Cell and Molecular Toxicology

Abrantes AM, Rio J, Tavares LC, Carvalho RA, Botelho MF. (2010) Magnetic resonance spectroscopy in cancer diagnostics. Oncology Rev., 4(3), 177-184.

Ascensão A, Lumini-Oliveira J, Machado NG, Ferreira R, Gonçalves IO, Moreira, Marques F, Sardão VA, Oliveira PJ, Magalhães J. (2010) Acute Exercise Protects Against Calcium-induced Cardiac Mitochondrial Permeability Transition Pore in Doxorubicin Treated rats. Cli. Sci., 120 (1): 37-49.

Cardoso AMS, Faneca H, Almeida JAS, Pais AACC, Marques EF, Lima MCP, and Jurado AS. (2010). Gemini surfactant dimethylene-1,2bis(tetradecyldimethy ammonium bromide)-based gene vectors: A biophysical approach to transfection efficiency. Biochimica et Biophysica Acta, 1808: 341-351.

Carvalho RA, Sousa RP, Cadete VJ, Lopaschuk GD, Palmeira CM, Bjork JA, Wallace KB. (2010) Metabolic remodeling associated with subchronic doxorubicin cardiomyopathy. Toxicology, 270, 92-98.

Cerqueira DA, Filho GR, Carvalho RA, Valente AM. (2010) Caracterização de acetato de celulose obtido a partir de bagaço de cana-de-açúcar por 1H-RMN. Polimeros: Ciência e Tecnologia, 20, 85-91.

Costa ANT, Moreno V, Urbano AM, Alpoim MC. (2010) Responses of Nontumorigenic Human Bronchial Epithelial Cells to Toxicologically Relevant Hexavalent Chromium Exposures, Mol. Carcinog., 49, 582-591.

Costa IM, Serralheiro AI, Rodrigues M, Alves G, Falcão AC. (2010) Usefulness of factor II and factor X as therapeutic markers in patients under chronic warfarin therapy. Biomed. Pharmacother., 64(2):130-2.

Custódio JB, Gonçalves DI, Moreno AJ, Fernandes E, Carvalho F, Vicente JA, Fernandes MA. (2010) Comparative effects of 3,4 methylenedioxy-methamphetamine (ecstasy) and 4-methylthioamphetamine on rat liver mitochondrial function. Toxicology, 270, 99-105.

Figueiras AR, Sarraguça J, Carvalho RA, Veiga FJ, Canelas A. (2010) The role of L-arginine in inclusion complexes of omqeprazole with cyclodextrins. AAPS PharmSciTech, 11(1), 233-240.

Fonseca AC, Jarmelo S, Carvalho RA, Fausto R, Gil MH, Simões PN. (2010) 1H NMR Spectroscopic and Quantum Chemical Studies on a Poly(Ester Amide) Model Compound: Nα-Benzoyl-LArgininate Ethyl Ester Chloride. Structural Preferences for the Isolated Molecule and in Solution. J. Phys. Chem. B, 114(18), 6156-6164.

Gonçalves MJ, Calado-Santos AC, Coelho P, Costa AN, Rodrigues CF, Santos MS, Guiomar AJ, Alpoim MC, Urbano AM. (2010) Changes in the energy status and glucose uptake rate of PC-12 cells induced by acute subcytotoxic or midly cytotoxic hexavalent chromium insults. The FEBS J., 277, 70.

Hafner AV, Dai J, Gomes AP, Chiao YC, Palmeira CM, Rosenzweig A, Sinclair DA. (2010) Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy. Aging, 2(12):914-23.

Holy J, Kolomitsyna O, Krasutsky D, Oliveira PJ, Perkins E, Krasutsky PA. (2010) Dimethylaminopyridine Derivatives of Lupane Triterpenoids are Potent Disruptors of Mitochondrial Structure and Function, Bioinorg. Med. Chem., 18(16):6080-6088.

Ledo A, Barbosa R, Cadenas E, and Laranjinha J. (2010) Dynamic and interaction profiles of NO and O2 in rat hippocampal slices. Free Radic. Biol. Med., 48, 1044-1050.

Lumini-Oliveira J, Ascensão A, Pereira CV, Magalhães S, Marques F, Oliveira PJ, Magalhães J. (2010) Long-term Streptozotocin-induced Hyperglycaemia Impairs Gastrocnemius Mitochondrial Respiratory Function but Increases Resistance to Permeability Transition Pore Opening. Eur. J. Clin. Invest., 40(4):319-29.

Lumini-Oliveira J, Magalhães J, Pereira CV, Oliveira PJ, Ascensão A. (2010) Effect of Moderate Endurance Training Against Reverts in Vitro Heart Mitochondrial Dysfunction and Permeability Transition in Long-term Severe Hyperglycemia. Mitochondrion, 11 (1): 54-63.

Machado M, Dinis AM, Salgueiro L, Cavaleiro C, Custódio JB, Sousa MC. (2010) Anti-Giardia activity of phenolic-rich essential oils: effects of Thymbra capitata, Origanum virens, Thymus zygis subsp. sylvestris and Lippia graveolens on trophozoites growth, viability, adherence and ultrastructure. Parasitol. Res., 106, 1205-1215.

Machado NG, Baldeiras I, Oliveira PJ. (2010) Sub-chronic Administration of Doxorubicin to Wistar Rats Results in Oxidative Stress and Unaltered Apoptotic Signaling in the Lung. Chem-Biol. Interac., 188: 478-486.

Maia J, Carvalho RA, Coelho JFJ, Simões PN, Gil MH. (2010) Insight on the periodate oxidation of dextran and its structural vicissitudes. Polymer, 52, 258-265.

Rocha BS, Gago B, Barbosa RM, and Laranjinha J. (2010) Diffusion of nitric oxide through the gastric wall upon reduction of nitrite by red wine: physiological impact. Nitric Oxide, 22, 235-241.

Roleira F, Siquet C, Orrù E, Garrido EM, Garrido J, Milhazes N, Podda G, Paiva-Martins F, Reis S, Carvalho RA, Tavares da Silva E, Borges F. (2010) New Lipophilic Phenolic Antioxidants: Correlation between Antioxidant Profile, Partition Coefficients, and Redox Properties. Bioorganic & Medicinal Chemistry, 18, 5816-5825.

Roleira FMF, Tavares da Silva EJ, Carvalho RA, Marques MPM. (2010) Lithocholic acid derivative as a model for artificial receptors: a raman study. Lett Drug Design & Discovery, 7(8), 610-617.

Sampaio A, Mendes L, Gonçalves AC, Abrantes M, Sarmento AB, Botelho F, Oliveira P, Carvalho R, Urbano A, Alpoim MC. (2010) Malignant transformation of human bronchial epithelial cells (BEAS-2B) by Cr(VI) is associated with altered mitochondria and bioenergetic phenotype. FEBS J., 277, 224.

Santiago AR, Garrido MJ, Cristóvão AJ, Duarte JMN, Carvalho RA, Ambrósio AF. (2010) Evaluation of the impact of diabetes on retinal metabolites by NMR spectroscopy. Current Eye Research, 35, 992-1001.

Santos RC, Salvador JAR, Marin S, Cascante M, Moreira JN, Dinis TCP. (2010) Synthesis and structure-activity relationship study of novel cytotoxic carbamate and N-acylheterocyclic bearing derivatives of betulin and betulinic acid. Bioorganic & Medicinal Chemistry, 18, 4385-4396.

Silva JP, Sardao VA, Coutinho OP, Oliveira PJ. (2010) Nitrogen Compounds Prevent H9c2 Myoblast Oxidative Stress-induced Mitochondrial Dysfunction and Cell death. Cardiovasc. Toxicol., 10(1):51-65.

Simões AM, Duarte FV, Teodoro JS, Rolo AP, Palmeira CM. (2010) Exposure to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin and tetraethyl lead affects lung mitochondria bioenergetics. Toxicol. Mech. Methods, 20(1):1-6.

Soares AF, Carvalho RA, Veiga FJ, Jones JG. (2010) Effects of galactose on direct and indirect pathway estimates of hepatic glycogen synthesis. Metabolic Engineering, 12, 552-560.

Varela AT, Simões AM, Teodoro JS, Duarte FV, Gomes AP, Palmeira CM, Rolo AP. (2010) Indirubin-3´-oxime prevents hepatic I/R damage by inhibiting GSK-3beta and mitochondrial permeability transition. Mitochondrion, 10(5): 456-463.

Woitiski CB, Neufeld RJ, Veiga F, Carvalho RA, Figueiredo IV. (2010) In vivo evaluation of the therapeutic interest of polymeric nanoparticles for oral insulin delivery. Eur. J. Pharm. Sci., 41, 556-563.

Financiado por Fundos FEDER através do Programa Operacional Factores de Competitividade – COMPETE 2020 e por Fundos Nacionais através da FCT – Fundação para a Ciência e a Tecnologia no âmbito do projecto Estratégico com referência atribuida pelo COMPETE: POCI-01-0145-FEDER-007440

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