Biotecnologia e Saúde

Andrade, X., Botti, S., Marques, M.A.L., and Rubio, A. (2007). A time-dependent density functional theory scheme for efficient calculations of dynamic (hyper)polarizabilities. J. Chem. Phys. 126, 184106.

Bertin S, Neves S, Gavelli A, Baqué P, Brossete N, Rossi B, Simões S, Pedroso de Lima MC, Pierrefite-Carle V. (2007) Cellular and molecular events associated with the antitumor response induced by the cytosine deaminase/5-fluorocytosine suicide gene therapy system in a rat liver metastasis model. Can. Gene Ther. 14:858-866.

Bertin S, Neves S, Pedroso de Lima M, Pierrefite-Carle V. (2007) Naked DNA and lipoplexes applications in cancer gene therapy. Bull. Cancer 94:243-252.

Cardoso ALC, Simões S, Almeida LP, Pelisek J, Culmsee C, Wagner E, Pedroso de Lima MC. (2007) siRNA delivery by a transferrin-associated lipid-based vector: a non-viral strategy to mediate gene silencing. J. Gene Med. 9:170-183.

Duzgunes N, Simões S, Lopez-Mesas M, Pedroso de Lima MC. (2007) Intracellular delivery of therapeutic oligonucleotides in pH-sensitive and cationic liposomes. In: Liposome Technology Vol. 3, Chapter 14 (G. Gregoriadis Ed.), Marcel Dekker, Inc., New York, pp. 253-275.

Eulálio A, Nunes-Correia I, Salas J, Salas ML, Simões S, Pedroso de Lima MC. (2007) The structural protein p37 of African swine fever virus is localized in the nucleus at early times of viral infection. Vírus Res. 130:18-27.

Faneca H, Cabrita AS, Simões S, Pedroso de Lima MC. (2007) Evaluation of the antitumoral effect mediated by IL-12 and HSV-tk genes when delivered by a novel lipid-based system. Biochim. Biophys. Acta 1768:1093-1102.

Ferreira LS*, Zumbuehl A*, Kuhn D, Astashkina A, Long L, Yeo Y, Iaconis T, Ghannoum M, Fink GR, Langer R, Kohane DS. (2007) “Antifungal hydrogels”. Proceedings of the National Academy of Sciences, 104, 12994-12998. *Authors contributed equally.

Ferreira L, Gerecht-Nir S, Shieh HF, Watson N, Rupnick M, Dallabrida SM Vunjak-Novakovic G, Robert Langer R. (2007) “Vascular progenitor cells isolated from human embryonic stem cells give rise to endothelial and smooth muscle-like cells and form vascular networks in vivo”. Circulation Research, 101, 286-294.

Ferreira L, Gerecht S, Fuller J, Shieh HF, Vunjak-Novakovic G, Langer R. (2007) “Bioactive hydrogel scaffolds for controllable vascular differentiation of human embryonic stem cells”. Biomaterials, 28(17), 2706-2717.

Ferreira* L, Khademhosseini* A, Karp* JM, Gerecht-Nir* S, Vunjak-Novakovic G, Langer R. (2007) “Embryonic stem cells as a cell source for tissue engineering”. In: “Principles of Tissue Engineering- 3rd edition”. Editors: Lanza, R., Langer, R., Vacanti, J.P. Elsevier/Academic Press. (*Authors contributed equally).

Ferreira, P.G., Silva, C.G., Brito, R.M.M., and Azevedo, P.J. (2007). A closer look on protein unfolding simulations through hierarchical clustering. Proceedings of the 2007 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB07), pp. 461-468.

Gerecht-Nir S, Burdick JA, Ferreira LS, Langer R, Vunjak-Novakovic G. (2007) “Propagation of undifferentiated human embryonic stem cells in 3-dimentional hyaluronic acid networks”. Proceedings of the National Academy of Sciences, 104(27), 11298-11303.

Hansen D, Macedo-Ribeiro S, Veríssimo P, Yoo Im S, Sampaio UM, and Oliva ML. (2007) Crystal structure of a novel cysteinless plant kunitz-type protease inhibitor. Biochem. Biophys Res Commun. 360: 735-40.

Karp JM, Mahdavi A, Ferreira LS, Khademhosseini A, Langer R. (2007) “In vitro differentiation of human embryonic stem cells along osteogenic pathways”. In: “Human Embryonic Stem Cells: A Practical Handbook”, edited by: Sullivan S, Cowan C, Eggan K. John Wiley & Sons, Ltd.

Luo, Y, Ferreira, L, Langer R. (2007) “Three-dimensional scaffolds”. In: “Principles of Tissue Engineering- 3rd edition”. Editors: Lanza, R., Langer, R., Vacanti, J.P. Elsevier/Academic Press.

Macedo-Ribeiro S, Pereira de Almeida L, Carvalho A, Rego A (2007) Polyglutamine expansion diseases – the case of Machado-Joseph disease. In: Interactions Between Neurons and Glia in Aging and Disease (Malva J, Rego A, Oliveira C, Cunha R, eds): Springer.

Mano M, Henriques A, Paiva A, Prieto M, Gavilanes F, Simões S, Pedroso de Lima MC. (2007) Interaction of S413-PV cell penetrating peptide with model membranes: Relevance to peptide translocation across biological membranes. J. Peptide Sci.13:301-313.

Nijst C, Joost J, Karp JM, Ferreira L, Zumbuehl A, Bettinger C, Langer R. “Development of Multifunctional Photocurable Degradable Elastomers”. Biomacromolecules 2007, 8, 3067-3073.

Pimentel C, Van der Straeten D, Pires E, Faro C, and Rodrigues-Pousada C. (2007) Characterization and expression analysis of the aspartic protease family of Cynara cardunculus L. FEBS J. 274: 2523-39.

Simões I, Faro MR, Bur D, and Faro C. (2007) Characterization of recombinant CDR1, an Arabidopsis aspartic protease involved in disease resistance J. Biol. Chem. 282: 31358-65.