Biotechnology is an enabling technology with the potential to develop new products and services with impact across different economic sectors.

CNC has established three main scientific areas as the focus of the Biotechnology domain research activity: Stem cells and tissue engineering, Molecular and microbial biotechnology, and Computational Biology

The main goals are:

  • To develop platforms for drug-screening and toxicology assessment;
  • To modulate the activity/differentiation of endo- and exogenous stem cells by biomaterials;
  • To study microbial diversity, ecology and biotechnology of microorganisms living at very high temperature, high salinity and extreme resistant to radiation/desiccation;
  • To discover new compatible solutes (osmolytes) that protect extremophiles from stress conditions, and to elucidate their biosynthetic pathways;
  • To analyze how biologically widespread sub-networks (circuits) perform according to various engineering-inspired criteria as compared to less widespread alternatives, and to understand what makes those designs preferable to other alternatives and abstract the general principles involved.
Research labs    
Lino Ferreira   Biomaterials and Stem Cell-Based Therapeutics
Carlos Filipe Pereira   Cell reprogramming and developmental hematopoiesis
Mário Grãos   Cellular Mechanobiology
Armindo Salvador   Computational & Systems Biology
Irina S. Moreira   Data Driven Molecular Design
Miguel Mano   Functional Genomics and RNA-Based Therapeutics
Isaura Simões   Microbial and Molecular Biotechnology
Milton S. Costa   Microbiology of Extreme Environments
Alexandra Teresa Pires Carvalho   Rational protein engineering
Ana Eulálio   RNA & Infection
Ricardo Neves   Stem cell metabolism
Hugo Fernandes   Stem cells and drug screening
Ricardo S. Vieira-Pires   Structural Biotechnology
Financiado por Fundos FEDER através do Programa Operacional Factores de Competitividade – COMPETE 2020 e por Fundos Nacionais através da FCT – Fundação para a Ciência e a Tecnologia no âmbito do projecto Estratégico com referência atribuida pelo COMPETE: POCI-01-0145-FEDER-007440

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