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| Amílcar C. Falcão |
| Group Leader |
Full Professor
Faculty of Pharmacy
University of Coimbra |
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+351 239 855090 |
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+351 239 855099 |
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| Objectivo |
| A Farmacometria é a ciência que se dedica ao desenvolvimento e aplicação de modelos farmacoestatísticos direccionados para a caracterização, compreensão e predição do comportamento cinético e dinâmico dos fármacos, biomarcadores e outros descritores clínicos (ver esquema). Na realidade, a Farmacometria permite uma correcta interpretação e descrição da farmacologia na sua vertente quantitativa. |
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| Constituição do grupo |
| Gilberto Alves |
| Ph.D. Student |
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| António Sales Mano |
| Ph.D. Student |
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| Bruno Lopes |
| Ph.D. Student |
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| Ana Fortuna |
| Ph.D. Student |
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| Publicações |
Simultaneous and enantioselective liquid chromatographic determination of eslicarbazepine acetate, S-licarbazepine, R-licarbazepine and oxcarbazepine in mouse tissue samples using ultraviolet detection. Analytica Chimica Acta. 2007 (In Press)
Enantioselective HPLC-UV method for eslicarbazepine acetate (BIA 2-093) and its metabolites determination in human plasma. Biomedical Chromatography. 2007 (In Press)
Performance of gentamicin population kinetic parameters in Portuguese neonates. Pharmacy World & Science. 2007 (In Press)
Cyclodextrin multicomponent complexation and controlled release delivery strategies to optimise the oral bioavailability of vinpocetine. Journal of Pharmaceutical Science. 2007 (In Press)
Effects of nebicapone on levodopa pharmacokinetics, COMT activity and motor fluctuations in Parkinson’s disease. Clinical Neuropharmacology. 2007 (In Press)
Effect of gender on the pharmacokinetics of eslicarbazepine acetate (BIA 2-093), a new voltage-gated sodium channel blocker. Biopharmaceutics & Drug Disposition. 2007, 28: 249-256
Vancomycin kinetic profile in very low birth weight newborns. European Journal of Hospital Pharmacy. 2006, 12(2): 29-31.
The potential for CA-125 increase rate to predict ovarian cancer relapse. European Journal of Hospital Pharmacy. 2006, 12(3): 60-62.
Lamotrigine pharmacokinetic evaluation in Portuguese epileptic patients submitted to VEEG monitoring. European Journal of Clinical Pharmacology. 2006, 62: 737-742.
CA-125 AUC robustness as a predictor for a complete response to primary chemotherapy in ovarian cancer: a multivariant analysis using ANN. Recent Advances & Research Updates. 2006, 7(2): 143-148.
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| Currículo |
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Academic Degrees:
1989 - Pharm. D. (University of Coimbra)
1995 - Ph.D. (University of Coimbra)
2001 - Aggregation in Pharmacy (University of Coimbra) |
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Awards:
1989 – Portuguese Pharmaceutical Society Award
1991 – Portuguese Pharmacists College Award
1997 – Portuguese Pediatrics Society Award
2001 – Portuguese League Against Epilepsy Award
2002 – Portuguese League Against Epilepsy Award
2006 - Eminent Scientist of the Year 2006 - Europe (Clinical Pharmacology); award conferred by the International Research Promotion Council (IRPC). |
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| Links |
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| http://www.ff.uc.pt |
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