Biotecnologia e Saúde

Alves S, Nascimento-Ferreira I, Auregan G, Hassig R, Dufour N, Brouillet E, Pedroso de Lima MC, Hantraye P, Déglon N*, Pereira de Almeida* L. (2008) Allele-specific RNA silencing of mutant ataxin-3 mediates neuroprotection in a rat model of Machado-Joseph disease. *Equal Contribution. PLoS ONE Oct 8;3(10):e3341.

Alves S, Régulier E, Nascimento-Ferreira I, Hassig R, Dufour N, Koeppen A, Carvalho AL, Simões S, Pedroso de Lima MC, Brouillet E, Colomer Gould V, Déglon N, Pereira de Almeida L (2008) Striatal and nigral pathology in a lentiviral rat model of Machado-Joseph disease. Hum. Mol. Genet. 17: 2071-2083.

Camacho R, Alves A, Silva CG and Brito RMM (2008) On Mining Protein Unfoling Simulation Data with Inductive Logic Programming. Proceedings of the 2nd International Workshop on Practical Applications of Computational Biology and Bioinformatics (IWPACBB 2008). Advances in Soft Computing 49, 175-179. (ISBN 978-3-540-85860-7)

Cardoso ALC, Simões S, Almeida LP, Plesnila N, Lima MCP, Wagner E and Culmsee C (2008) Tf-lipoplexes for neuronal siRNA delivery in vitro and in vivo: A promising system to mediate gene silencing in the CNS. J. Control. Release 132, 113–123.

Monteiro CJP, Pereira MM, Pinto SMA, Simões AVC, Sá GFF, Arnaut LG, Formosinho SJ, Simões S and Wyatt MF (2008) Synthesis of amphiphilic sulfonamide halogenated porphyrins: MALDI-TOFMS characterization and evaluation of 1-octanol/water partition coefficients. Tetrahedron 64(22), 5132-5138.

Fernandes E, Jorge AM, Silva CG, and Brito RMM (2008). A Knowledge Discovery Method for the Characterization of Protein Unfolding Processes. Proceedings of the 2nd International Workshop on Practical Applications of Computational Biology and Bioinformatics (IWPACBB 2008). Advances in Soft Computing 49, 180-188. (ISBN 978-3-540-85860-7)

Faneca H, Faustino A and Lima MCP (2008) Synergistic antitumoral effect of non-viral HSV-Tk/GCV gene therapy and vinblastine in mammary adenocarcinoma cells. J. Control. Release 126, 175-184.

Ferreira L*, Karp JM, Nobre L, Langer R* (2008) New opportunities: The use of nanotechnologies to manipulate and track stem cells. Cell Stem Cell 3, 136-146. *Corresponding authors.

Ferreira L, Squier T, Park H, Choe H, Kohane DS, Langer R (2008) Human embryoid bodies containing nano- and micro-particulate delivery vehicles. Advanced Materials 20, 2285-2291.

Fuller J, Zugates G, Ferreira L, Ow H, Nguyen N, Wiesner U, Langer R (2008) Intracellular delivery of core-shell fluorescent silica nanoparticles”. Biomaterials 29, 1526- 1532.

Mahdavi A*, Ferreira L*, Sundback C, Nichol JW, Chan EP, Carter JD,Bettinger C, Patanavanich S, Chignozha L, Ben-Joseph E, Galakatos A, Pryor H, Pomerantseva I, Masiakos P, Faquin W, Zumbuehl A, Hong S, Borenstein J, Vacanti J, Langer R, Karp JM (2008) A biodegradable and biocompatible Gecko-inspired tissue adhesive". Proceedings of the National Academy of Sciences 105(7), 2307-2312. *Authors contributed equally.

Moreira JN, Santos A, Moura V, Lima MCP, Simões S (2008) Non-viral lipid-based nanoparticles towards cancer systemic gene silencing. Journal of Nanoscience and Nanotechnology May; 8:2187–2204.

Nobre RJ, Almeida LP, Martins TC. (2008) Complete genotyping of mucosal human papillomavirus using a restriction fragment length polymorphism analysis and an original typing algorithm. J. Clin Virol. May;42(1):13-21. Epub 2008 Mar 4.

Nunes-Correia I, Rodríguez JM, Eulálio A, Carvalho AL, Citovsky V, Simões S, Faro C, Salas ML, Pedroso de Lima MC. African swine fever virus p10 protein exhibits nuclear import capacity and accumulates in the nucleus during viral infection.Vet Microbiol. 2008 Jul 27;130(1-2):47-59.

Penacho N, Filipe A, Simões S and Lima MCP (2008) Transferrin-associated lipoplexes as gene delivery systems: relevance of mode of preparation and biophysical properties. J. Membrane Biology 221, 141-152.

Pereira CS, da Costa DS, Pereira S, Nogueira Fde M, Albuquerque PM, Teixeira J, Faro C, Pissarra J (2008) Cardosins in postembryonic development of cardoon: towards an elucidation of the biological function of plant aspartic proteinases. Protoplasma 232(3-4):203-13.

Rosa M, Penacho N, Simões S, Lima MCP, Lindman B and Miguel MG (2008) DNA precondensation with an amino acid-based cationic amphiphile. A new approach for liposome-based gene delivery. Molecular Membrane Biology 25, 23-34.

Salvador A (2008) Book review: Uri Alon ‘Introduction to Systems Biology’, Math. Biosci. 215:193-195

Santos A, Ribeiro ABS, Lima MCP, Simões S, Moreira JN (2008) Simultaneous evaluation of viability and Bcl-2 in small cell lung cancer. Cytometry – Part A, September; 73A(12):1165-1172.

Soares MIL, Lopes SMM, Cruz PF, Brito RMM, and Melo TMVDP (2008) Flash vacuum pyrolysis of 2,2-dioxo-1H,3H-pyrrolo[1,2-c]thiazoles and 2-vinyl-1H-pyrroles. Tetrahedron 64, 9745-9753.

Swain M, Ostropytskyy V, Silva CG, Stahl F, Riche O, Brito RMM, and Dubitzky W (2008) Grid Computing Solutions for Distributed Repositories of Protein Folding and Unfolding Simulations. Lecture Notes in Computer Science 5103, 70-79.

Trabulo S, Mano M, Faneca H, Cardoso AL, Duarte S, Henriques A, Paiva A, Gomes P, Simões S and Lima MCP (2008) S413-PV cell penetrating peptide and cationic liposomes act synergistically to mediate intracellular delivery of plasmid DNA. J. Gene Medicine 10, 1210-1222.