AREA A: NEUROSCIENCE AND DISEASE
Coordinator - Catarina Oliveira
Research in Neuroscience and Disease focuses not only on the understanding of normal brain function but also on the causes leading to the failure of function occurring in age-related and neurodegenerative diseases, such as Alzheimer’s, Parkinson’s, Huntington’s, Epilepsy and Retinal dysfunction.

The major questions that confront the groups integrated in this area are the molecular mechanisms of cellular and synaptic plasticity, leading to a better understanding of the mechanisms of neurodegeneration and to a greater insight into the mechanisms of neuroprotection, which promise to shed light on the therapeutical strategies in a wide range of neurodegenerative disorders, and open new strategies for brain repair through the manipulation of neurogenesis. The contribution of mitochondria impairment and energy failure to neuronal cell death is also a major interest of research.
Groups
Mitochondrial Dysfunction and Signaling in Neurodegeneration
A. Cristina Rego
Glutamatergic Synapses
Ana Luísa Carvalho
Molecular Mechanisms of Disease
Cláudia M. Fragão Pereira
Neuromodulation
Rodrigo A. Cunha
Neuronal Cell Death and Neuroprotection
Carlos B. Duarte
Neuroprotection and Neurogenesis in Brain Repair
João Malva
Neuroendocrinology and Neurogenesis Group
Cláudia Cavadas
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