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| Vectors and Gene Therapy |
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| PhD position: MicroRNA-based strategies to treat Machado-Joseph disease |
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A position is opened for a highly motivated graduate (Ph.D.) student to study microRNA-based strategies to modify or block the pathogenesis of the polyglutamine disorder, Machado-Joseph disease /spinocerebellar ataxia type 3. Our group employs a multidisciplinary approach using viral vectors and other gene therapy tools to produce and study cell and rodent models of disease, allied to in vivo and in vitro biochemical, immunohistochemical, behavioural and imaging methods to explore this subject.
The project is part of an EU-funded Graduate Students Training Network of Excellence where collaboration with leading laboratories in Europe is an integral part of the training program. See http://treatpolyq.eu/concept.html
Applicants should preferably have an MSc or equivalent degree. A background in molecular biology and neuroscience methodologies will be of great advantage. Demonstrated proficiency in written/spoken English is mandatory. The Marie Curie ITN regulations require that the candidate has not lived in Portugal for longer than 12 months in the past three years and has less than 4 years postgraduate working experience.
Please send application (a letter of interest describing briefly your career, CV, list of publications, and two letters of reference) to Luis Pereira de Almeida (via e-mail) at the care of Silvia Sousa (silvia@cnc.uc.pt).
Prof. Luis Pereira de Almeida, PhD
Center for Neuroscience and Cell Biology and Faculty of Pharmacy
University of Coimbra
Largo Marquês de Pombal
3004-517 Coimbra
Portugal
Tel: +351 96 633 74 82
Luis Pereira de Almeida: luispa@cnc.uc.pt
Silvia Sousa (contract & grants officer): silvia@cnc.uc.pt
URL: http://www.cnbc.pt/research/areaB41_4.asp?lg=2
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