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| Margarida Carneiro |
| Group Leader |
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Ph. |
+351 239 104424 |
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Mailing address:
Immunology Group
Center for Neurosciences and Cell Biology
University of Coimbra
Largo Marquês de Pombal
3004-158 Coimbra
Visitors address:
Immunology Group
Center for Neurosciences and Cell Biology
3rd Floor, Campus 1
Faculty of Medicine, University of Coimbra
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| Collaborations |
José António Pereira da Silva, Department of Rheumatology, Hospitais da Universidade de Coimbra
João Eurico da Fonseca, Instituto de Medicina Molecular, University of Lisbon
Rikard Holmdahl, Medical Inflammation Research Group, Karolinska Institute, Sweden
Richard Siegel, National Institute of Arthritis and Musculoskeletal Diseases, NIH, Bethesda (MD), USA
Rachel Ettinger, MedImmune, Gaithersburgh (MD), USA
Riitta Lahesmaa, Turku Centre for Biotechnology, University of Turku, Finland
Ruth Fritsch, Department of Rheumatology, University of Utrecht, Netherlands
Karl Skriner, Department of Rheumatology, Charité-Berlin, Germany
Mohammed Daha, Departament of Nephrology, University of Leiden, Netherlans
Grupo Português de Immunodeficiências Primárias
Stephen Kilfeather, Aeirtec Ltd, New Castle, UK
Shahira Elshafeey, Department of Pathology, University of Fayoum, Egypt
Isabel Santana, Neurology Department, Hospitais da Universidade de Coimbra
Cristina Januário, Neurology Department, Hospitais da Universidade de Coimbra
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| Funding Sources |
| European Union- FP7-PEOPLE-ERG-2008-LIF239422 |
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| Selected Publications |
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Raposo BR, Rodrigues-Santos P, Carvalheiro H, Agua-Doce AM, Carvalho L, Pereira da Silva JA, Graça L, Souto-Carneiro MM. Monoclonal anti-CD8 therapy induces disease amelioration in the K/BxN mouse model of spontaneous chronic polyarthritis. Arthritis Rheum. 2010 Oct;62(10):2953-62.
Souto-Carneiro MM, Mahadevan V, Takada K, Fritsch R, Nanki T, Brown M, Fleisher TA, Wilson M, Goldbach-Mansky R, Lipsky PE. (2009). Alterations in peripheral blood memory B cells in patients with active rheumatoid arthritis are dependent on the action of TNF. Arth Res Ther. 11(3):R84. This paper is tagged by BioMed Central as Highly Accessed.
Souto-Carneiro MM, Fritsch R, Sepulveda N, Lagareiro MJ, Morgado N, Longo NS, Lipsky PE. (2008). The NF-κB canonical pathway is involved in the control of the exonucleolytic processing of coding-ends during V(D)J recombination. J Immunol 180(2):1040-9.
Bleesing JJ, Souto-Carneiro MM, Savage WJ, Brown MR, Novicio C, Yavuz S, Brenner S, Siegel RM, Horwitz ME, Lipsky PE, Malech HL, Fleisher TA. (2006) Patients with chronic granulomatous disease have a reduced peripheral blood memory B-cell compartment. J Immunol 176 (11): 7096-103.
Souto-Carneiro MM, Sims GP, Girschik H, Lee J, Lipsky PE. (2005). Developmental changes in the human heavy chain CDR3. J Immunol 175(11):7425-36.
Souto-Carneiro MM, Longo N, Russ D, Sun HW, Lipsky PE. (2004). Characterisation of the Human Immunoglobulin Heavy Chain Antigen Binding Complementary Determining Region 3 using a Newly-Developed Software Algorithm, JOINSOLVER. J Immunol 172(11): 6790-802.
Souto-Carneiro MM, Burkhardt H, Muller EC, Hermann R, Otto A, Kraetsch HG, Sack U, Konig A, Heinegard D, Muller-Hermelink HK, Krenn V (2001). Human monoclonal rheumatoid synovial B lymphocyte hybridoma with a new disease-related specificity for cartilage oligomeric matrix protein. J Immunol 166(6): 4202-8.
7. Souto-Carneiro MM, Krenn V, Hermann R, Konig A, Muller-Hermelink HK (2000). IgVH Genes from different anatomical regions -with different histopathological patterns- of a rheumatoid arthritis patient suggest cyclic re-entry of mature synovial B-cells in the hypermutation process. Arthritis Research 2 (4): 303-314. |
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| Short Curriculum Vitae |
1997- Diploma in Biochemistry, Faculty of Sciences, University of Lisbon
2000- PhD Degree in Immunology, Faculty of Biology, University of Würzburg, Germany
1996-1997- Graduation Student, Institute for Experimental Immunology, University of Marburg, Germany
1997-2000- PhD Student/Scientific Assistant, Institute for Pathology, University of Würzburg, Germany
2001-2004- Post-doctoral fellow, National Institute of Arthritis and Musculoskeletal Diseases (NIAMS), NIH, Bethesda (MD), USA
2006-2008- Marie Curie Fellow/ Junior Investigator, Instituto Gulbenkian de Ciência, Oeiras, Portugal
2008-2009- Invited Researcher, Instituto de Medicina Molecular, University of Lisbon, Portugal
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| Awards |
2005- Young Investigator Award from the European League Against Rheumatism (EULAR)
2001- Scientific Presentation Excellence Award, NIAMS
1999- 2nd Poster Prize, German Society for Pathology
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