Toxicologia Celular e Molecular

Almeida B, Buttner S, Ohlmeier S, Silva A, Mesquita A, Sampaio-Marques B, Osorio NS, Kollau A, Mayer B, Leao C, Laranjinha J, Rodrigues F, Madeo F, Ludovico P. (2007) NO-mediated apoptosis in yeast. J. Cell. Sci. 120(Pt 18) 3279-3288.

Alves G, Figueiredo I, Castel-Branco M, Loureiro A, Fortuna A, Falcão AC, and Caramona MM. (2007) Enantioselective HPLC-UV method for eslicarbazepine acetate (BIA 2-093) and its metabolites determination in human plasma. Biomed. Chromatogr. 21(11): 1127-1134

Alves G, Figueiredo I, Castel-Branco M, Loureiro A, Falcão AC, and Caramona MM. (2007) Simultaneous and enantioselective liquid chromatographic determination of eslicarbazepine acetate, S-licarbazepine, R-licarbazepine and oxcarbazepine in mouse tissue samples using ultraviolet detection. Anal. Chim. Acta. 596(1): 132-140.

Ascensão A, Ferreira R, Oliveira PJ, Magalhães J. (2007) Effects of Endurance Training and Acute Doxorubicin Treatment on Rat Heart Mitochondrial Alterations Induced by in vitro Anoxia-reoxygenation, Cardiovasc. Toxicol. 6(3-4):159-72.

Correia HS, Batista MT, Dinis TCP. (2007) The activity of an extract and fraction of Agrimonia eupatoria L. against reactive species. Biofactors 29:91-104.

Falcão AC, Maia J, Almeida L, Mazur D, Gellert M, Soares-da-Silva P. (2007) Effect of gender on the pharmacokinetics of eslicarbazepine acetate (BIA 2-093), a new voltage-gated sodium channel blocker. Biopharm. Drug Dispos. 28:249-256.

Gago G, Lundberg JO, Barbosa RM, Laranjinha J. (2007) Red wine-dependent reduction of nitrite to nitric oxide in the stomach. Free Rad. Biol. Med. 43:1233-1242.

Laranjinha J, Ledo A. (2007) Coordination of physiologic and toxic pathways in hippocampus by nitric oxide and mitochondria. Frontiers in Bioscience, 12:1094-1106.

Magalhães J, Ferreira R, Neuparth MJ, Oliveira PJ, Marques F, Ascensão A. (2007) Vitamin E prevents hypobaric hypoxia-induced mitochondrial dysfunction in skeletal muscle. Clin Sci (Lond). Dec;113(12):459-66.

Moreira PI, Custódio JB, Nunes E, Moreno A, Seiça R, Oliveira CR, Santos MS (2007). Estradiol affects liver mitochondrial function in ovariectomized and tamoxifen-treated ovariectomized female rats. Toxicol Appl Pharmacol. 221(1):102-10.

Moreno AJ, Oliveira PJ, Nova CD, Alvaro AR, Moreira RA, Santos SM, Macedo T. (2007) Unaltered hepatic oxidative phosphorylation and mitochondrial permeability transition in Wistar rats treated with nimesulide: Relevance for nimesulide toxicity characterization. J Biochem Mol Toxicol.; 21(2):53-61.

Moreno AJ, Serafim TL, Oliveira PJ, Madeira VM. (2007) Inhibition of mitochondrial bioenergetics by carbaryl is only evident for higher concentrations -- Relevance for carbaryl toxicity mechanisms. Chemosphere;66(3):404-11.

Neves MAC, Dinis TCP, Colombo G, Sá e Melo, M.L. (2007). Combining computational and biochemical studies for a rationale on the anti-aromatase activity of natural polyphenols. Chem. Med. Chem. 2:1750-1762.

Nunes E, Peixoto F, Louro T, Sena CM, Santos MS, Matafome P, Moreira PI, Seiça R. (2007) Soybean oil treatment impairs glucose-stimulated insulin secretion and changes fatty acid composition of normal and diabetic islets. Acta Diabetol; 44:121-130.

Osório NS, Carvalho A, Almeida AJ, Padilla-Lopez S, Leao C, Laranjinha J, Ludovico P, Pearce DA, Rodrigues F. (2007) Nitric oxide signaling is disrupted in the yeast model for Batten disease. Mol. Biol. Cell. 18:2755-2767.

Palmeira CM, Rolo AP, Berthiaume J, Bjork JA, Wallace KB. Hyperglycemia decreases mitochondrial function: the regulatory role of mitochondrial biogenesis. Toxicol Appl Pharmacol. 225(2):214-20.

Pereira GC, Branco AF, Matos JA, Pereira SL, Parke D, Perkins EL, Serafim TL, Sardão VA, Santos MS, Moreno AJ, Holy J, Oliveira PJ. (2007) Mitochondrially targeted effects of berberine [Natural Yellow 18, 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a) quinolizinium] on K1735-M2 mouse melanoma cells: comparison with direct effects on isolated mitochondrial fractions. J Pharmacol Exp Ther.; 323(2):636-49.

Ribeiro L, Falcão AC, Patrício JAB, Ferreira DC, and Veiga FJB. (2007) Cyclodextrin multicomponent complexation and controlled release delivery strategies to optimise the oral bioavailability of vinpocetine. J. Pharmacol. Sci. 96(8): 2018-2028.

Rocha MJ, Almeida AM, Falcão AC, and Caramona MM. (2007) Performance of gentamicin population kinetic parameters in Portuguese neonates. Pharm. World Sci. 29(3): 104-108.

Sardão VA, Oliveira PJ, Holy J, Oliveira CR, Wallace KB. (2007) Vital imaging of H9c2 myoblasts exposed to tert-butylhydroperoxide--characterization of morphological features of cell death. BMC Cell Biol. Mar 16;8:11.

Silva BA, Oliveira PJ, Dias AC, Malva JO.(2007) Mitochondria as Targets for Neuronal Protection Against Excitotoxicity: A Role for Phenolic Compounds? Cur. Nerv. Syst. Agents Med. Chem. 7 (3): 205-222.