. 2020 Jul 9

Semen supports growth of Candida albicans: A putative risk factor for recurrence of vulvovaginal infections?
Rolo J, et al, J Obstet Gynaecol Res. 2020 Jul 12

Biomimeting ultra-small lipid nanoconstructs for glioblastoma treatment: A computationally guided experimental approach.
Mendes M, et al, Int J Pharm. 2020 Jul 18

Estrogens decrease osteoclast number by attenuating mitochondria oxidative phosphorylation and ATP production in early osteoclast precursors.
Kim HN, et al,  Sci Rep. 2020 Jul 20

Insights from qualitative research on NAFLD awareness with a cohort of T2DM patients: time to go public with insulin resistance?
Alemany-Pagès M, et al,  BMC Public Health. 2020 Jul 20

Intra-dimer cooperativity between the active site cysteines during the oxidation of peroxiredoxin 2.
Peskin AV, et al,  Free Radic Biol Med. 2020 Jul 20

Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing.
Cunnane SC, et al,  Nat Rev Drug Discov. 2020 Jul 24

The Potential of Metabolomics in the Diagnosis of Thyroid Cancer.
Coelho M, et al,  Int J Mol Sci. 2020 Jul 24

The Secret Lives of Fluorescent Membrane Probes as Revealed by Molecular Dynamics Simulations.
Filipe HAL, et al 2020 Jul 28

Neuroprotective effects of melatonin against neurotoxicity induced by intranasal sodium dimethyldithiocarbamate administration in mice.
Mack JM, et al, Neurotoxicology 2020 Jul 29

Cofilin-1 Is a Mechanosensitive Regulator of Transcription
Domingues C, et al, Front Cell Dev Biol. 2020 July 30

Dihydroorotate Dehydrogenase Inhibitors in SARS-CoV-2 Infection.
Coelho AR, et al, Eur J Clin Invest. 2020 Jul 31

Neuropeptide Y Enhances Progerin Clearance and Ameliorates the Senescent Phenotype of Human Hutchinson-Gilford Progeria Syndrome Cells.
Aveleira CA, et al, J Gerontol A Biol Sci Med Sci. 2020 May 22

Sphaerococcus coronopifolius bromoterpenes as potential cancer stem cell-targeting agents.
Alves C, et al, Biomed Pharmacother. Epub 2020 May 30.

Lipid-core nanocapsules containing simvastatin improve the cognitive impairment induced by obesity and hypercholesterolemia in adult rats.
Lorenzoni R, et al, Eur J Pharm Sci. 2020 May 30.

Correction to: In vitro mechanistic studies on α-amanitin and its putative antidotes.
Rodrigues DF, et al, Arch Toxicol. 2020 Jun.

Microbiology Editor´s Choice: understanding a mycobacterial thermophile
Microbiology Society, 2020 Jun 1.  

Native and bioengineered extracellular vesicles for cardiovascular therapeutics.
de Abreu RC, et al, Nat Rev Cardiol. 2020 Jun 1.

Role of Adenosine in Epilepsy and Seizures.
Tescarollo FC, et al, J Caffeine Adenosine Res. 2020 Jun 1.

Preclinical efficacy of gemcitabine in MLL-rearranged infant acute lymphoblastic leukemia.
Wander P, et al, Leukemia. 2020 Jun 2.

Social subordination induced by early life adversity rewires inhibitory control of the prefrontal cortex via enhanced Npy1r signaling.
Franco LO, et al, Neuropsychopharmacology. 2020 Jun 3.

Protein tyrosine phosphatase 1B inhibition as a potential therapeutic target for chronic wounds in diabetes.
Figueiredo A, et al, Pharmacol Res. 2020 Jun 3.

Chemical characterization and bioactivity of the essential oil from Santolina insularis, a Sardinian endemism.
Alves-Silva JM, et al, Nat Prod Res. 2020 Jun 4.

Mitochondrial and Redox-Based Therapeutic Strategies in Huntington´s Disease.
Fão L, et al, Antioxid Redox Signal. 2020 Jun 4.

QbD-driven development of intranasal lipid nanoparticles for depression treatment.
Vitorino C, et al, Eur J Pharm Biopharm. 2020 Jun 7.

Enzymatic Synthesis of Polyesters: a QM/MM study.
Pedro Figueiredo et al, ChemCatChem, 2020 June 12. 

Che-1/AATF binds to RNA polymerase I machinery and sustains ribosomal RNA gene transcription.
Sorino C, et al, Nucleic Acids Res. 2020 Jun 19.

New BACE1 Chimeric Peptide Inhibitors Selectively Prevent AβPPβ Cleavage Decreasing Amyloid-β Production and Accumulation in Alzheimer´s Disease Models.
Resende R, et al, J Alzheimers Dis. 2020 Jun 22.

Intermediary metabolism: An intricate network at the crossroads of cell fate and function.
Ferreira LMR, et al, Biochim Biophys Acta Mol Basis Dis. 2020 Jun 26.

The mTOR pathway in reproduction: from gonadal function to developmental coordination.
Correia B, et al, Reproduction. Review 2020 Apr

Chronic hyperglycemia impairs hippocampal neurogenesis and memory in an Alzheimer´s disease mouse model.
Ferreiro E, et al, Neurobiol Aging. 2020 Apr 15

Diabetes-Alzheimer´s Disease Link: Targeting Mitochondrial Dysfunction and Redox Imbalance.
Carvalho C, et al, Antioxid Redox Signal. 2020 Apr 20

Airborne route and bad use of ventilation systems as non-negligible factors in SARS-CoV-2 transmission.
Correia G, et al, Med Hypotheses. 2020 Apr 25

Analytical methods to monitor dopamine metabolism in plasma: Moving forward with improved diagnosis and treatment of neurological disorders.
Abrantes Dias AS, et al, J Pharm Biomed Anal. 2020 Apr 28

Donepezil-based hybrids as multifunctional anti-Alzheimer´s disease chelating agents: Effect of positional isomerization.
Costa M, et al, J Inorg Biochem. 2020 May  

Stabilization of blood for long-term storage can affect antibody-based recognition of cell surface markers.
Silva MH, et al, J Immunol Methods. 2020 May

Drp1-mediated mitochondrial fission regulates calcium and F-actin dynamics during wound healing.
Ponte S, et al, Biol Open. 2020 May 3

A new tetra-plex fluorimetric assay for the quantification of cerebrospinal fluid β-amyloid42, total-tau, phospho-tau and α-synuclein in the differential diagnosis of neurodegenerative dementia.
Diaz-Lucena D, et al, J Neurol. 2020 May 5

Current Genetic Engineering Strategies for the Production of Anti-Hypertensive Acei Peptides.
Gomes C, et al, Biotechnol Bioeng. Review, 2020 May 5

Lack of lymphocytes impairs macrophage polarization and angiogenesis in diabetic wound healing.
Seraphim PM, et al, Life Sci. 2020 May 16

Transient Gain of Function of Cannabinoid CB1 Receptors in the Control of Frontocortical Glucose Consumption in a Rat Model of Type-1 Diabetes.
Pedro JR, et al, Brain Res Bull. 2020 May 16

Che-1/AATF binds to RNA polymerase I machinery and sustains ribosomal RNA gene transcription.
Sorino C, et al, Nucleic Acids Res. 2020 May 18

Pollen Proteases Play Multiple Roles in Allergic Disorders.
Gaspar R, et al, Int J Mol Sci. 2020 May 19

A genuine mycobacterial thermophile: Mycobacterium hassiacum growth, survival and GpgS stability at near-pasteurization temperatures.
Alarico S, et al, Microbiology. 2020 May [EDITOR´S CHOICE]

Proteomics-based Predictive Model for the Early Detection of Metastasis and Recurrence in Head and Neck Cancer.
Ribeiro IP, et al, Cancer Genomics Proteomics. 2020 May-Jun

Microbial BMAA and the Pathway for Parkinson´s Disease Neurodegeneration.
Nunes-Costa D, et al, Front Aging Neurosci. 2020 Feb

The belated US FDA approval of the adenosine A2A receptor antagonist istradefylline for treatment of Parkinson´s disease.
Chen JF, et al, Purinergic Signal. 2020 Mar

Nanomedicines for the Delivery of Antimicrobial Peptides (AMPs).
Teixeira MC, et al,  Nanomaterials (Basel). 2020 Mar

Acrocomia aculeata (Jacq.) Lodd. ex Mart. Leaves Increase SIRT1 Levels and Improve Stress Resistance.
Monteiro-Alfredo T, et al, Oxid Med Cell Longev. 2020 Mar

Limitations to Starch Utilization in Barramundi (Lates calcarifer) as Revealed by NMR-Based Metabolomics.
Palma M, et al, Front Physiol. 2020 Mar

Mitochondrial impairment and cytotoxicity effects induced by the marine epibenthic dinoflagellate Coolia malayensis.
Varela AT, et al, Environ Toxicol Pharmacol. 2020 Mar

Combining Virtual Screening Protocol and In Vitro Evaluation towards the Discovery of BACE1 Inhibitors.
Coimbra JRM, et al, Biomolecules. 2020 Apr

Secondary metabolites (essential oils) from sand-dune plants induce cytotoxic effects in cancer cells.
Beeby E, et al, J Ethnopharmacol. 2020 Apr

Metabolic characterization of a paused-like pluripotent state.
Sousa MI, et al, Biochim Biophys Acta Gen Subj. 2020 Apr

Trehalose alleviates the phenotype of Machado-Joseph disease mouse models.
Santana MM, et al, J Transl Med. 2020 Apr

Characterization of sheep erythrocyte glycosphingolipids recognized by human anti-Forssman antibodies.
Santos L, et al, Glycobiology. 2020 Apr

Publicly Stressing the Role of Mitochondria in NAFLD with(in) a Sports Event.
Alemany-Pagès M, et al, Eur J Clin Invest. 2020 Apr

Correction to: In vitro mechanistic studies on α-amanitin and its putative antidotes.
Rodrigues DF, et al, Arch Toxicol. 2020 Apr

High sensitivity of rat cardiomyoblast H9c2(2-1) cells to Gambierdiscus toxic compounds.
Neves RAF, et al, Aquat Toxicol. 2020 Apr

Calcium Phosphate Ceramics Can Prevent Bisphosphonate-Related Osteonecrosis of the Jaw.
Paulo S, et al, Materials (Basel). 2020 Apr

Using the quality by design (QbD) approach to optimize formulations of lipid nanoparticles and nanoemulsions: A review.
Cunha S, et al, Nanomedicine. 2020 Apr

Neuronal pentraxin 2: a synapse-derived CSF biomarker in genetic frontotemporal dementia.
van der Ende EL, et al, J Neurol Neurosurg Psychiatry. 2020 Apr

The cholesterol 24-hydroxylase activates autophagy and decreases mutant huntingtin build-up in a neuroblastoma culture model of Huntington´s disease.
Nóbrega C, et al, BMC Res Notes. 2020 Apr

Expression and function of the nonclassical estrogen receptor, GPR30, in human cartilage and chondrocytes.
Ribeiro M, et al, J Cell Physiol. 2020 Apr

Correction to: Prevalence of vitamin D deficiency and its predictors in the Portuguese population: a nationwide population-based study.
Duarte C, et al, Arch Osteoporos. 2020 Apr

A different vision of translational research in biomarker discovery: a pilot study on circulatory mitochondrial proteins as Parkinson´s disease potential biomarkers.
Anjo SI, et al, Transl Neurodegener. 2020 Apr

Giardia lamblia Decreases NF-κB p65RelA Protein Levels and Modulates LPS-Induced Pro-Inflammatory Response in Macrophages.
Faria CP, et al, Sci Rep. 2020 Apr

Tolerance to arsenic contaminant among multidrug-resistant and copper-tolerant Salmonella successful clones is associated with diverse ars operons and genetic contexts.
Mourão J, et al, Environ Microbiol. 2020 Apr

Glioblastoma hijacks microglial gene expression to support tumor growth.
Maas SLN, et al, J Neuroinflammation. 2020 Apr

A Methodological Safe-by-Design Approach for the Development of Nanomedicines.
Schmutz M, et al, Front Bioeng Biotechnol. 2020 Apr

Estimating pentose phosphate pathway activity from the analysis of hepatic glycogen 13 C-isotopomers derived from [U-13 C]fructose and [U-13 C]glucose.
Belew GD, et al, Magn Reson Med. 2020 Apr

Neonatal diet impacts liver mitochondrial bioenergetics in piglets fed formula or human milk.
Carvalho E, et al, BMC Nutr. 2020 Apr

Urine-Derived Stem Cells: Applications in Regenerative and Predictive Medicine.
Bento G, et al, Cells. 2020 Feb

From Xanthine Oxidase Inhibition to In Vivo Hypouricemic Effect: An Integrated Overview of In Vitro and In Vivo Studies with Focus on Natural Molecules and Analogues.
Serrano JL, et al, Evid Based Complement Alternat Med. 2020 Feb

Morphometry and gyrification in bipolar disorder and schizophrenia: A comparative MRI study.
Madeira N, et al, Neuroimage Clin. 2020 Feb

Memory and Cognition-Related Neuroplasticity Enhancement by Transcranial Direct Current Stimulation in Rodents: A Systematic Review.
Cavaleiro C, et al, Neural Plast. 2020 Feb

Assessment of Susceptibility to Five Common Antibiotics and Their Resistance Pattern in Clinical Enterococcus Isolates.
Masoumi Zavaryani S, et al, Epub 2020 Feb

Liraglutide Protects Against Brain Amyloid-β1-42 Accumulation in Female Mice with Early Alzheimer´s Disease-Like Pathology by Partially Rescuing Oxidative/Nitrosative Stress and Inflammation.
Duarte AI, et al, nt J Mol Sci. 2020 Mar

Donepezil-based hybrids as multifunctional anti-Alzheimer´s disease chelating agents: Effect of positional isomerization.
Costa M, et al, Epub 2020 Feb

Chitosan Nanoparticles: Shedding Light on Immunotoxicity and Hemocompatibility.
Jesus S, et al, Front Bioeng Biotechnol. 2020 Feb

Dipeptidyl peptidase-4 inhibitors and sulfonylureas prevent the progressive impairment of the nigrostriatal dopaminergic system induced by diabetes during aging.
Lietzau G, et al, 10.1016/j.neurobiolaging.2020.01.004. Epub 2020 Feb

Stem metabolism: Insights from oncometabolism and vice versa.
Rodrigues AS, et al, Biochim Biophys Acta Mol Basis Dis. 2020 Mar

Characterization and Cytotoxicity Assessment of the Lipophilic Fractions of Different Morphological Parts of Acacia dealbata.
Oliveira CSD, et al, Int J Mol Sci. 2020 Mar

In memoriam - Milton Simões da Costa (1948-2020).
Albuquerque L, et al, Int J Syst Evol Microbiol. 2020 Mar

Response of the cerebral vasculature to systemic carbon monoxide administration - regional differences and sexual dimorphism.
Oliveira SR, et al, Eur J Neurosci. 2020 Mar

Obtaining Cancer Stem Cell Spheres from Gynecological and Breast Cancer Tumors.
Laranjo M, et al, J Vis Exp. 2020 Mar

Drp1-mediated mitochondrial fission regulates calcium and F-actin dynamics during wound healing.
Ponte S, et al, Biol Open. 2020 Mar

Dietary starch promotes hepatic lipogenesis in barramundi (Lates calcarifer).
Wade NM, et al, Br J Nutr. 2020 Mar

In vitro mechanistic studies on α-amanitin and its putative antidotes.
Rodrigues DF, et al, Arch Toxicol. 2020 Mar

Screening-level evaluation of marine benthic dinoflagellates toxicity using mammalian cell lines.
Neves RAF, et al, Ecotoxicol Environ Saf. 2020 Mar

Protocol for the Characterization of the CAG Tract and Flanking Polymorphisms in Machado-Joseph Disease: Impact on Diagnosis and Development of Gene-Based Therapies.
Lopes SM, et al, J Mol Diagn. 2020 Mar

Mitochondrial Determinants of Doxorubicin-Induced Cardiomyopathy.
Wallace KB, et al,  Epub 2020 Mar

Hypoxia and Macrophages Act in Concert Towards a Beneficial Outcome in Colon Cancer.
Martins F, et al, Cancers (Basel). 2020 Ma

The T-box transcription factor brachyury behaves as a tumor suppressor in gliomas.
Pinto F, et al, J Pathol. 2020 Mar

The Mitochondrial Ribosome: A World of Opportunities for Mitochondrial Dysfunction Toward Parkinson´s Disease.
Gonçalves AM, et al, Antioxid Redox Signal. 2020 Mar

Comparative genome sequence analysis of several species in the genus Tepidimonas and the description of a novel species Tepidimonas charontis sp. nov.
Albuquerque L, et al, Int J Syst Evol Microbiol. 2020 Mar

Airborne environmental fine particles induce intense inflammatory response regardless of the absence of heavy metal elements.
Colaço M, et al, 10.1016/j.ecoenv.2020.110500. [Epub ahead of print]

How the Lack of Chitosan Characterization Precludes Implementation of the Safe-by-Design Concept.
Marques C, et al, Front Bioeng Biotechnol. 2020 Mar

The Peculiar Facets of Nitric Oxide as a Cellular Messenger: From Disease-Associated Signaling to the Regulation of Brain Bioenergetics and Neurovascular Coupling.
Laranjinha J, et al, Neurochem Res. 2020 Mar

Endophilin-A coordinates priming and fusion of neurosecretory vesicles via intersectin.
Gowrisankaran S, et al, Nat Commun. 2020 Mar

Safe-by-Design of Glucan Nanoparticles: Size Matters When Assessing the Immunotoxicity.
Colaço M, et al, Chem Res Toxicol. 2020 Mar

Prevalence of vitamin D deficiency and its predictors in the Portuguese population: a nationwide population-based study.
Duarte C, et al, Arch Osteoporos. 2020 Mar

miRNA-31 Improves Cognition and Abolishes Amyloid-β Pathology by Targeting APP and BACE1 in an Animal Model of Alzheimer´s Disease.
Barros-Viegas AT, et al, Mol Ther Nucleic Acids. 2020 Jan 17

The Impact Of Exercise On Inflammation, Oxidative Stress And Remodelling In Cardiac Muscle.
Mendes F, et al, Arq Bras Cardiol. 2020 Jan

Neuropeptide Y Enhances Progerin Clearance and Ameliorates the Senescent Phenotype of Human Hutchinson-Gilford Progeria Syndrome Cells.
Aveleira CA, et al, J Gerontol A Biol Sci Med Sci. 2020 Feb

Tumour functional imaging by PET.
Abrantes AM, et al, Biochim Biophys Acta Mol Basis Dis. 2020 Feb

Polyphenols in the management of brain disorders: Modulation of the microbiota-gut-brain axis.
Serra D, et al, Adv Food Nutr Res. 2020

Calcium Signaling in Aging and Neurodegenerative Diseases 2019.
Cortes L, et al, Int J Mol Sci. 2020 Feb

Timing in drug absorption and disposition: the past, present and future of chronopharmacokinetics.
Bicker J, et al, Br J Pharmacol. 2020 Feb

Dendritic Cell Vaccines for Cancer Immunotherapy: The Role of Human Conventional Type 1 Dendritic Cells.
Calmeiro J, et all, Pharmaceutics. 2020 Feb

A SOX2 Reporter System Identifies Gastric Cancer Stem-Like Cells Sensitive to Monensin.
Pádua D, et al, Cancers (Basel). 2020 Feb

Mechanical and Tribological Characterization of a Dental Ceromer.
Santos M, et al, J Funct Biomater. 2020 Feb

Design, Synthesis, and In Vitro Evaluation of Hydroxybenzimidazole-Donepezil Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer´s Disease.
Chaves S, et al, Molecules. 2020 Feb

The Central Role of Non-Structural Protein 1 (NS1) in Influenza Biology and Infection.
Rosário-Ferreira N, et al, Int J Mol Sci. 2020 Feb

THE MITORIBOSOME: A WORLD OF OPPORTUNITIES FOR MITOCHONDRIAL DYSFUNCTION TOWARD PARKINSON´S DISEASE.
Gonçalves AM, et al, Antioxid Redox Signal. 2020 Feb

A genuine mycobacterial thermophile: Mycobacterium hassiacum growth, survival and GpgS stability at near-pasteurization temperatures.
Alarico S, et al, Microbiology. 2020 Feb

Mitochondria, endoplasmic reticulum and innate immune dysfunction in mood disorders: Do mitochondria-associated membranes (MAMs) play a role?
Resende R, et al, Biochim Biophys Acta Mol Basis Dis. 2020 Feb

Neuropsychological Contribution to Predict Conversion to Dementia in Patients with Mild Cognitive Impairment Due to Alzheimer´s Disease.
Silva D, et al, J Alzheimers Dis. 2020 Feb

Identification of new targets of S-nitrosylation in neural stem cells by thiol redox proteomics.
Santos AI, et al, Redox Biol. 2020 Feb

Nitrate from diet might fuel gut microbiota metabolism: Minding the gap between redox signaling and inter-kingdom communication.
Rocha BS, et al, Free Radic Biol Med. 2020 Feb

Fragaria vesca L. Extract: A Promising Cosmetic Ingredient with Antioxidant Properties.
Couto J, et al, Antioxidants (Basel). 2020 Feb

Diabetes-Alzheimer´s disease link: Targeting mitochondrial dysfunction and redox imbalance.
Carvalho C, et al, Antioxid Redox Signal. 2020 Feb

Dendritic Cell Vaccines for Cancer Immunotherapy: The Role of Human Conventional Type 1 Dendritic Cells
Calmeiro J, et al,  Pharmaceutics (IF 4,773). 2020 Feb

Iodine131 metabolic radiotherapy leads to cell death and genomic alterations through NIS overexpression on cholangiocarcinoma.
Brito AF, et al, Int J Oncol. 2020 Jan

Highly Efficient Singlet Oxygen Generators Based on Ruthenium Phthalocyanines: Synthesis, Characterization and in vitro Evaluation for Photodynamic Therapy.
Ferreira JT, et al, Chemistry. 2020 Jan

The Role of Magnetic Nanoparticles in Cancer Nanotheranostics.
Ferreira M, et al, Materials (Basel). 2020 Jan

Fluorescent probes for the detection of reactive oxygen species in human spermatozoa.
Escada-Rebelo S, et al, Asian J Androl. 2020 Jan

Prediction and targeting of GPCR oligomer interfaces.
Barreto CAV,  et al, Prog Mol Biol Transl Sci. 2020

Characterization of a Parkinson´s disease rat model using an upgraded paraquat exposure paradigm.
Cristóvão AC, et al, Eur J Neurosci. 2020 Jan

SLMP53-1 Inhibits Tumor Cell Growth through Regulation of Glucose Metabolism and Angiogenesis in a P53-Dependent Manner.
Ramos H,  et al, Int J Mol Sci. 2020 Jan

Control of glutamate release by complexes of adenosine and cannabinoid receptors.
Köfalvi A,  et al, BMC Biol. 2020 Jan

Dual Imaging Gold Nanoplatforms for Targeted Radiotheranostics.
Silva F, et al, Materials (Basel). 2020 Jan

Specific Nutritional Biomarker Profiles in Mild Cognitive Impairment and Subjective Cognitive Decline Are Associated With Clinical Progression: The NUDAD Project.
de Leeuw FA, et al, J Am Med Dir Assoc. 2020 Jan

Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementia.
Llorens F, et al, Nat Commun. 2020 Jan

Evaluation of a novel dog animal model for peri-implant disease: clinical, radiographic, microbiological and histological assessment.
Martins O, et al, Clin Oral Investig. 2020 Jan

Heterogeneous EGFR, CDK4, MDM4, and PDGFRA Gene Expression Profiles in Primary GBM: No Association with Patient Survival.
González-Tablas M, et al, Cancers (Basel). 2020 Jan

Antibacterial Photodynamic Inactivation of Antibiotic-Resistant Bacteria and Biofilms with Nanomolar Photosensitizer Concentrations.
Vinagreiro CS, et al, ACS Infect Dis. 2020 Jan

Design of novel monoamine oxidase-B inhibitors based on piperine scaffold: Structure-activity-toxicity, drug-likeness and efflux transport studies.
Chavarria D, et al, Eur J Med Chem. 2020 Jan

Epicardial adipose tissue volume and annexin A2/fetuin-A signalling are linked to coronary calcification in advanced coronary artery disease: Computed tomography and proteomic biomarkers from the EPICHEART study.
Mancio J, et al, Atherosclerosis. 2020 Jan

The mTOR Pathway in Reproduction: From Gonadal Function to Developmental Coordination.
Correia B, et al, Atherosclerosis. 2020 Jan

Mitochondria-Lysosome Crosstalk: From Physiology to Neurodegeneration.
Deus CM, et al, Trends Mol Med. 2020 Jan

Continuous theta burst stimulation increases contralateral mu and beta rhythms with arm elevation: implications for neurorehabilitation.
Dionísio A, et al, J Neural Transm (Vienna). 2020 Jan

"The vaginal sheet: an innovative form of vaginal film for the treatment of vaginal infections".
Machado RSM, et al, Drug Dev Ind Pharm. 2020 Jan

p-Aminobenzoic acid as an alternative chemical biopsy agent for human hepatic UDP-glucose.
Barosa C, et al, Anal Biochem. 2020 Feb

 
   
Financiado por Fundos FEDER através do Programa Operacional Factores de Competitividade – COMPETE 2020 e por Fundos Nacionais através da FCT – Fundação para a Ciência e a Tecnologia no âmbito do projectos POCI-01-0145-FEDER-007440 e UIDB/04539/2020.

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