Selected Publications
Abreu, T. R., Fonseca, N. A., Gonçalves, N., & Moreira, J. N. (2020). Current challenges and emerging opportunities of CAR-T cell therapies. J Control Release, 319, 246–261. https://doi.org/10.1016/j.jconrel.2019.12.047
Romano, Sofia, Fonseca, N., Simões, S., Gonçalves, J., & Moreira, J. N. (2019). Nucleolin-based targeting strategies for cancer therapy: From targeted drug delivery to cytotoxic ligands. Drug Discovery Today, 24(10), 1985–2001. https://doi.org/10.1016/j.drudis.2019.06.018
Romano, S., Moura, V., Simoes, S., Moreira, J. N.*, & Goncalves, J.* (2018). Anticancer activity and antibody-dependent cell-mediated cytotoxicity of novel anti-nucleolin antibodies. Sci Rep, 8(1), 7450. https://doi.org/10.1038/s41598-018-25816-8. *Corresponding authors.
Gregorio, A. C., Fonseca, N. A., Moura, V., Lacerda, M., Figueiredo, P., Simoes, S., Dias, S., & Moreira, J. N. (2016). Inoculated Cell Density as a Determinant Factor of the Growth Dynamics and Metastatic Efficiency of a Breast Cancer Murine Model. PLoS One, 11(11), e0165817. https://doi.org/10.1371/journal.pone.0165817
Fonseca, N. A., Rodrigues, A. S., Rodrigues-Santos, P., Alves, V., Gregorio, A. C., Valerio-Fernandes, A., Gomes-da-Silva, L. C., Rosa, M. S., Moura, V., Ramalho-Santos, J., Simoes, S., & Moreira, J. N. (2015). Nucleolin overexpression in breast cancer cell sub-populations with different stem-like phenotype enables targeted intracellular delivery of synergistic drug combination. Biomaterials, 69, 76–88. https://doi.org/10.1016/j.biomaterials.2015.08.007
Fonseca, N. A., Gomes-da-Silva, L. C., Moura, V., Simoes, S., & Moreira, J. N. (2014). Simultaneous active intracellular delivery of doxorubicin and C6-ceramide shifts the additive/antagonistic drug interaction of non-encapsulated combination. J Control Release, 196, 122–131. https://doi.org/10.1016/j.jconrel.2014.09.024
Fonseca, N. A., Gregorio, A. C., Valerio-Fernandes, A., Simoes, S., & Moreira, J. N. (2014). Bridging cancer biology and the patients’ needs with nanotechnology-based approaches. Cancer Treat Rev, 40(5), 626–635. https://doi.org/10.1016/j.ctrv.2014.02.002
Gomes-da-Silva, L. C., Fernandez, Y., Abasolo, I., Schwartz, S., Jr., Ramalho, J. S., Pedroso de Lima, M. C., Simoes, S., & Moreira, J. N. (2013). Efficient intracellular delivery of siRNA with a safe multitargeted lipid-based nanoplatform. Nanomedicine (Lond), 8(9), 1397–1413. https://doi.org/10.2217/nnm.12.174
Gomes-da-Silva, L. C., Fonseca, N. A., Moura, V., Pedroso de Lima, M. C., Simões, S., & Moreira, J. N. (2012). Lipid-based nanoparticles for siRNA delivery in cancer therapy: Paradigms and challenges. Acc. Chem. Res., 45(7), 1163–1171. https://doi.org/10.1021/ar300048p
Moura, V., Lacerda, M., Figueiredo, P., Corvo, M. L., Cruz, M. E., Soares, R., de Lima, M. C., Simões, S., & Moreira, J. N. (2012). Targeted and intracellular triggered delivery of therapeutics to cancer cells and the tumor microenvironment: Impact on the treatment of breast cancer. Breast Cancer Res. Treat., 133(1), 61–73. https://doi.org/10.1007/s10549-011-1688-7
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